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  1. 30581
    “…A variety of features such as the previous number of ambulatory care visits, presence of ACSC-related hospitalisations during the observation window, age, rural residence and prescription of certain medications were contributors to the prediction. …”
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    Online Artículo Texto
    Predicting hospitalisations related to ambulatory care sensitive conditions with machine learning for population health planning: derivation and validation cohort study
  2. 30582
    “…RESULTS: WNT, RA, and FGF signaling promote the differentiation of hPSCs into SANLCs in a concentration- and time window-sensitive manner, respectively. Synergetic modulation of WNT, FGF, and RA signaling pathways enhance the pacemaker phenotype and improve the differentiation efficiency of SANLCs (up to 45%). …”
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    Chemically defined and small molecules-based generation of sinoatrial node-like cells
  3. 30583
    “…OBJECTIVE: This CardioTox Breast study aims to investigate the use of cardiac imaging, based on cardiac magnetic resonance and echocardiography, and to identify associated circulating biomarkers to assess early tissue changes in chemo-induced and radiation-induced cardiotoxicity in the time window of 12 months after the end of radiotherapy in patients with breast cancer. …”
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    Online Artículo Texto
    Early Detection of Cardiotoxicity From Systemic and Radiation Therapy in Patients With Breast Cancer: Protocol for a Multi-Institutional Prospective Study
  4. 30584
    “…Where dedicated Aerosol Generating Procedure (AGP) rooms were unavailable, clinicians resorted to window opening and variable room “down-time” between patients. …”
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    Online Artículo Texto
    COVID-VU – ENT-UK national survey of flexible nasendoscopy in the upper aerodigestive tract amidst the COVID-19 pandemic
  5. 30585
    “…The majority of the ADEs were preventable, indicating the existence of a window of opportunity to ensure patient safety. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s40360-022-00570-w.…”
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    Incidence of adverse drug events in patients hospitalized in the medical wards of a teaching referral hospital in Ethiopia: a prospective observational study
  6. 30586
    “…Finally, the number of banana plants was obtained by counting the number of pseudo-stems, and the diameter of pseudo-stems was measured using a cylindrical segmentation algorithm. A sliding window recognition method was proposed to determine the junction position between leaves and pseudo-stems, and the height of the pseudo-stems was measured. …”
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    Banana plant counting and morphological parameters measurement based on terrestrial laser scanning
  7. 30587
    por Park, Bo-yong, Larivière, Sara, Rodríguez-Cruces, Raul, Royer, Jessica, Tavakol, Shahin, Wang, Yezhou, Caciagli, Lorenzo, Caligiuri, Maria Eugenia, Gambardella, Antonio, Concha, Luis, Keller, Simon S, Cendes, Fernando, Alvim, Marina K M, Yasuda, Clarissa, Bonilha, Leonardo, Gleichgerrcht, Ezequiel, Focke, Niels K, Kreilkamp, Barbara A K, Domin, Martin, von Podewils, Felix, Langner, Soenke, Rummel, Christian, Rebsamen, Michael, Wiest, Roland, Martin, Pascal, Kotikalapudi, Raviteja, Bender, Benjamin, O’Brien, Terence J, Law, Meng, Sinclair, Benjamin, Vivash, Lucy, Kwan, Patrick, Desmond, Patricia M, Malpas, Charles B, Lui, Elaine, Alhusaini, Saud, Doherty, Colin P, Cavalleri, Gianpiero L, Delanty, Norman, Kälviäinen, Reetta, Jackson, Graeme D, Kowalczyk, Magdalena, Mascalchi, Mario, Semmelroch, Mira, Thomas, Rhys H, Soltanian-Zadeh, Hamid, Davoodi-Bojd, Esmaeil, Zhang, Junsong, Lenge, Matteo, Guerrini, Renzo, Bartolini, Emanuele, Hamandi, Khalid, Foley, Sonya, Weber, Bernd, Depondt, Chantal, Absil, Julie, Carr, Sarah J A, Abela, Eugenio, Richardson, Mark P, Devinsky, Orrin, Severino, Mariasavina, Striano, Pasquale, Parodi, Costanza, Tortora, Domenico, Hatton, Sean N, Vos, Sjoerd B, Duncan, John S, Galovic, Marian, Whelan, Christopher D, Bargalló, Núria, Pariente, Jose, Conde-Blanco, Estefania, Vaudano, Anna Elisabetta, Tondelli, Manuela, Meletti, Stefano, Kong, Xiang‐Zhen, Francks, Clyde, Fisher, Simon E, Caldairou, Benoit, Ryten, Mina, Labate, Angelo, Sisodiya, Sanjay M, Thompson, Paul M, McDonald, Carrie R, Bernasconi, Andrea, Bernasconi, Neda, Bernhardt, Boris C
    Publicado 2021
    “…Structural MRI has provided an in vivo window into whole-brain grey matter structural alterations in temporal lobe epilepsy relative to controls, by either mapping (i) atypical inter-hemispheric asymmetry; or (ii) regional atrophy. …”
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    Topographic divergence of atypical cortical asymmetry and atrophy patterns in temporal lobe epilepsy
  8. 30588
    “…In guinea pigs, NiRe-PPS-NP verified a quick penetration across the round window membrane and ATX-PPS-NP showed protective effect on spiral ganglion neurons, which further attenuated cisplatin-induced moderate hearing loss. …”
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    An enhanced antioxidant strategy of astaxanthin encapsulated in ROS-responsive nanoparticles for combating cisplatin-induced ototoxicity
  9. 30589
    “…This study supports inhibition of FXIa with milvexian as a promising antithrombotic therapy with a wide therapeutic window.…”
