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1381por Ndreu, Lorena, Erber, Luke N., Törnqvist, Margareta, Tretyakova, Natalia Y., Karlsson, Isabella“…Approximately 20% of the general population in the Western world is affected by contact allergy. Although the importance of the hapten–protein conjugates is well established in the initiation of the immunological reaction, not much progress has been made regarding identification of these conjugates in vivo or exploration of their potential as diagnostic tools. …”
Publicado 2020
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1382por Devilliers, M.-J., Ben Hadj Salah, W., Barreau, E., Da Cunha, E., M’Garrech, M., Bénichou, J., Labetoulle, M., Rousseau, A.“…HSV-1 keratitis and kerato-uveitis affect approximately are the leading cause of infectious blindness in the Western world, mainly because of corneal opacification caused by recurrences. …”
Publicado 2021
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1383por Abid, Hakima, Alaoui, Moulaye El Hacen Horma Babana El, Lamrani, Moulay Youssef Alaoui, Figuigui, Mouna, Ahmed, Beiba Cheikh, Lahmidani, Nada, Yousfi, Mounia El, Benajah, Dafr-Allah, Maaroufi, Mustapha, Abkari, Mohammed El, Ibrahimi, Sidi Adil, Aqodad, Nourdin“…It is most common in Asia, accounting for only 20-30% of PAI in the Western world. Diagnosis is based on histological examination which shows dense lymphoplasmocytic infiltration in the organ affected associated with IgG4-positive plasma cells (immunohistochemistry), organ fibrosis and obliterating venulitis, all this in the context of increased serum IgG4 levels in more than 80% of cases. …”
Publicado 2020
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1384por Khondaker, Md. Tawkat Islam, Khan, Junaed Younus, Refaee, Mahmoud Ahmed, Hajj, Nady El, Rahman, M. Sohel, Alam, Tanvir“…Obesity is an emerging public health problem in the Western world as well as in the Gulf region. Qatar, a tiny wealthy county, is among the top-ranked obese countries with a high obesity rate among its population. …”
Publicado 2020
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1385por Barrett, Jack William“…INTRODUCTION: Traumatic brain injury (TBI) will be a leading cause of death and disability within the Western world by 2020. Currently, 80% of all TBI patients in England are transported to hospital by an ambulance service. …”
Publicado 2019
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1386por Santiago Pérez, María Isolina, López-Vizcaíno, Esther, Ruano-Ravina, Alberto, Pérez-Ríos, Mónica“…INTRODUCTION: The SARS-CoV-2 pandemic is the most important health challenge observed in 100 years, and since its emergence has generated the highest excess of non-war-related deaths in the western world. Since this disease is highly contagious and 33% of cases are asymptomatic, it is crucial to develop methods to predict its course. …”
Publicado 2021
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1387por Thoenes, Martin, Agarwal, Anurag, Grundmann, David, Ferrero, Carmen, McDonald, Andrew, Bramlage, Peter, Steeds, Richard P.“…Valvular heart disease (VHD) is a chronic progressive condition with an increasing prevalence in the Western world due to aging populations. VHD is often diagnosed at a late stage when patients are symptomatic and the outcomes of therapy, including valve replacement, may be sub-optimal due the development of secondary complications, including left ventricular (LV) dysfunction. …”
Publicado 2021
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1388por Schlecht, Anja, Zhang, Peipei, Wolf, Julian, Thien, Adrian, Rosmus, Dennis-Dominik, Boneva, Stefaniya, Schlunck, Günther, Lange, Clemens, Wieghofer, Peter“…Age-related macular degeneration (AMD) represents the most common cause of blindness in the elderly in the Western world. An impairment of the outer blood-retina barrier and a localized inflammatory microenvironment cause sprouting of choroidal neovascular membranes (CNV) in neovascular AMD that are in intimate contact with surrounding myeloid cells, such as retinal microglia, and ultimately lead to visual impairment. …”
Publicado 2021
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1389por Von Schulze, Alex T, Deng, Fengyan, Fuller, Kelly N Z, Franczak, Edziu, Miller, Josh, Allen, Julie, McCoin, Colin S, Shankar, Kartik, Ding, Wen-Xing, Thyfault, John P, Geiger, Paige C“…Nonacholic fatty liver disease, or hepatic steatosis, is the most common liver disorder affecting the western world and currently has no pharmacologic cure. …”
Publicado 2021
