-
481por Dillinger, Andrea E., Weber, Gregor R., Mayer, Matthias, Schneider, Magdalena, Göppner, Corinna, Ohlmann, Andreas, Shamonin, Mikhail, Monkman, Gareth J., Fuchshofer, Rudolf“…Such a scenario may finally result in a vicious circle in the pathogenesis of POAG. The transgenic CTGF-overexpressing mouse model might be an optimal model to study the chronic pathological POAG changes in the ONH.…”
Publicado 2022
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
482por Wiesinger, Hans-Peter, Buchecker, Michael, Müller, Erich, Stöggl, Thomas, Birklbauer, Jürgen“…Without targeted balance stimuli, YO likely end in a lifelong vicious circle of mutually dependent poor balance regulation and low physical activity.…”
Publicado 2022
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
483“…Whatever the original trigger of neuroinflammation in PD, what appears quite clear is that the aberrant activation of glial cells and other components of the immune system creates a vicious circle in which neurodegeneration and neuroinflammation nourish each other. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
484por Doganci, Suat, Ince, Mehmet Emin, Demeli, Meric, Ors Yildirim, Nadide, Pehlivanoglu, Bilge, Yildirim, Alperen Kutay, Gianesini, Sergio, Chi, Yung-Wei, Yildirim, Vedat“…Chronic venous disease (CVD) is a proqgressive and underestimated condition related to a vicious circle established by venous reflux and endothelial inflammation, leading to vein dilation and histology distortion, including loss of media tone. …”
Publicado 2023
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
485por El Sayed, Salah Mohamed“…Best anticancer applications based on this hypothesis are: breaking this closed vicious circle using siRNA to target GAPDH and LDH, avoiding strong oxidants (as many cancer chemotherapeutics), and using strong antioxidants for causing antioxidant–oxidant antagonism or antioxidant–lactate antagonism to inhibit the Warburg effect. …”
Publicado 2023
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
486HSV-1 cellular model reveals links between aggresome formation and early step of Alzheimer’s diseasepor Albaret, Marie Alexandra, Textoris, Julien, Dalzon, Bastien, Lambert, Jérémy, Linard, Morgane, Helmer, Catherine, Hacot, Sabine, Ghayad, Sandra E., Ferréol, Martial, Mertani, Hichem C., Diaz, Jean-Jacques“…Therefore, from our study we propose that caspase-dependent production of Aβ42 oligomers together with the abortosis-like event represents a vicious circle in early Alzheimer’s disease stages leading to a chronic amplification of Aβ42 oligomers that contributes to the establishment of degenerative disorder like Alzheimer’s disease in patients infected by HSV-1. …”
Publicado 2023
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
487por Maunder, Robert G., Heeney, Natalie D., Greenberg, Rebecca A., Jeffs, Lianne P., Wiesenfeld, Lesley A., Johnstone, Jennie, Hunter, Jonathan J.“…CONCLUSION: Aspects of burnout that were associated with experiencing greater moral distress occurred both prior to and following moral distress, consistent with the hypotheses that burnout both amplifies moral distress and is increased by moral distress. This potential vicious circle, in addition to an association between moral distress and considering leaving one’s job, suggests that interventions for moral distress may help mitigate a workforce that is both depleted and burdened with burnout.…”
Publicado 2023
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
488por Berge, Rolf K., Ramsvik, Marie S., Bohov, Pavol, Svardal, Asbjørn, Nordrehaug, Jan E., Rostrup, Espen, Bruheim, Inge, Bjørndal, Bodil“…BACKGROUND: Lipid abnormalities, enhanced inflammation and oxidative stress seem to represent a vicious circle in atherogenesis, and therapeutic options directed against these processes seems like a reasonable approach in the management of atherosclerotic disorders. …”
Publicado 2015
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
489por Frazzini, V, Guarnieri, S, Bomba, M, Navarra, R, Morabito, C, Mariggiò, M A, Sensi, S L“…These steps may set a deleterious vicious circle that eventually helps to promote excitotoxic damage found in the AD brain.…”
