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201por Palomba, Stefano, Daolio, Jessica, Romeo, Sara, Battaglia, Francesco Antonino, Marci, Roberto, La Sala, Giovanni Battista“…Current review highlights a close relationship in women between stress, QoL and reproductive function, that this association is more likely reported in infertile rather than fertile women, and that a vicious circle makes them to have supported each other. …”
Publicado 2018
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202por Lewandowicz, Andrzej, Skowronek, Paweł, Maksymiuk-Kłos, Agnieszka, Piątkiewicz, Paweł“…The association of diabetes with Geriatric Giants reveals as a vicious circle with the background of neurovascular complications. …”
Publicado 2018
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203“…Especially, boys with autism reported more anger after being bullied, suggesting a tenacious vicious circle: these youngsters are likely to be angered when being bullied, which, in turn, makes them a target for bullies. …”
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204por De Nola, Rosalba, Menga, Alessio, Castegna, Alessandra, Loizzi, Vera, Ranieri, Girolamo, Cicinelli, Ettore, Cormio, Gennaro“…Their milieu acquires specific properties thanks to intense crosstalk between stromal and cancer cells, leading to a vicious circle. Fibroblasts, pericytes, lymphocytes and tumor associated-macrophages orchestrate most of the biological pathways. …”
Publicado 2019
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205por VOET, NICOLINE B.M.“…Many NMD patients are captured in a vicious circle of physical inactivity, and it is important to let patients adhere to an active lifestyle, in order to prevent further chronic cardiovascular and muscle deconditioning and increased cardiovascular health risks. …”
Publicado 2019
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206por Liu, Ruiyuan, Yang, Jun, Liu, Linying, Lu, Zhiguo, Shi, Zhuyan, Ji, Weihong, Shen, Jie, Zhang, Xin“…Alzheimer's disease (AD) is a devastating neurodegenerative disorder characterized by progressive cognitive and memory loss. The vicious circle between dysfunctional microglia and amyloid‐β (Aβ) is a crucial pathological event and accelerates the progression of AD. …”
Publicado 2019
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207“…In AD, oxidative stress, neuroinflammation and glutamatergic pathway operate in a vicious circle driven by the dysregulation of the WNT/β-catenin pathway. …”
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208“…In recent years, several new pharmaceuticals targeting bone metabolism such as denosumab or androgen pathway targeting drugs (abiraterone acetate and enzalutamide) have been approved for the treatment of progressive disease aiming to interrupt the vicious circle of bone metastasis and aberrant bone resorption. …”
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209“…These changes would impose initiation of a vicious circle further increasing the frequency of vascular events and hemorrhages within remaining islets until the patient eventually loses all beta-cells and becomes c-peptide negative.…”
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210por Periman, Laura M., Perez, Victor L., Saban, Daniel R., Lin, Meng C., Neri, Piergiorgio“…Several therapeutics are available to break the vicious circle of DED and prevent chronic disease and progression, including immunosuppressive agents (steroids) and immunomodulators (cyclosporine and lifitegrast). …”
Publicado 2020
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211por Pugnaloni, Sofia, Alia, Sonila, Mancini, Margherita, Santoro, Vito, Di Paolo, Alice, Rabini, Rosa Anna, Fiorini, Rosamaria, Sabbatinelli, Jacopo, Fabri, Mara, Mazzanti, Laura, Vignini, Arianna“…In conclusion, it can be hypothesized that a general alteration of taste function can lead patients with type 2 diabetes to search for foods richer in sugars, as in a vicious circle, thus decreasing the likelihood of remission of diabetes mellitus.…”
Publicado 2020
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212“…Since neuroinflammation can be induced or worsened by the virus infection itself, as well as by stressful conditions like those linked to the recent pandemic, the role of neuroinflammatory mechanisms could be central in a vicious circle leading to an increase in the mortality risk in aged COVID-19 patients. …”
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213“…The liver disease is associated with the hyper-IgM immunophenotype and escalating neurodegeneration, creating a vicious circle of immune deficiency, permanent systemic inflammatory response, and organ-specific immunopathology.…”
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214“…In the artwork, imagination, play and fantasy offer creative space to stop the vicious circle of nightmares by changing theme, story line, ending, or any part of the dream into a more positive and acceptable one. …”
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215“…These studies suggest that citrullinated histone H4 could serve as a brake in the pathology of NETs, slowing down the vicious circle between histone H4 and NETs.…”
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216“…Specifically, these treatment trials generally target: (a) the correction of suppressed endocrine axes, notably through a “reactivation” of the pituitary gland's pulsatile secretion of tropic hormones, or (b) the interruption of the “vicious circle” between inflammation, oxidative and nitrosative stress (O&NS), and low thyroid hormone function. …”
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217“…Nevertheless, the inflammatory cascade will be evoked after vast Aβ aggregate binding to pattern recognition receptors on the cell membrane, which then significantly decreases the expression of these receptors and further deteriorate Aβ deposition. This vicious circle will weaken the ability of microglia for Aβ elimination. …”
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218por Genovese, Giovanni, Meduri, Alessandro, Muscatello, Maria Rosaria Anna, Gangemi, Sebastiano, Cedro, Clemente, Bruno, Antonio, Aragona, Pasquale, Pandolfo, Gianluca“…We propose a model of disease where stress exacerbates prior specific traits in a vicious circle where some traits might be involved in disease progression and manifestation. …”
Publicado 2021
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219por Scala, Emanuele, Cacciapuoti, Sara, Garzorz-Stark, Natalie, Megna, Matteo, Marasca, Claudio, Seiringer, Peter, Volz, Thomas, Eyerich, Kilian, Fabbrocini, Gabriella“…The inflammatory vicious circle finally results in pain, purulence, tissue destruction, and scarring. …”
Publicado 2021
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220por Lucchesi, Alessandro, Napolitano, Roberta, Bochicchio, Maria Teresa, Giordano, Giulio, Napolitano, Mariasanta“…The platelet contribution to thrombin generation results in triggering a vicious circle supported by the PARs/TGF-beta axis. PAR antagonists could therefore be a good option for target therapy, both to contain the risk of vascular events and to slow the progression of the disease towards end-stage forms. …”
Publicado 2021
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