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4por Trendafilova, Teodora, Adhikari, Kaustubh, Schmid, Annina B., Patel, Ryan, Polgár, Erika, Chisholm, Kim I., Middleton, Steven J., Boyle, Kieran, Dickie, Allen C., Semizoglou, Evangelia, Perez-Sanchez, Jimena, Bell, Andrew M., Ramirez-Aristeguieta, Luis Miguel, Khoury, Samar, Ivanov, Aleksandar, Wildner, Hendrik, Ferris, Eleanor, Chacón-Duque, Juan-Camilo, Sokolow, Sophie, Saad Boghdady, Mohamed A., Herchuelz, André, Faux, Pierre, Poletti, Giovanni, Gallo, Carla, Rothhammer, Francisco, Bedoya, Gabriel, Zeilhofer, Hanns Ulrich, Diatchenko, Luda, McMahon, Stephen B., Todd, Andrew J., Dickenson, Anthony H., Ruiz-Linares, Andres, Bennett, David L.“…Its electrophysiological correlate is “wind-up,” in which dorsal horn spinal neurons increase their response to repeated nociceptor stimulation. …”
Publicado 2022
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5por Taniguchi, Tomoya, Kinukawa, Tomoaki Alex, Takeuchi, Nobuyuki, Sugiyama, Shunsuke, Nishihara, Makoto, Nishiwaki, Kimitoshi, Inui, Koji“…Wind-up like pain or temporal summation of pain is a phenomenon in which pain sensation is increased in a frequency-dependent manner by applying repeated noxious stimuli of uniform intensity. …”
Publicado 2022
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7“…We compared FHR monitoring in labour using a novel, robust wind-up handheld Doppler with the Pinard as a primary screening tool for abnormal FHR on perinatal outcomes. …”
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8Publicado 1920Materias: “…The Winding-Up of a Nursing Association…”
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9Publicado 1920Materias: “…The Winding-Up of a Nursing Association…”
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10por Constandil, Luis, Hernández, Alejandro, Pelissier, Teresa, Arriagada, Osvaldo, Espinoza, Karla, Burgos, Hector, Laurido, Claudio“…Intrathecal IL-1β increased spinal cord wind-up activity in normal and monoarthritic rats without propentofylline pre-treatment, but resulted in decreased wind-up activity in normal and monoarthritic propentofylline-treated animals. …”
Publicado 2009
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11por Bravo, David, Zepeda-Morales, Katherine, Maturana, Carola J., Retamal, Jeffri S., Hernández, Alejandro, Pelissier, Teresa, Barra, Rafael, Sáez-Briones, Patricio, Burgos, Héctor, Constandil, Luis“…The results indicate that both NMDAR- and P2X7R-mediated increases in mechanical hyperalgesia and C-reflex wind-up potentiation require neuronal Panx1 channel activation to initiate and maintain nociceptive signaling in neuropathic rats.…”
Publicado 2022
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12“…The phenomenon of wind-up was dose-dependently reduced by gabapentin in neuropathy but not in normal and arthritic rats. …”
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13“…Exacerbations of acute pain can lead to neural sensitization and release of mediators both peripherally and centrally. Clinical wind up occurs from the processes of N-Methyl D-Aspartate (NMDA) activation, wind up central sensitization, long-term potentiation of pain (LTP), and transcription-dependent sensitization. …”
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14“…We recorded thresholds for pinprick and pressure pain, blink (BR) and nociceptive flexion reflex (NFR) R3 component coupled with wind-up ratios. Thresholds for pressure and pinprick pain, BR and NFR R3 were lower and wind-up ratios higher in patients. …”
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15por Slovák, Lukáš, Sarvestan, Javad, Iwatsuki, Takehiro, Zahradník, David, Land, William M., Abdollahipour, Reza“…Consequently, four phases of the volleyball spike including wind-up, cocking, acceleration, and follow-through were analyzed. …”
Publicado 2023
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16“…Both compounds decreased the wind-up activity in normal and monoarthritic rats. …”
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17“…The vertical stiffness of the parabolic leaf springs is related to the vehicle load-carrying capability, whereas the wind-up stiffness is associated with vehicle braking. …”
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18por D'Mello, Richard, Marchand, Fabien, Pezet, Sophie, McMahon, Stephen B, Dickenson, Anthony H“…This plasticity, such as “wind-up” and central sensitization, contributes to the hyperexcitability of dorsal horn neurons and increased pain-related behavior in animal models, as well as clinical signs of chronic pain in humans, hyperalgesia and allodynia. …”
Publicado 2011
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19“…Electrical thresholds for A and C fibre evoked activity, spike counts and wind-up characteristics at baseline and during RVM stimulation (10–100 µA, 10 Hz) were compared. …”
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20por Fukui, Tomokazu, Dai, Yi, Iwata, Koichi, Kamo, Hiroshi, Yamanaka, Hiroki, Obata, Koichi, Kobayashi, Kimiko, Wang, Shenglan, Cui, Xiuyu, Yoshiya, Shinichi, Noguchi, Koichi“…These observations indicate that ERK activation plays an important role in the induction of the wind-up responses in dorsal horn nociceptive neurons.…”
Publicado 2007
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