Publicado 2016
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
490por Dreser, Alice, Vollrath, Jan Tilmann, Sechi, Antonio, Johann, Sonja, Roos, Andreas, Yamoah, Alfred, Katona, Istvan, Bohlega, Saeed, Wiemuth, Dominik, Tian, Yuemin, Schmidt, Axel, Vervoorts, Jörg, Dohmen, Marc, Beyer, Cordian, Anink, Jasper, Aronica, Eleonora, Troost, Dirk, Weis, Joachim, Goswami, Anand“…Taken together, our results support the notion that E102Q-SigR1-mediated ALS pathogenesis comprises a synergistic mechanism of both toxic gain and loss of function involving a vicious circle of altered ER function, impaired protein homeostasis and defective RBPs.…”
Publicado 2017
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
491por Sattler, Cornelia, Schrader, Julian, Flor, Rica Joy, Keo, Makarakpakphea, Chhun, Sokunroth, Choun, Saban, Hadi, Buyung Asmara Ratna, Settele, Josef“…Beneficial arthropods decrease in such environments while pesticide-resistant herbivores can increase, which, in turn, leads to even higher pesticide applications. To break the vicious circle, it is important to implement sustainable farming approaches. …”
Publicado 2021
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
492“…Patients with insomnia become trapped in a vicious circle of bad moods and poor sleep. Resting-state functional magnetic resonance imaging (r-fMRI) studies have shown abnormalities in emotion-related brain networks in patients with ID. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
493“…To protect workers from the vicious circle of the poverty-health trap, national social protections such as sickness benefits are needed. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
494por Galffy, Matyas, Bichler, Carina, Mohr, Thomas, Egeter, Jonas, Neu, Leonie, Oberhammer, Maria, Högl, Birgit, Deisenhammer, Eberhard A., Sperner-Unterweger, Barbara, Hüfner, Katharina“…These videos explain, e.g., interactions of mental stress and the immune system or the vicious circle of anxiety. Additional videos provide easy to learn techniques like breathing and relaxation exercises. …”
Publicado 2022
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
495por Liu, Minhui, Peng, Wenting, Miyawaki, Christina E., Mo, Cen, Luo, Yuqian, Gong, Ni“…Homebound status and falls form a vicious circle and mutually reinforce each other over time. …”
Publicado 2022
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
496“…As a consequence, a vicious circle of the slowing down of the economic growth drives away working forces and quickens the pace of population ageing, is present. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
497por Abdallah, Ahmed B. E., El-Ghannam, Mohammed A., Hasan, Azza A., Mohammad, Lamiaa G., Mesalam, Noura M., Alsayed, Radwa M.“…Conclusively, SeNPs decreased androgen synthesis and blocked the vicious circle initiated by excessive androgen secretion via decreased AR expression. …”
Publicado 2023
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
498“…The ensuing calcium overload affects the mitochondria, cytoplasmatic metabolism and the endothelium which further worsens the energetic situation (vicious circle) to explain postexertional malaise, exercise intolerance and chronification. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
499por Kagaruki, Gibson B., Mayige, Mary T., Ngadaya, Esther S., Kilale, Andrew M., Kahwa, Amos, Shao, Amani F., Kimaro, Godfather D., Manga, Chacha M., Mbata, Doris, Materu, Godlisten S., Masumo, Ray M., Mfinanga, Sayoki G.“…The situation is worse when behavioral and biological risk factors are pervasive to PLHIV. Despite this vicious circle; information on the level of knowledge and perception regarding prevention of T2DM/HTN, risks factors and associated complications among PLHIV is not well documented in Tanzania. …”
Publicado 2018
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
500por Lundberg, Anna K., Chung, Rosanna W. S., Zeijlon, Louise, Fernström, Gustav, Jonasson, Lena“…BACKGROUND: Inflammation and oxidative stress form a vicious circle in atherosclerosis. Oxidative stress can have detrimental effects on T cells. …”
Publicado 2021
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto