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6401por Grazia Martina, Maria, Vicenti, Ilaria, Bauer, Lisa, Crespan, Emmanuele, Rango, Enrico, Boccuto, Adele, Olivieri, Noemi, Incerti, Matteo, Zwaagstra, Marleen, Allodi, Marika, Bertoni, Simona, Dreassi, Elena, Zazzi, Maurizio, van Kuppeveld, Frank J. M., Maga, Giovanni, Radi, Marco“…Their high mutation rate and rapid selection of resistance toward common antiviral drugs, together with the increasing number of co‐infections, make the war against viruses quite challenging. Herein we report a host‐targeted approach, based on the inhibition of the lipid kinase PI4KIIIβ, as a promising strategy for inhibiting the replication of multiple viruses hijacking this protein. …”
Publicado 2021
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6402por Mohsen, Fatema, Safieh, Homam, Shibani, Mosa, Ismail, Hlma, Alzabibi, Mhd Amin, Armashi, Humam, Sawaf, Bisher“…METHODS: A cross-sectional study was conducted at the Syrian Private University (SPU) in November 2019 on World Diabetes Day in Damascus, during the Syrian war crisis. Data were collected through self-administered questionnaires and analyzed using the Statistical Package for Social Sciences version 25.0 (SPSS Inc., United States). …”
Publicado 2021
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6403“…Despite therapeutic strategies including surgery, chemotherapy, and radiotherapy have been introduced into the war of fighting OS, the 5‐year survival rate for patients still remains unchangeable for decades. …”
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6404por Pausch, Markus“…Two essential agreements of the post-war period are increasingly being called into question: The European consensus, which considers European unification as an essential achievement and goal of political actors, and the democratic consensus, which states that representative democracy is the undisputed best form of government. …”
Publicado 2021
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6405“…Methods: We examine the mortality by year and month of birth of Belgians who had turned 100 during the current COVID-19 pandemic and whose birth fell on the years around the end the First World War and the outbreak of the H1N1 "Spanish flu" pandemic. …”
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6406por Alam, Faruq, Hossain, Rubina, Ahmed, Helal Uddin, Alam, Mohammad Tariqul, Sarkar, Mekhala, Halbreich, Uriel“…Since its harsh independence war, it has suffered from repeated floods and other natural and man-inflicted disasters. …”
Publicado 2021
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6407“…Modern medicine has been waging a war on cancer for nearly a century with no tangible end in sight. …”
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6408por Hui, Shalmali“…This disaster is the most polarising global pandemic after the World War II which causes significant economic, social, political disruption, and afflicts civilization throughout human history in the world. …”
Publicado 2021
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6409por Perelman, Sofya S., James, David B.A., Boguslawski, Kristina M., Nelson, Chase W., Ilmain, Juliana K., Zwack, Erin E., Prescott, Rachel A., Mohamed, Adil, Tam, Kayan, Chan, Rita, Narechania, Apurva, Pawline, Miranda B., Vozhilla, Nikollaq, Moustafa, Ahmed M., Kim, Sang Y., Dittmann, Meike, Ekiert, Damian C., Bhabha, Gira, Shopsin, Bo, Planet, Paul J., Koralov, Sergei B., Torres, Victor J.“…Altogether, this work advances our understanding of an important S. aureus toxin and underscores the importance of considering genetic variation to characterizing virulence factors and understand the tug of war between pathogens and the host.…”
Publicado 2021
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6410por Simão, Filipa, Ribeiro, Julyana, Vullo, Carlos, Catelli, Laura, Gomes, Verónica, Xavier, Catarina, Huber, Gabriela, Bodner, Martin, Quiroz, Alfredo, Ferreira, Ana Paula, Carvalho, Elizeu F., Parson, Walther, Gusmão, Leonor“…In addition to the remaining legacy of the colonial period, the joint analysis of the different types of markers included in this study revealed the impact of post-war migrations on the current genetic background of Paraguay.…”
Publicado 2021
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6411“…BACKGROUND: HIV (human immunodeficiency virus) and AIDS (acquired immunodeficiency syndrome) became a public issue in Libya after the infection of 400 children in El-Fatih Hospital in 1988. Due to the civil war, social and religious barriers, HIV prevalence is hard to establish, but it is generally believed to be increasing. …”
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6412Putin, der Cliotherapeut. Überdosis an Geschichte und politisierte Erinnerungskonflikte in Osteuropapor Gestwa, Klaus“…After briefly outlining the origins of civil society as well as the commercialisation and institutionalisation of historical interest in the post-Soviet countries, the article analyses the examples of the Russian-Estonian monument dispute as well as a dispute over the interpretation of the Second World War between Russia, Ukraine and Lithuania. The historical-political situation in Eastern Europe is characterised as a “battlefield of memories”.…”
Publicado 2021
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6413por Tillmar, Andreas, Sturk-Andreaggi, Kimberly, Daniels-Higginbotham, Jennifer, Thomas, Jacqueline Tyler, Marshall, Charla“…Five non-probative, previously identified World War II (WWII) cases were used to assess the kinship panel. …”
Publicado 2021
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6414por Tuli, Hardeep Singh, Sak, Katrin, Aggarwal, Poonam, Iqubal, Ashif, Upadhaya, Sushil K., Kaur, Jagjit, Kaur, Ginpreet, Aggarwal, Diwakar“…With nearly 4.92 million deaths by October 19, 2021, and serious health damages in millions of people, COVID-19 has been the most serious global challenge after the Second World War. Besides lost lives and long-term health problems, devastating impact on economics, education, and culture will probably leave a lasting impression on the future. …”
Publicado 2021
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6415“…Traumatic brain injury (TBI) is a major health concern, sometimes leading to long-term neurological disability, especially in children, young adults and war veterans. Although research investigators and clinicians have applied different treatment strategies or neurosurgical procedures to solve this health issue, we are still in need of an effective therapy to halt the pathogenesis of brain injury. …”
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6416“…Learning the regional differences and some special forms of trauma such as extreme sports, war, and gunshot injuries will help the prevention of the thoracolumbar spine fractures.…”
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6417“…The inception of cancer treatment with chemotherapeutics began in the 1940s with nitrogen mustards that were initially employed as weapons in World War II. Since then, treatment options for different malignancies have evolved over the period of last seventy years. …”
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6418por Soffer, Michal“…RESULTS: Three similar themes were identified in the samples: “the trivialization of cancer,” “cancer as metaphor,” and the “the war against cancer.” In both samples, people with cancer were depicted as heroic. …”
Publicado 2022
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6419“…Overall, there is good evidence for a tug-of-war between Mtb trying to limit inflammasome activation and the host cell trying to sense Mtb and activate the inflammasome. …”
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6420por Hughey, Matthew W.“…There is a great deal of survey-based, quantitative work that demonstrates a compelling case of White attitudinal polarization—a grouping of authoritarian, racist attitudes versus another alliance of progressive, antiracist attitudes—an increasingly racialized culture war. However, other studies, largely qualitative and open-ended, demonstrate the heterogeneous, shifting, and hypocritical nature of White discourse about race. …”
Publicado 2022
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