“…The antiviral potency of PKR is emphasized by the number of strategies developed by viruses to antagonize the PKR pathway. In this review, we present an update on the diversity of such strategies, which range from preventing double-stranded RNA recognition upstream from PKR activation, to activating eIF2B downstream from PKR targets.…”
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“…The success of many viruses depends upon cooperative interactions between viral genomes. …”
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“…Importance of viruses for biotechnological processes.…”
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“…SIMPLE SUMMARY: Equine encephalosis (EE) is a febrile disease of horses caused by EE virus (EEV) and transmitted by Culicoides midges. …”
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“…Viruses are essentially, obligate intracellular parasites. …”
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“…Although, currently, at least seven viruses are being recognized as human carcinogens, only three of these – Epstein–Barr virus (EBV), human papillomavirus (HPV) and John Cunningham virus (JCV) – have been described, with varying levels of evidence, in CRC. …”
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“…Nipah virus (NiV) is a highly lethal zoonotic paramyxovirus that emerged in Malaysia in 1998. …”
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“…Viruses use diverse tactics to hijack host cellular machineries to evade innate immune responses and maintain their life cycles. …”
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“…Xenotransplantation may be associated with the transmission of potentially zoonotic porcine viruses. In order to prevent this, we developed highly sensitive PCR-based, immunologicals and other methods for the detection of numerous xenotransplantation-relevant viruses. …”
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“…Monkeypox is an uncommon viral zoonosis caused by the monkeypox virus (MPV), a member of the genus Orthopoxvirus. …”
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“…Currently, talimogene laherparepvec (T-VEC), a modified herpes virus, is FDA-approved in this population, with many other oncolytic viruses under investigation in both preclinical and trial settings. …”
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“…The numerous early and late endocrine complications reported during the current pandemic of coronavirus disease 2019 (COVID-19) reinforce the relevance of improving our understanding of the impact of viral infections on the endocrine system. Several viruses have been shown to infect endocrine cells and induce endocrine system disturbances through the direct damage of these cells or through indirect mechanisms, especially the activation of the host antiviral immune response, which may lead to the development of local or systemic inflammation or organ-specific autoimmunity. …”
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