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  1. 31281
    “…As a result, when VRC was coadministrated with glucocorticoids, the proportion of VRC C(min)/dose in the subtherapeutic window was increased. Different CYP450 genotypes have different effects on the C(min)/dose of VRC. …”
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    Interactive Effects of Glucocorticoids and Cytochrome P450 Polymorphisms on the Plasma Trough Concentrations of Voriconazole
  2. 31282
    “…These findings also hint towards a therapeutic window for targeting the early stages of α-synuclein pathology progression in this model, and potentially facilitate the discovery of mechanisms relevant to α-synuclein proteinopathies. …”
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    Prodromal neuroinvasion of pathological α-synuclein in brainstem reticular nuclei and white matter lesions in a model of α-synucleinopathy
  3. 31283
    “…Benefited from this bidirectional regulatory mechanism, MRPL52 is responsible for maintaining ROS levels in a window that can induce tumorigenic signal transduction without causing cytotoxicity in hypoxic breast cancer cells. …”
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    HIF-1-induced mitochondrial ribosome protein L52: a mechanism for breast cancer cellular adaptation and metastatic initiation in response to hypoxia
  4. 31284
    “…Our finding of extremely low success rates in those very young (under 6 years) and older (≥30 years) patients suggests that oocytes retrieved during OTC prior to chemotherapy have an optimal window of age that shows higher success rates, suggesting that oocytes may have an inherent tendency toward better maturation in those age groups.…”
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    Age-Dependent in vitro Maturation Efficacy of Human Oocytes – Is There an Optimal Age?
  5. 31285
    “…Dynamic FNC (dFNC) was investigated using a combination of a sliding window approach, clustering analysis, and graph analysis. …”
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    Online Artículo Texto
    Whole-Brain Functional Network Connectivity Abnormalities in Affective and Non-Affective Early Phase Psychosis
  6. 31286
    “…INTERPRETATION: The fact that most smokers start smoking regularly before age 20 years highlights the unique window of opportunity to target prevention efforts among young people and save millions of lives and avert health-care costs in the future. …”
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    Spatial, temporal, and demographic patterns in prevalence of smoking tobacco use and initiation among young people in 204 countries and territories, 1990–2019
  7. 31287
    “…While the primary analysis is offline, the nerve data is cut using a sliding window to create a “pseudo-online” dataset that resembles the conditions in a real-time paradigm. …”
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    Deep Learning-Based Approaches for Decoding Motor Intent From Peripheral Nerve Signals
  8. 31288
    “…Colonization offers a potential window of opportunity to intervene and prevent these infections, if the patients at greatest risk could be identified. …”
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    Online Artículo Texto
    Risk Factors for Klebsiella Infections among Hospitalized Patients with Preexisting Colonization
  9. 31289
    “…Patients with cerebral infarction are given routine treatments such as improving cerebral circulation, protecting nutrient brain cells, dehydration, and anti-platelet; patients with cerebral hemorrhage are treated within the corresponding safe time window. We use Statistical Product and Service Solutions (SPSS) Statistics21 software to perform statistical analysis on the results. …”
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    Monitoring and Prognostic Analysis of Severe Cerebrovascular Diseases Based on Multi-Scale Dynamic Brain Imaging
  10. 31290
    “…A more scattered IgM antibody reactivity across the viral proteome was observed in the acute phase of the disease and that persisted through the 6-month window. The magnitude, breadth (i.e. number of unique epitopes targeted) and depth (i.e. number of epitope variants recognized) of the IgG response was higher in secondary infections compared to primary infections. …”
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    Dynamics of the Magnitude, Breadth and Depth of the Antibody Response at Epitope Level Following Dengue Infection
  11. 31291
    “…Background: Stroke is the second leading cause of death in human life health, but current treatment strategies are limited to thrombolytic therapy, and because of the tight time window, many contraindications, and only a very small number of people can benefit from it, new therapeutic strategies are needed to solve this problem. …”
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    The Protective Effect of Liquiritin in Hypoxia/Reoxygenation-Induced Disruption on Blood Brain Barrier
  12. 31292
    “…Furthermore, we evaluated in vivo compatibility, biosafety and bone repair potential in a rat femur window defect model. 100M(+β)(-TCP) implants displayed a positive biosafety profile and showed significantly enhanced new bone formation compared to 100M implants evidenced by μCT (39 versus 25% bone volume/tissue volume ratio) and histological analysis 6 weeks post-implantation. …”
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    A Composite Lactide-Mineral 3D-Printed Scaffold for Bone Repair and Regeneration
  13. 31293
    “…In addition, highly informative SNPs with high MAF in each 500 kb sliding window and in each genic region were also included separately. …”
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    Validation of the Prediction Accuracy for 13 Traits in Chinese Simmental Beef Cattle Using a Preselected Low-Density SNP Panel
  14. 31294
    “…Our previous and present data consistently support the window effect of 980 nm, which has also been described in extracted mitochondria, through activation of signalling PI3K/Akt/Bcl-2 and cyclin family, while the Wnt and Smads 2/3-β-catenin pathway was induced by 55 J/cm(2), 0.9 W and 0.9 W/cm(2).…”
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    Photobiomodulation by Near-Infrared 980-nm Wavelengths Regulates Pre-Osteoblast Proliferation and Viability through the PI3K/Akt/Bcl-2 Pathway
  15. 31295
    “…However, the interpretation of the lanthanide maps acquired at the N(4,5) edge by the traditional 3‐window method, is complicated due to the broad shape of the edge profile and the lower signal‐above‐background ratio. …”
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    Elemental mapping of labelled biological specimens at intermediate energy loss in an energy‐filtered TEM acquired using a direct detection device
  16. 31296
    “…For each phase, the RMS of the sEMG signal amplitude was calculated and also normalized by a linear envelope (10-ms running RMS window). The muscle tension of the gastrocnemius decreased significantly during the loading response, initial swing, and terminal swing (p < 0.05), which helped the knee joint to get the maximum extension when the heel is on the ground and made the heel land smoothly. …”
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    Evaluation of Multilevel Surgeries in Children With Spastic Cerebral Palsy Based on Surface Electromyography
  17. 31297
    “…In this study, we investigated how Rapalink-1, a third-generation mTOR inhibitor, would affect neuronal survival and BBB disruption in the very early stage of cerebral ischemia–reperfusion that is within the time window of thrombolysis therapy. The middle cerebral artery occlusion (MCAO) was performed in rats under isoflurane anesthesia with controlled ventilation. …”
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    Rapalink-1 Increased Infarct Size in Early Cerebral Ischemia–Reperfusion With Increased Blood–Brain Barrier Disruption
  18. 31298
    “…More importantly, multifractal metrics obtained from hand movements behavior, beyond the confines of the brain, offer a window on the fine organization of control architecture, with high sensitivity to hand-related control behavior under specific constraints. …”
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    Fast Hand Movements Unveil Multifractal Roots of Adaptation in the Visuomotor Cognitive System
  19. 31299
    “…In the present investigation, comparative gel-free proteomics was used to study the response of C. cellulovorans to butanol challenge and understand the tolerance mechanisms activated in this condition. Sequential Window Acquisition of all Theoretical fragment ion spectra Mass Spectrometry (SWATH-MS) analysis allowed identification and quantification of differentially expressed soluble proteins. …”
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    Clostridium cellulovorans Proteomic Responses to Butanol Stress
  20. 31300
    “…The uses of timber constructions are very diverse—it is used for the production of exterior wall and roof constructions, window frames and doors, and it is used for dry as well as wet premises. …”
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    Possibilities of Useful Use of Glued Wooden Construction Residues
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