The Qualification of an Enrichment Biomarker for Clinical Trials Targeting Early Stages of Parkinson’s Disease

por Stephenson, Diane, Hill, Derek, Cedarbaum, Jesse M., Tome, Maria, Vamvakas, Spiros, Romero, Klaus, Conrado, Daniela J., Dexter, David T., Seibyl, John, Jennings, Danna, Nicholas, Timothy, Matthews, Dawn, Xie, Zhiyong, Imam, Syed, Maguire, Paul, Russell, David, Gordon, Mark Forrest, Stebbins, Glenn T., Somer, Ed, Gallagher, Jill, Roach, Arthur, Basseches, Peter, Grosset, Donald, Marek, Kenneth
Publicado 2019

Repurposing human kinase inhibitors to create an antibiotic active against drug-resistant Staphylococcus aureus, persisters and biofilms

por Le, Philipp, Kunold, Elena, Macsics, Robert, Rox, Katharina, Jennings, Megan C., Ugur, Ilke, Reinecke, Maria, Chaves-Moreno, Diego, Hackl, Mathias W., Fetzer, Christian, Mandl, Franziska A. M., Lehmann, Johannes, Korotkov, Vadim S., Hacker, Stephan M., Kuster, Bernhard, Antes, Iris, Pieper, Dietmar H., Rohde, Manfred, Wuest, William M., Medina, Eva, Sieber, Stephan A.
Publicado 2019

DLG2 variants in patients with pubertal disorders

por Jee, Youn Hee, Won, Sehoon, Lui, Julian C., Jennings, Melissa, Whalen, Philip, Yue, Shanna, Temnycky, Adrian G., Barnes, Kevin M., Cheetham, Tim, Boden, Matthew G., Radovick, Sally, Quinton, Richard, Leschek, Ellen W., Aguilera, Greti, Yanovski, Jack A., Seminara, Stephanie B., Crowley, William F., Delaney, Angela, Roche, Katherine W., Baron, Jeffrey
Publicado 2020

Interhospital and interindividual variability in secondary prevention: a comparison of outpatients with a history of chronic coronary syndrome versus outpatients with a history of...

por Curneen, James MG, Judge, Conor, Traynor, Bryan, Buckley, Anthony, Saiva, Lavanya, Murphy, Laura, Murray, Donal, Fleming, Sean, Kearney, Peter, Murphy, Ross T, Aleong, Godfrey, Kiernan, Thomas J, O'Neill, James, Moore, David, Nicaodhabhui, Bridog, Birrane, John, Hall, Patricia, Crowley, James, Gibson, Irene, Jennings, Catriona S, Wood, David, Kotseva, Kornelia, McEvoy, John William
Publicado 2021

Dactinomycin induces complete remission associated with nucleolar stress response in relapsed/refractory NPM1-mutated AML

por Gionfriddo, Ilaria, Brunetti, Lorenzo, Mezzasoma, Federica, Milano, Francesca, Cardinali, Valeria, Ranieri, Roberta, Venanzi, Alessandra, Pierangeli, Sara, Vetro, Calogero, Spinozzi, Giulio, Dorillo, Erica, Wu, Hsin Chieh, Berthier, Caroline, Ciurnelli, Raffaella, Griffin, Melanie J., Jennings, Claire E., Tiacci, Enrico, Sportoletti, Paolo, Falzetti, Franca, de Thé, Hugues, Veal, Gareth J., Martelli, Maria Paola, Falini, Brunangelo
Publicado 2021

CD4 T cell dynamics shape the immune response to combination oncolytic herpes virus and BRAF inhibitor therapy for melanoma

por Bozhanova, Galabina, Hassan, Jehanne, Appleton, Lizzie, Jennings, Victoria, Foo, Shane, McLaughlin, Martin, Chan Wah Hak, Charleen ML, Patin, Emmanuel C, Crespo-Rodriguez, Eva, Baker, Gabby, Armstrong, Edward, Chiu, Matthew, Pandha, Hardev, Samson, Adel, Roulstone, Victoria, Kyula, Joan, Vile, Richard, Errington-Mais, Fiona, Pedersen, Malin, Harrington, Kevin, Ono, Masahiro, Melcher, Alan
Publicado 2022

Safer medicines To reduce falls and refractures for OsteoPorosis (#STOP): a study protocol for a randomised controlled trial of medical specialist-initiated pharmacist-led medicati...

por Moles, Rebekah Jane, Perry, Lin, Naylor, Justine M, Center, Jacqueline, Ebeling, Peter, Duque, Gustavo, Major, Gabor, White, Christopher, Yates, Christopher, Jennings, Matthew, Kotowicz, Mark, Tran, Thach, Bliuc, Dana, Si, Lei, Gibson, Kathryn, Basger, Benjamin Joseph, Bolton, Patrick, Barnett, Stephen, Hassett, Geraldine, Kelly, Ayano, Bazarnik, Barbara, Ezz, Wafaa, Luckie, Kate, Carter, Stephen Ross
Publicado 2023