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1390por Naseraldeen, Naseba, Michelis, Regina, Barhoum, Masad, Chezar, Judith, Tadmor, Tamar, Aviv, Ariel, Shvidel, Lev, Litmanovich, Adi, Shehadeh, Mona, Stemer, Galia, Shaoul, Ety, Braester, Andrei“…Chronic lymphocytic leukemia (CLL) is the most common leukemia in adults in the western world. One of the treatments offered for CLL is immunotherapy. …”
Publicado 2021
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1391por Dönmez, Tugba, Höhne, Kerstin, Zissel, Gernot, Herrmann, Ken, Hautzel, Hubertus, Aigner, Clemens, Hegedüs, Balazs, Ploenes, Till“…Non-small cell lung cancer (NSCLC) is one of the most common malignancies in the western world [1]. Despite multiple therapeutic and diagnostic advances, the overall survival is low and recurrence of NSCLC is a common problem with different treatment regimens. …”
Publicado 2021
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1392por Stabellini, Nickolas, Krebs, Halle, Patil, Nirav, Waite, Kristin, Barnholtz-Sloan, Jill S.“…BACKGROUND: Gliomas are the most common type of primary malignant brain tumor in adults, representing one third of all primary and central nervous system (CNS) tumors and 80% of malignant tumors diagnosed in the Western world. Epidemiological data indicate that the overall incidence and mortality of cancer is higher in males, while females have a better prognosis. …”
Publicado 2021
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1393“…Colorectal cancer is a leading cause of death in the western world. The main datum that is employed to guide treatment and prognosis are related to the pathological stage and the genetics of the cancer. …”
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1394por Steffens, Daniel, Bramlage, Peter, Müller, Julia, Dorn, Cornelia, Paar, W Dieter, Scheeff, Celine, Kasner, Mario, Rauch-Kröhnert, U“…BACKGROUND: Atherosclerotic cardiovascular disease is the leading cause of death and disability in the Western world. OBJECTIVE: To characterise adults with confirmed coronary heart disease (CHD) and primary heterozygous familial or non-familial hypercholesterolaemia or mixed dyslipidaemia who received alirocumab in a real-world setting. …”
Publicado 2021
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1395por Steeds, Richard Paul, Potter, Andrew, Mangat, Navjeet, Fröhlich, Maren, Deutsch, Cornelia, Bramlage, Peter, Thoenes, Martin“…BACKGROUND: Degenerative aortic stenosis (AS), the most common valvular heart disease in the Western world, is often diagnosed late when the mortality risk becomes substantial. …”
Publicado 2021
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1396“…Heart failure (HF) remains the leading cause of morbidity and death in the western world, and new therapeutic modalities are urgently needed to improve the lifespan and quality of life of HF patients. …”
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1397por De Nisco, Giuseppe, Chiastra, Claudio, Hartman, Eline M. J., Hoogendoorn, Ayla, Daemen, Joost, Calò, Karol, Gallo, Diego, Morbiducci, Umberto, Wentzel, Jolanda J.“…Coronary atherosclerosis is a leading cause of illness and death in Western World and its mechanisms are still non completely understood. …”
Publicado 2021
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1398por Ursinus, Jeanine, Vrijmoeth, Hedwig D., Harms, Margriet G., Tulen, Anna D., Knoop, Hans, Gauw, Stefanie A., Zomer, Tizza P., Wong, Albert, Friesema, Ingrid H.M., Vermeeren, Yolande M., Joosten, Leo A.B., Hovius, Joppe W., Kullberg, Bart Jan, van den Wijngaard, Cees C.“…BACKGROUND: Concerns about long-lasting symptoms attributed to Lyme borreliosis (LB) are widespread in the Western world, while such symptoms are highly prevalent in the general population. …”
Publicado 2021
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1399por István, Lilla, Czakó, Cecilia, Benyó, Fruzsina, Élő, Ágnes, Mihály, Zsuzsa, Sótonyi, Péter, Varga, Andrea, Nagy, Zoltán Zsolt, Kovács, Illés“…Carotid artery stenosis (CAS) is among the leading causes of mortality and permanent disabilities in the Western world. CAS is a consequence of systemic atherosclerotic disease affecting the majority of the aging population. …”
Publicado 2021
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1400por TARAZONA, José Gabriel Rodríguez, ABDALLAH, Emne Ali, FLORES, Bianca de Cássia Troncarelli, BRAUN, Alexcia Camila, CAMILLO, Cláudia Malheiros Coutinho, MARCHI, Fabio Albuquerque, RUANO, Anna Paula Carreta, CHINEN, Ludmilla Thome Domingos“…Ductal adenocarcinoma of the pancreas is the fourth most common cancer-associated cause of death in the Western world. The presence of circulating tumor cells (CTCs) can be considered a potential prognostic factor, as these cells represent tumor progression, allowing monitoring of therapeutic efficacy. …”
Publicado 2022
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