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  1. 30901
    “…Vaccination against covid-19 was treated as a time varying exposure in the outcome specific risk window, and propensity score weighting was used to adjust hazard ratios for potential confounding. …”
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    Risk of preterm birth, small for gestational age at birth, and stillbirth after covid-19 vaccination during pregnancy: population based retrospective cohort study
  2. 30902
    “…IL13Rα1, the other binding partner of IL13, is ubiquitously expressed in healthy tissue, raising concerns about the therapeutic window of systemic administration. IL13 mutants with diminished binding affinity to IL13Rα1 were previously generated by structure-guided protein engineering. …”
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    Engineered IL13 variants direct specificity of IL13Rα2-targeted CAR T cell therapy
  3. 30903
    “…Early treatment of RA within 3 months of symptom onset is associated with improved clinical outcomes. However, this window of opportunity is often missed. One important contributing factor is patients with symptoms of RA delaying consulting their general practitioner (GP). …”
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    The potential role of community pharmacy staff in reducing patient delay in consulting with symptoms of rheumatoid arthritis: a qualitative study
  4. 30904
    “…The understanding of the caregiver language at symptom onset sheds light on a critical window of often missed opportunity for earlier diagnosis and therapeutic intervention in MLD. …”
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    Understanding caregiver descriptions of initial signs and symptoms to improve diagnosis of metachromatic leukodystrophy
  5. 30905
    “…To this end, deafened guinea pigs received neurotrophic treatment in their right ear via a gelatin sponge on the perforated round window membrane, followed by cochlear implantation 4 weeks later in the same ear for electrophysiological recordings to various stimulation paradigms. …”
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    Combined brain-derived neurotrophic factor and neurotrophin-3 treatment is preferred over either one separately in the preservation of the auditory nerve in deafened guinea pigs
  6. 30906
    “…The long serial interval and low basic reproduction number might contribute to the observed slow progression of the pandemic, which gives a wide window of opportunities and time to control the spread. …”
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    An investigation of a hundred COVID-19 cases and close contacts in Ethiopia, May to June, 2020: A prospective case-ascertained study
  7. 30907
    “…CONCLUSION: Both protocols were able to accurately estimate (225)Ac-activities provided the francium-221 energy window was corrected for the down scatter of the higher-energy gamma-emissions by bismuth-213. …”
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    Gamma counting protocols for the accurate quantification of (225)Ac and (213)Bi without the need for a secular equilibrium between parent and gamma-emitting daughter
  8. 30908
    “…Onset and duration of newborns’ and mothers’ vocalizations and their temporal proximity within a 1-s time-window. RESULTS: In comparison with the Vertical group, very preterm newborns in the SDF Intervention Group spent less time in a drowsy state and more in deep sleep. …”
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    Skin-to-skin SDF positioning: The key to intersubjective intimacy between mother and very preterm newborn—A pilot matched-pair case-control study
  9. 30909
    “…CONCLUSION: The effect of rt-PA intravenous thrombolysis within the time window of patients with acute anterior circulation ischemic stroke is significant, but the ENI after thrombolysis is easily affected by the level of blood glucose; diabetes is the most important factor affecting the acute anterior circulation ischemic stroke patients Clinical factors of ENI after intravenous thrombolysis with rt-PA.…”
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    Analysis of influencing factors of early neurological improvement after intravenous rt-PA thrombolysis in acute anterior circulation ischemic stroke
  10. 30910
    “…We have identified a critical waiting window for cancer patients (or, immunocompromised subjects) to allow recovery of the immune system (particularly CD4+ T-cells) for effective differentiation of B-cells to produce neutralizing antibodies and thus achieve optimal vaccine efficacy against variants of concern, especially between the first and second doses. …”
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    A modeling-based approach to optimize COVID-19 vaccine dosing schedules for improved protection
  11. 30911
    “…CONCLUSION: Novel formulation of chitosan coated niosomes (chitosomes) could be presented as a promising platform to improve the oral bioavailability of drugs with narrow absorption window.…”
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    Novel Mucoadhesive Chitosomes as a Platform for Enhanced Oral Bioavailability of Cinnarizine
  12. 30912
    “…There is some evidence for serum cholesterol-lowering as an indirect mechanism linking statins with advanced and fatal prostate cancer. Window-of-opportunity clinical trials show measurable levels of statins in prostate tissue highlighting potential for direct effects, whilst observational data suggest possible statin-driven modulation of prostate microenvironment inflammation. …”
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    Statins and prostate cancer—hype or hope? The epidemiological perspective
  13. 30913
    “…Exclusion criteria were: valvular prosthesis; atrial fibrillation; cardiac transplantation; poor acoustic window. Median global PALS was 17% [24–32]. 29% of patients were in HF-stage 0/A, 35% in stage-B, and 36% in stage-C. …”
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    Left atrial strain determinants and clinical features according to the heart failure stages. New insight from EACVI MASCOT registry
  14. 30914
    “…TVCDS was conducted during the implantation window phase, and endometrial thickness, endometrial pattern, endometrial movement, blood flow type, and uterine and spiral arterial hemodynamic parameter measurements were made. …”
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    Endometrial microstimulation effects on endometrial receptivity assessed by transvaginal color Doppler sonography
  15. 30915
    “…BACKGROUND: Retinal changes are the window to systemic vasculature. Therefore, we explored retinal changes in patients with Idiopathic inflammatory myopathies (IIM) as a surrogate for vascular health. …”
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    Retinal changes in patients with idiopathic inflammatory myopathies: A case-control study in the MyoCite cohort
  16. 30916
    “…INTERPRETATION: Risk of HE in patients with lobar CAA‐ICH was not independently increased but seems to have different dynamics compared to other types of ICH. The time window for treatment of CAA‐ICH to prevent HE may be longer. …”
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    Cerebral Amyloid Angiopathy and the Risk of Hematoma Expansion
  17. 30917
    “…This provided a precious window to explore its effects on the spatio-temporal distribution of air pollution in Beijing, China. …”
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    Lockdown effects of the COVID-19 on the spatio-temporal distribution of air pollution in Beijing, China
  18. 30918
    “…Methods: We obtained 28 single nucleotide polymorphisms (SNPs) that were located within a ±15 kilobase window of the TNFRSF1A—the gene that encodes the TNFR1 protein, and we used genetic data from three GWAS studies of circulating levels of TNFR1, C-reactive protein (CRP), and white blood counts (WBC) to screen SNPs that proxied the inhibition of TNFR1. …”
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    Genetically proxied inhibition of tumor necrosis factor and the risk of colorectal cancer: A drug-target mendelian randomization study
  19. 30919
    “…Patients who missed this 7-month window had larger brain metastases (58% v 33% largest diameter > 10 mm; odds ratio, 2.80, CI, 0.51 to 13) versus those who had MRIs more frequently. …”
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    Predictive Model to Guide Brain Magnetic Resonance Imaging Surveillance in Patients With Metastatic Lung Cancer: Impact on Real-World Outcomes
  20. 30920
    “…The surveys were performed within a 4-day window under similar ambient conditions. We then compared the approaches in terms of feasibility, outcome and effort. …”
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    A pilot study to estimate the population size of endangered Galápagos marine iguanas using drones
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