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641por Hur, Chin, Hayeck, Tristan J., Yeh, Jennifer M., Richards, Ethan B., Spechler, Stuart J., Gazelle, G. Scott, Kong, Chung Yin“…BACKGROUND: The incidence of esophageal adenocarcinoma (EAC) has risen rapidly in the U.S. and western world. The aim of the study was to begin the investigation of this rapid rise by developing, calibrating, and validating a mathematical disease simulation model of EAC using available epidemiologic data. …”
Publicado 2010
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642“…BACKGROUND: Colorectal cancer is one of the most common malignancies in the Western world. Screening and detection of its precursor lesion, the adenoma could prevent development of colorectal cancer. …”
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643por Heineke, Joerg, Auger-Messier, Mannix, Correll, Robert N., Xu, Jian, Benard, Matthew J., Yuan, Weiping, Drexler, Helmut, Parise, Leslie V., Molkentin, Jeffery D.“…Hypertrophic heart disease is a leading health problem facing the Western world. Here we identified the small EF-hand domain-containing protein CIB1 (Ca(2+) and integrin binding protein 1) in a screen for novel regulators of cardiomyocyte hypertrophy. …”
Publicado 2010
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644“…CONCLUSIONS: YACs in the western world seem to have comparable medical and psychosocial problems. …”
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645“…Atherosclerotic cardiovascular disease is the foremost cause of death and disability in the Western world, and it is rapidly becoming so in the developing nations. …”
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646“…Irritable bowel syndrome (IBS) is a chronic disorder that affects primarily female patients and is thought also to afflict approximately 7%–10% of the population of the Western World. Although bowel habits may change over the course of years, patients with IBS are characterized according to their predominant bowel habit, constipation (IBS-C), diarrhea (IBS-D), or mixed type (IBS-M), and treatments are focused toward the predominant symptom. …”
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647por Butt, Zubair M., Perlmutter, Adam E., Piacente, Pamela M., Wilding, Gregory, Tan, Wei, Kim, Hyung L., Mohler, James L., Guru, Khurshid A.“…BACKGROUND AND OBJECTIVES: Obesity is a major comorbidity in the Western world and influences outcomes of patient care. …”
Publicado 2008
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648“…The Western world appears to be in the midst of the third great gout epidemic of all time. …”
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649“…INTRODUCTION: The number of malpractice claims against physicians and health institutes is increasing continuously in Israel as in the rest of the Western world, and has become a serious financial burden. …”
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650por de Bakker, Jacob K., Nanayakkara, P. W. B., Geeraedts, L. M. G., de Lange, E. S. M., Mackintosh, M. O., Bonjer, H. J.“…BACKGROUND: The incidence of smuggling and transporting of illegal drugs by internal concealment, also known as body packing, is increasing in the Western world. The objective of this study was to determine the outcome of conservative and surgical approaches in body packers. …”
Publicado 2011
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651por Tassell, Mary C., Kingston, Rosari, Gilroy, Deirdre, Lehane, Mary, Furey, Ambrose“…The medicinal properties of hawthorn (Crataegus spp., a genus comprising approximately 300 species) have been utilized by many cultures for a variety of therapeutic purposes for many centuries. In the Western world cardiovascular disease (CVD) has become one of the single most significant causes of premature death. …”
Publicado 2010
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652por Henao-Mejia, Jorge, Elinav, Eran, Jin, Cheng-Cheng, Hao, Liming, Mehal, Wajahat Z., Strowig, Till, Thaiss, Christoph A., Kau, Andrew L., Eisenbarth, Stephanie C., Jurczak, Michael J., Camporez, Joao-Paulo, Shulman, Gerald I., Gordon, Jeffrey I., Hoffman, Hal M., Flavell, Richard A.“…Non-alcoholic fatty liver disease (NAFLD) is the hepatic manifestation of metabolic syndrome and the leading cause of chronic liver disease in the Western world. Twenty percent of NAFLD individuals develop chronic hepatic inflammation (non-alcoholic steatohepatitis, NASH) associated with cirrhosis, portal hypertension and hepatocellular carcinoma, yet causes of progression from NAFLD to NASH remain obscure. …”
Publicado 2012
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653por Cobiac, Linda J., Magnus, Anne, Lim, Stephen, Barendregt, Jan J., Carter, Rob, Vos, Theo“…BACKGROUND: Despite many decades of declining mortality rates in the Western world, cardiovascular disease remains the leading cause of death worldwide. …”
Publicado 2012
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654por Harrington, Daniel W., Elliott, Susan J., Clarke, Ann E., Ben-Shoshan, Moshe, Godefroy, Samuel“…Food allergies are emerging health risks in much of the Western world, and some evidence suggests prevalence is increasing. …”
Publicado 2012
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655“…BACKGROUND: A number of studies from the western world have explored the negative beliefs held by individuals towards people with mental illness. …”
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656por Azariah, Jayapaul“…There was a paradigm shift during industrial revolution in western world which culminated in modern science. The word “scientist” was coined during the 19th century. …”
Publicado 2009
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657“…The BSE epidemic peaked in 1992 and decreased thereafter; this decline is continuing sharply owing to intensive surveillance and screening programs in the Western world. However, there are still new outbreaks and/or progression of prion diseases, including atypical BSE, and iatrogenic CJD and vCJD via organ transplantation and blood transfusion. …”
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658“…Prostate cancer (PCa) is the most common malignancy, and the third leading cancer-related cause of death among men of the Western world. Upon PCa progression into metastatic disease, androgen deprivation therapy is applied as the first-line treatment, and has been shown to be effective in most patients, leading to a decrease in serum prostate-specific antigen and relief of disease-related symptoms. …”
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659por Wolf, Robert J., Hilger, Ralf A., Hoheisel, Jörg D., Werner, Jens, Holtrup, Frank“…Pancreatic cancer is one of the leading cancer-related causes of death in the western world with an urgent need for new treatment strategies. …”
Publicado 2013
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660“…Although there have been significant advances in the therapy of heart failure in recent decades, such as the introduction of β-blockers and antagonists of the renin–angiotensin–aldosterone system, this devastating disease still carries tremendous morbidity and mortality in the western world. G protein-coupled receptors, such as β-adrenergic and angiotensin II receptors, located in the membranes of all three major cardiac cell types, ie, myocytes, fibroblasts, and endothelial cells, play crucial roles in regulation of cardiac function in health and disease. …”
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