Proteomic Network Analysis of Alzheimer’s Disease Cerebrospinal Fluid Reveals Alterations Associated with APOE ε4 Genotype and Atomoxetine Treatment

por Dammer, Eric B., Shantaraman, Anantharaman, Ping, Lingyan, Duong, Duc M., Gerasimov, Ekaterina S., Ravindran, Suda Parimala, Gudmundsdottir, Valborg, Frick, Elisabet A., Gomez, Gabriela T., Walker, Keenan A., Emilsson, Valur, Jennings, Lori L., Gudnason, Vilmundur, Western, Daniel, Cruchaga, Carlos, Lah, James J., Wingo, Thomas S., Wingo, Aliza P., Seyfried, Nicholas T., Levey, Allan I., Johnson, Erik C.B.
Publicado 2023

A Cross-Sectional Analysis of Body Composition Among Healthy Elderly From the European NU-AGE Study: Sex and Country Specific Features

por Santoro, Aurelia, Bazzocchi, Alberto, Guidarelli, Giulia, Ostan, Rita, Giampieri, Enrico, Mercatelli, Daniele, Scurti, Maria, Berendsen, Agnes, Surala, Olga, Jennings, Amy, Meunier, Nathalie, Caumon, Elodie, Gillings, Rachel, Kadi, Fawzi, Capel, Frederic, Cashman, Kevin D., Pietruszka, Barbara, Feskens, Edith J. M., De Groot, Lisette C. P. G. M., Battista, Giuseppe, Salvioli, Stefano, Franceschi, Claudio
Publicado 2018

Development of human cGAS-specific small-molecule inhibitors for repression of dsDNA-triggered interferon expression

por Lama, Lodoe, Adura, Carolina, Xie, Wei, Tomita, Daisuke, Kamei, Taku, Kuryavyi, Vitaly, Gogakos, Tasos, Steinberg, Joshua I., Miller, Michael, Ramos-Espiritu, Lavoisier, Asano, Yasutomi, Hashizume, Shogo, Aida, Jumpei, Imaeda, Toshihiro, Okamoto, Rei, Jennings, Andy J., Michino, Mayako, Kuroita, Takanobu, Stamford, Andrew, Gao, Pu, Meinke, Peter, Glickman, J. Fraser, Patel, Dinshaw J., Tuschl, Thomas
Publicado 2019

Pharmacodynamic Effects of Vorapaxar in Prior Myocardial Infarction Patients Treated With Potent Oral P2Y(12) Receptor Inhibitors With and Without Aspirin: Results of the VORA‐PRAT...

por Franchi, Francesco, Rollini, Fabiana, Faz, Gabriel, Rivas, Jose Ramon, Rivas, Andrea, Agarwal, Malhar, Briceno, Maryuri, Wali, Mustafa, Nawaz, Ahmed, Silva, Gabriel, Shaikh, Zubair, Maaliki, Naji, Fahmi, Kerolos, Been, Latonya, Pineda, Andres M., Suryadevara, Siva, Soffer, Daniel, Zenni, Martin M., Baber, Usman, Mehran, Roxana, Jennings, Lisa K., Bass, Theodore A., Angiolillo, Dominick J.
Publicado 2020

Improving rural health care reduces illegal logging and conserves carbon in a tropical forest

por Jones, Isabel J., MacDonald, Andrew J., Hopkins, Skylar R., Lund, Andrea J., Liu, Zac Yung-Chun, Fawzi, Nurul Ihsan, Purba, Mahardika Putra, Fankhauser, Katie, Chamberlin, Andrew J., Nirmala, Monica, Blundell, Arthur G., Emerson, Ashley, Jennings, Jonathan, Gaffikin, Lynne, Barry, Michele, Lopez-Carr, David, Webb, Kinari, De Leo, Giulio A., Sokolow, Susanne H.
Publicado 2020

Experimental Lagos bat virus infection in straw-colored fruit bats: A suitable model for bat rabies in a natural reservoir species

por Begeman, Lineke, Suu-Ire, Richard, Banyard, Ashley C., Drosten, Christian, Eggerbauer, Elisa, Freuling, Conrad M., Gibson, Louise, Goharriz, Hooman, Horton, Daniel L., Jennings, Daisy, Marston, Denise A., Ntiamoa-Baidu, Yaa, Riesle Sbarbaro, Silke, Selden, David, Wise, Emma L., Kuiken, Thijs, Fooks, Anthony R., Müller, Thomas, Wood, James L. N., Cunningham, Andrew A.
Publicado 2020

Genome-wide association study in individuals of European and African ancestry and multi-trait analysis of opioid use disorder identifies 19 independent genome-wide significant risk...