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    Milvexian, an orally bioavailable, small‐molecule, reversible, direct inhibitor of factor XIa: In vitro studies and in vivo evaluation in experimental thrombosis in rabbits
  10. 30590
    “…Here, we studied the dynamics of AFRs and TFRs and their responses to stand conditions and root density in a subtropical montane mixed forest based on a 2-a root window experiment. Mean (± SE) annual production, mortality, and turnover rate of AFRs were 7.87 ± 0.17 m m(−2) a(−1), 8.13 ± 0.20 m m(−2) a(−1)and 2.96 ± 0.24 a(−1), respectively, compared with 7.09 ± 0.17 m m(−2) a(−1), 4.59 ± 0.17 m m(−2) a(−1), and 2.01 ± 0.22 a(−1), respectively, for TFRs. …”
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    Effects of stand condition and root density on fine-root dynamics across root functional groups in a subtropical montane forest
  11. 30591
    “…With the recent FDA approval of aducanumab and more candidate drugs on the horizon, early identification of amyloid burden using quantitative measures is critical for enrolling appropriate subjects to help establish the optimal window for therapeutic intervention and secondary prevention. …”
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    Quantification of amyloid PET for future clinical use: a state-of-the-art review
  12. 30592
    “…CONCLUSION: Our results indicate a therapeutic window exists, which suggests that therapeutic drug monitoring of risperidone might increase safety and effectiveness in children and adolescents with ASD and behavioural problems.…”
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    Risperidone plasma concentrations are associated with side effects and effectiveness in children and adolescents with autism spectrum disorder
  13. 30593
    “…Here, we measure circulating concentrations of cardiac troponin T (cTNT), N-terminal pro-B-type natriuretic peptide (NT-proBNP) and growth differentiation factor 15 (GDF-15) during pregnancy—a window of time often referred to as a cardiovascular stress test for women. …”
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    Cardiovascular biomarkers in pregnancy with diabetes and associations to glucose control
  14. 30594
    “…Those with the highest baseline AJC demonstrated very slow response in this window and were less likely to be on concomitant methotrexate. …”
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    Latent classes of early response trajectories to biologics initiation in juvenile idiopathic arthritis: an analysis of four trials
  15. 30595
    “…Patients were indexed upon progression to CRPC and were followed until death or end of study period to assess frequency of monitoring with PSA tests and conventional imaging. A 2‐year look‐back window was used to assess patterns of care leading up to CRPC as well as baseline covariates. …”
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    Patterns of care for non‐metastatic castration‐resistant prostate cancer: A population‐based study
  16. 30596
    “…We used longitudinal Mendelian randomisation (MR) to determine whether there is a critical window during which BMI influences MS risk. METHODS: Summary statistics for childhood BMI (n ~ 28,000 children) and for MS susceptibility were obtained from recent large genome-wide association studies (GWAS) (n = 14,802 MS, 26,703 controls). …”
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    Age-specific effects of childhood body mass index on multiple sclerosis risk
  17. 30597
    “…Because we did not deplete ribosomal RNA, we have a unique window into AMR carried as ribosomal mutants. We show that AMR diversity varied between WTPs and that the relative abundance of many individual AMR genes/variants increased over time and may be connected to antibiotic use during the COVID-19 pandemic. …”
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    Longitudinal metatranscriptomic sequencing of Southern California wastewater representing 16 million people from August 2020–21 reveals widespread transcription of antibiotic resistance genes
  18. 30598
    “…Despite the availability of evidence, this window of opportunity remains unaddressed in many countries, including India. …”
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    Perceptions of and challenges faced by primary healthcare workers about preconception services in rural India: A qualitative study using focus group discussion
  19. 30599
    “…The strong synergistic interaction between COG1410 and polymyxin B dramatically reduced the working concentration of COG1410, expanding the safety window of the application. C. elegans infection model showed that combined therapy of COG1410 and polymyxin B was capable of significantly rescuing the infected nematodes. …”
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    Apolipoprotein E mimetic peptide COG1410 combats pandrug-resistant Acinetobacter baumannii
  20. 30600
    “…Our case–control analysis integrating population-based data from the GHS yielded no evidence of an increased risk after COVID-19 vaccination (OR = 0.93; 95% CI: 0.60–1.45, p = 0.75) in connection with a vaccination within a 4-week window. Conclusions: To date, there has been no evidence of any association between SARS-CoV-2 vaccination and a higher RVOD risk.…”
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    Retinal Vascular Occlusion after COVID-19 Vaccination: More Coincidence than Causal Relationship? Data from a Retrospective Multicentre Study
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