Mostrando 61 - 80 Resultados de 84 Para Buscar '"VH1"', tiempo de consulta: 0.12s Limitar resultados
  1. 61
    “…The mean decrease in postoperative hemoglobin level was minimum in single-port LAVH (1.8 g/dL) and VH (1.8 g/dL). Conversion to open surgery or multi-port surgery occurred in five cases (0.6%). …”
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    Clinical outcomes of hysterectomy for benign diseases in the female genital tract: 6 years’ experience in a single institute
  2. 62
    por Hyneman, Rachel Jordan
    Publicado 2020
    “…The observed signal strength of the $ggF$ production mode was found to be $\mu_{ggF} = 0.97^{+0.17}_{-0.15} $, that of the $VBF$ production mode $\mu_{VBF} = 1.4^{+0.44}_{-0.37}$, and that of the combined $VH$ processes ($W^{\pm}H$, $q\overline{q}ZH$, and $ggZH$) is measured to be $\mu_{VH} = 1.09^{+0.61}_{-0.55}$. These results are all consistent with the Standard Model predictions, and so no direct evidence of new physics is observed.…”
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    Measuring Higgs Boson Couplings, including to the Top Quark, in the Diphoton Decay Channel with Run 2 Data Collected by the ATLAS Detector
  3. 63
    Publicado 1993
    “…In contrast to the WA mRFs H chains in which VH1 genes are used, the 35G6 IgM expresses a VH3 gene. …”
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    Human rheumatoid factor cross-idiotypes. IV. Studies on WA XId-positive IgM without rheumatoid factor activity provide evidence that the WA XId is not unique to rheumatoid factors and is distinct from the 17.109 and G6 XIds
  4. 64
    “…The phage display analysis technique confirmed the intestinal production of the anti-TG2 antibodies; however, whereas the serum-positive type 1 diabetic patients showed a preferential use of the VH5 antibody gene family, in the serum-negative patients the anti-TG2 antibodies belonged to the VH1 and VH3 families, with a preferential use of the latter. …”
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    Majority of Children With Type 1 Diabetes Produce and Deposit Anti-Tissue Transglutaminase Antibodies in the Small Intestine
  5. 65
    “…VH3-23) with no or isolated good-prognosis cytogenetic alterations, a second group which mainly consisted of clinical MBL(hi) and advanced stage CLL with a skewed but different CLL-associated IGHV gene repertoire (e.g. VH1-69), frequently associated with complex karyotypes and poor-prognosis cytogenetic alterations, and a third group of clones with intermediate features, with prevalence of mutated IGHV genes, and higher numbers of del(13q)(+) clonal B-cells. …”
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    Combined Patterns of IGHV Repertoire and Cytogenetic/Molecular Alterations in Monoclonal B Lymphocytosis versus Chronic Lymphocytic Leukemia
  6. 66
    “…RESULTS: Using the analysis of microarray data available for grapevine, six possible reference genes were selected for RT-qPCR validation: PADCP, ubiq, TIF, TIF-GTP, VH1-IK, aladin-related. Two additional genes that are commonly used as reference genes were included: act and L2. …”
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    Microarray-based uncovering reference genes for quantitative real time PCR in grapevine under abiotic stress
  7. 67
    “…Interestingly, the BCR repertoire of these cells was altered in RA, demonstrating decreased diversity with preferential usage alteration from VH3-23D to VH1-8. Single cell sequencing further revealed the proinflammatory biased features of these cells in RA. …”
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    Impaired CD27(+)IgD(+) B Cells With Altered Gene Signature in Rheumatoid Arthritis
  8. 68
    “…We found multiple differences between the productive repertoires of HIVD and HD subjects, including biased usages of VH3-49, VH1-2, VH3-33, VH3-74, and VH5-51 in VH and D1-7, D1-14, D1-20, and D5-5/18 in D segments in the HIVD group, as well as shorter and preferential glycine usages in CDRH3 regions. …”
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    Characteristics of Plasmablast Repertoire in Chronically HIV-Infected Individuals for Immunoglobulin H and L Chain Profiled by Single-Cell Analysis
  9. 69
    “…This study describes the use of formalin-killed Vibrio harveyi (FKVh) strain Vh1 as a vaccine candidate to stimulate innate and adaptive immunities against vibriosis in a marine red hybrid tilapia model. …”
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    Efficacy of Whole Cell Inactivated Vibrio harveyi Vaccine against Vibriosis in a Marine Red Hybrid Tilapia (Oreochromis niloticus × O. mossambicus) Model
  10. 70
    “…In contrast, after vaccination, the proportion of IgD/M BCRs increase, SHM is unchanged, and expansion of IgG clones is prominent. VH1-24, which targets the N-terminal domain (NTD) and contributes to neutralization, is expanded post infection except in the most severe disease. …”
