Mostrando 1 - 20 Resultados de 40 Para Buscar '"Wellcome Trust Sanger Institute"', tiempo de consulta: 1.31s Limitar resultados
  1. 1
    por Dooley, Erin E.
    Publicado 2006
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    EHPnet: Wellcome Trust Sanger Institute
  2. 2
    “…BACKGROUND: Increasingly large amounts of DNA sequencing data are being generated within the Wellcome Trust Sanger Institute (WTSI). The traditional file system struggles to handle these increasing amounts of sequence data. …”
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    Implementing a genomic data management system using iRODS in the Wellcome Trust Sanger Institute
  3. 3
    “…Two large-scale phenotyping efforts, the European Mouse Disease Clinic (EUMODIC) and the Wellcome Trust Sanger Institute Mouse Genetics Project (SANGER-MGP), started during the late 2000s with the aim to deliver a comprehensive assessment of phenotypes or to screen for robust indicators of diseases in mouse mutants. …”
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    Mouse large-scale phenotyping initiatives: overview of the European Mouse Disease Clinic (EUMODIC) and of the Wellcome Trust Sanger Institute Mouse Genetics Project
  4. 4
    Publicado 2002
    “…Hewlett-Packard has installed a supercomputer system valued at more than $22 million at the Wellcome Trust Sanger Institute (WTSI) in the U.K. HP has also joined the CERN openlab for DataGrid applications (1 page).…”
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    The company's mainframes join CERN's openlab for DataGrid apps and are pivotal in a new $22 million Supercomputer in the U.K.
  5. 5
    “…A report on the 'Genomic Disorders 2011 - The Genomics of Rare Diseases' meeting, Wellcome Trust Sanger Institute, Hinxton, UK, 23-26 March 2011…”
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    Massively parallel rare disease genetics
  6. 6
    por Bradbury, Jane
    Publicado 2003
    “…The Wellcome Trust Sanger Institute and Epigenomics AG recently announced the launch of the Human Epigenome Project - a 5-year project to map the sites of DNA methylation throughout the human genome…”
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    Human Epigenome Project—Up and Running
  7. 7
    por Dyke, Stephanie OM, Hubbard, Tim JP
    Publicado 2011
    “…The Wellcome Trust Sanger Institute has a strong reputation for prepublication data sharing as a result of its policy of rapid release of genome sequence data and particularly through its contribution to the Human Genome Project. …”
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    Developing and implementing an institute-wide data sharing policy
  8. 8
    “…All genes in LeishCyc are linked to the corresponding entry in GeneDB (Wellcome Trust Sanger Institute). CONCLUSION: The LeishCyc database describes Leishmania major genes, gene products, metabolites, their relationships and biochemical organization into metabolic pathways. …”
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    LeishCyc: a biochemical pathways database for Leishmania major
  9. 9
    por Ahmed, S.
    Publicado 2017
    “…Key participants include the Wellcome Trust Sanger Institute, EMB-EBI (EMBL-European Bioinformatics Institute), Open Targets and Elixir. …”
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    Embedding gender equality into institutional strategy
  10. 10
    “…The Vertebrate Genome Annotation (Vega) database (http://vega.sanger.ac.uk) was first made public in 2004 and has been designed to view manual annotation of human, mouse and zebrafish genomic sequences produced at the Wellcome Trust Sanger Institute. Since its initial release, the number of human annotated loci has more than doubled to close to 33 000 and now contains comprehensive annotation on 20 of the 24 human chromosomes, four whole mouse chromosomes and around 40% of the zebrafish Danio rerio genome. …”
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    The vertebrate genome annotation (Vega) database
  11. 11
    “…Availability: DNAPlotter is freely available (under a GPL licence) for download (for MacOSX, UNIX and Windows) at the Wellcome Trust Sanger Institute web sites: http://www.sanger.ac.uk/Software/Artemis/circular/ Contact: artemis@sanger.ac.uk…”
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    DNAPlotter: circular and linear interactive genome visualization
  12. 12
    “…Annotation tools that have been developed at the Wellcome Trust Sanger Institute (WTSI, http://www.sanger.ac.uk/.) are being used to fill that gap, as they can be used remotely and so open up viable community annotation collaborations. …”
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    Community gene annotation in practice
  13. 13
    “…Bill Skarnes is a Professor at Wellcome Trust Sanger Institute, United Kingdom.…”
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    2012 International Conference on Applied Biotechnology
  14. 14
    “…The zebrafish genome has recently been sequenced, the Zebrafish Mutation Project (launched by the Wellcome Trust Sanger Institute) has published the results of its first large-scale ethylnitrosourea (ENU) mutagenesis screen, and a host of new techniques, such as the genome editing technologies TALEN and CRISPR-Cas, are enabling specific mutations to be created in model organisms and investigated in vivo. …”
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    The emerging use of zebrafish to model metabolic disease
  15. 15
    “…Availability: Artemis is freely available (under a GPL licence) for download (for MacOSX, UNIX and Windows) at the Wellcome Trust Sanger Institute websites: http://www.sanger.ac.uk/resources/software/artemis/. …”
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    Artemis: an integrated platform for visualization and analysis of high-throughput sequence-based experimental data
  16. 16
    “…A Collaboration between the Wellcome Trust Sanger Institute and Cambridge University (Department of Medicine-Laboratory of Molecular Biology) has led to the creation of the zebrafish welfare terms from which standardization of terminology can be achieved.…”
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    Standardized Welfare Terms for the Zebrafish Community
  17. 17
    “…Informative SNPs were selected from the public SNP database at the Wellcome Trust Sanger Institute by comparing sequence data from C57BL/6NJ and C57BL/6J mice. …”
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    Development of SNP markers for C57BL/6N-derived mouse inbred strains
  18. 18
    “…Here we describe the Wellcome Trust Sanger Institute Genome Editing database (WGE), which uses novel methods to compute, visualize and select optimal CRISPR sites in a genome browser environment. …”
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    WGE: a CRISPR database for genome engineering
  19. 19
    “…A motivating case study utilizing a large scale high-throughput mouse phenotyping data set from the Wellcome Trust Sanger Institute Mouse Genetics Project, where the treatment is a gene ablation, demonstrates the benefits of the new pipeline on the downstream biological calls.…”
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    Improving the Identification of Phenotypic Abnormalities and Sexual Dimorphism in Mice When Studying Rare Event Categorical Characteristics
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    “…The resource provides a portal to genome sequence and annotation data, which is primarily generated by the Pathogen Genomics group at the Wellcome Trust Sanger Institute. It combines data from completed and ongoing genome projects with curated annotation, which is readily accessible from a web based resource. …”
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    GeneDB—an annotation database for pathogens
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