por Deak, Joseph D., Zhou, Hang, Galimberti, Marco, Levey, Daniel F., Wendt, Frank R., Sanchez-Roige, Sandra, Hatoum, Alexander S., Johnson, Emma C., Nunez, Yaira Z., Demontis, Ditte, Børglum, Anders D., Rajagopal, Veera M., Jennings, Mariela V., Kember, Rachel L., Justice, Amy C., Edenberg, Howard J., Agrawal, Arpana, Polimanti, Renato, Kranzler, Henry R., Gelernter, Joel
Publicado 2022

Polyamines and linear DNA mediate bacterial threat assessment of bacteriophage infection

por de Mattos, Camilla D., Faith, Dominick R., Nemudryi, Artem A., Schmidt, Amelia K., Bublitz, DeAnna C., Hammond, Lauren, Kinnersley, Margie A., Schwartzkopf , Caleb M., Robinson, Autumn J., Joyce, Alex, Michaels, Lia A., Brzozowski, Robert S., Coluccio, Alison, Xing, Denghui David, Uchiyama, Jumpei, Jennings, Laura K., Eswara, Prahathees, Wiedenheft, Blake, Secor, Patrick R.
Publicado 2023

Phase 1 study to determine the safety and dosing of autologous PBMCs modified to present HPV16 antigens (SQZ-PBMC-HPV) in HLA-A*02+ patients with HPV16+ solid tumors

por Jimeno, Antonio, Baranda, Joaquina, Iams, Wade T., Park, Jong Chul, Mita, Monica, Gordon, Michael S., Taylor, Matthew, Dhani, Neesha, Leal, Alexis D., Neupane, Prakash, Eng, Cathy, Yeku, Oladapo, Mita, Alain, Moser, Justin C., Butler, Marcus, Loughhead, Scott M., Jennings, Julia, Miselis, Nathan R., Ji, Rui-Ru, Nair, Nitya, Kornacker, Martin, Zwirtes, Ricardo F., Bernstein, Howard, Sharei, Armon
Publicado 2023

An ovine hepatorenal fibrocystic model of a Meckel-like syndrome associated with dysmorphic primary cilia and TMEM67 mutations

por Stayner, C., Poole, C. A., McGlashan, S. R., Pilanthananond, M., Brauning, R., Markie, D., Lett, B., Slobbe, L., Chae, A., Johnstone, A. C., Jensen, C. G., McEwan, J. C., Dittmer, K., Parker, K., Wiles, A., Blackburne, W., Leichter, A., Leask, M., Pinnapureddy, A., Jennings, M., Horsfield, J. A., Walker, R. J., Eccles, M. R.
Publicado 2017

Gender-specific association of body composition with inflammatory and adipose-related markers in healthy elderly Europeans from the NU-AGE study

por Santoro, Aurelia, Guidarelli, Giulia, Ostan, Rita, Giampieri, Enrico, Fabbri, Cristina, Bertarelli, Claudia, Nicoletti, Claudio, Kadi, Fawzi, de Groot, Lisette C. P. G. M., Feskens, Edith, Berendsen, Agnes, Brzozowska, Anna, Januszko, Olga, Kozlowska, Katarzyna, Fairweather-Tait, Susan, Jennings, Amy, Meunier, Nathalie, Caumon, Elodie, Napoli, Alessandro, Mercatelli, Daniele, Battista, Giuseppe, Capri, Miriam, Franceschi, Claudio, Bazzocchi, Alberto
Publicado 2019

The KDM5A/RBP2 histone demethylase represses NOTCH signaling to sustain neuroendocrine differentiation and promote small cell lung cancer tumorigenesis

por Oser, Matthew G., Sabet, Amin H., Gao, Wenhua, Chakraborty, Abhishek A., Schinzel, Anna C., Jennings, Rebecca B., Fonseca, Raquel, Bonal, Dennis M., Booker, Matthew A., Flaifel, Abdallah, Novak, Jesse S., Christensen, Camilla L., Zhang, Hua, Herbert, Zachary T., Tolstorukov, Michael Y., Buss, Elizabeth J., Wong, Kwok-Kin, Bronson, Roderick T., Nguyen, Quang-De, Signoretti, Sabina, Kaelin, William G.
Publicado 2019

Multi-Laboratory Comparison of Next-Generation to Sanger-Based Sequencing for HIV-1 Drug Resistance Genotyping

por Parkin, Neil T., Avila-Rios, Santiago, Bibby, David F., Brumme, Chanson J., Eshleman, Susan H., Harrigan, P. Richard, Howison, Mark, Hunt, Gillian, Ji, Hezhao, Kantor, Rami, Ledwaba, Johanna, Lee, Emma R., Matías-Florentino, Margarita, Mbisa, Jean L., Noguera-Julian, Marc, Paredes, Roger, Rivera-Amill, Vanessa, Swanstrom, Ronald, Zaccaro, Daniel J., Zhang, Yinfeng, Zhou, Shuntai, Jennings, Cheryl
Publicado 2020