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    B cell receptor repertoire kinetics after SARS-CoV-2 infection and vaccination
  11. 71
    “…BACKGROUND: The 21-kDa Vaccinia virus VH1-related (VHR) dual-specific protein phosphatase (encoded by the DUSP3 gene) plays a critical role in cell cycle progression and is itself regulated during the cell cycle. …”
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    Cervix carcinoma is associated with an up-regulation and nuclear localization of the dual-specificity protein phosphatase VHR
  12. 72
    “…BACKGROUND: VHZ is a VH1-like (member Z) dual specific protein phosphatase encoded by DUSP23 gene. …”
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    VHZ is a novel centrosomal phosphatase associated with cell growth and human primary cancers
  13. 73
    “…The CD4 binding site (CD4bs) of the HIV-1 envelope glycoprotein is susceptible to multiple lineages of broadly neutralizing antibodies (bnAbs) that are attractive to elicit with vaccines. The CH235 lineage (VH1-46) of CD4bs bnAbs is particularly attractive because the most mature members neutralize 90% of circulating strains, do not possess long HCDR3 regions, and do not contain insertions and deletions that may be difficult to induce. …”
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    Neutralization-guided design of HIV-1 envelope trimers with high affinity for the unmutated common ancestor of CH235 lineage CD4bs broadly neutralizing antibodies
  14. 74
    “…Although the VH3 framework (FWR) is commonly used in CDR grafting, we found the VH1 framework (FWR) to be a possible alternative when grafting IgA1 and 2 owing to its stronger binding to antigen Her2 and weaker interactions to superantigen Protein L and A. …”
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    Variable-heavy (VH) families influencing IgA1&2 engagement to the antigen, FcαRI and superantigen proteins G, A, and L
  15. 75
    “…TXG-0078 achieves its exceptional binding breadth while utilizing the same VH1–24 variable gene signature and heavy chain-dominant binding pattern seen in other NTD supersite-specific neutralizing Abs with much narrower specificity. …”
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    Deep repertoire mining uncovers ultra-broad coronavirus neutralizing antibodies targeting multiple spike epitopes
  16. 76
    Publicado 1994
    “…Five VH genes in three VH families were used by these antibodies (Ab), including VH1 (dp21/1-4b and dp10 [51p1]/hv1051), VH3 (dp38/3-15 and dp77/13-21), and VH4 (dp70/4-4b). …”
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    Human rheumatoid factors with restrictive specificity for rabbit immunoglobulin G: auto- and multi-reactivity, diverse VH gene segment usage and preferential usage of V lambda IIIb
  17. 77
    “…Study 1 evaluated the prophylactic and therapeutic efficacy of TMC353121 at a target plasma level of 50 ng/mL (n=15; Group 1: prophylactic arm [Px50], 0.033 mg/mL TMC353121, flow rate 2.5 mL/kg/h from 24 hours pre-infection to 10 days; Group 2: therapeutic arm [Tx50], 0.033mg/mL TMC353121 from 24 hours postinfection to 8 days; Group 3: control [Vh1] vehicle, 24 hours post-infection to 8 days). …”
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    Antiviral Activity of TMC353121, a Respiratory Syncytial Virus (RSV) Fusion Inhibitor, in a Non-Human Primate Model
  18. 78
    “…However, the memory B cells that developed in antibody recipients differed from controls in that they were not enriched in VH3–53, VH1–46 and VH3–66 genes and predominantly expressed low-affinity IgM antibodies that carried small numbers of somatic mutations. …”
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    Antibody feedback regulation of memory B cell development in SARS-CoV-2 mRNA vaccination
  19. 79
    por Chang, Arthur, Hicar, Mark D
    Publicado 2023
    “…Within HIV infected persons the two most shared clones both used VH1-18, JH4, had CDRaa 8, and were immature IGM/D. …”
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    257. Shared antibody sequences reveal novel public clonotypes of antibodies within and between HIV infected and healthy individuals
  20. 80
    “…When the variable chain (predicted to be VH1-02 derived) was mutated to germline (termed C group 76 ancestor, or 76Canc), surprisingly this Ab still exhibited significant ADCC activity. …”
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    274. Potential HIV vaccine gp41 epitope targeting antibodies identify peptides with similarity to proposed Kawasaki disease related peptide, suggesting non-specific mimotope targeting of acidic amino acid enriched regions
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