“…RESULTS: Activation of endometrial hexosamine biosynthetic pathway (HBP) caused elevated O-GlcNAcylation during the window of implantation, affecting endometrial cell function and embryo implantation. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Our behavior assay, spanning 90 min using 10 mM PTZ on 7 days post fertilization zebrafish, provides a broad window to observe anti-seizure drug efficacy. To compare our method with previously published data, we tested carbamazepine, lamotrigine, and topiramate, which have been tested in previous PTZ zebrafish assays. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…The current report provides novel insights into early-life diet-microbiota axis triggered by metabolic protein intervention and puts high emphasis on the time window and duration of dietary intervention in modulating lifelong performance of ruminants. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…The minimal oxygen saturation (minSpO(2)) was determined from the oxygen saturation curve under a subject-specific search window. Primary HR metrics such as maximal HR in response to minSpO(2) and respiratory event-specific HR variability were computed from the synchronized recordings. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…New diabetes medications within a six-month window of the initial FGM dispense date were also recorded. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…First generation antipsychotics exhibit a narrow therapeutic window compared to second generation antipsychotics with respect to these Extrapyramidal side effects. …”
Enlace del recurso
Enlace del recurso

“…However, breeding for new superior heat-tolerant genotypes has been challenging due to the narrow window of sensitivity, the unpredictable nature of heat stress, and its frequent co-occurrence with drought stress. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Stronger early activity was associated with reduced hippocampal activity and diminished BOLD signal in dACC and rDLPFC, suggesting that preempting retrieval reduced overall control demands. In the later window, dACC activity was larger, and effective connectivity analyses revealed robust communication from dACC to rDLPFC and from rDLPFC to hippocampus, which are tied to successful forgetting. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…The collected data were entered into EPI data version 4.2 and then exported into SPSS window version 22. Bivariate and multivariate analysis was undertaken and information was presented by using simple frequency tables and pie charts. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Notably, non-tumor bearing mice treated with GD2-directed CAR T cells quickly developed fatal neurotoxicity within 14 days, suggesting on-target/off-tumor effect of the CAR T cells and a very narrow therapeutic window in the brain. These data highlight the utility of titratable mRNA-based CAR T cell therapy for CNS tumors and establish GD2-directed mRNA CAR T cells as a safe and effective method for treating thalamic DMG.…”
Enlace del recurso
Enlace del recurso

“…Preclinical studies have shown that minocycline plus N-acetylcysteine have positive synergy resulting in therapeutic effects and a more prolonged therapeutic time window not seen with the individual drugs. This review compares the actions of minocycline and N-acetylcysteine, individually and in combination. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…The RDA was used to extract information from 47 DBZDs in 13,514 UHPLC-QTOF-MS data files from DUID cases analyzed from 2014 to 2020, with filters on the retention time window, count level, and mass error. Sixteen designer and uncommon benzodiazepines (DBZDs) were detected, where 47 identifications had been confirmed by using complementary methods when the case was open (confirmed positive finding), and 43 targets were not reported when the case was open (tentative positive finding). …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Common variable types include: 1) timepoint (specific time to represent when intake occurs, such as ‘breakfast time’); 2) duration/interval (length of time or interval when intake does/does not occur, such as ‘eating window’); and 3) distribution (proportion of daily intake at a given time interval, such as ‘% of energy before noon’). …”
Enlace del recurso
Enlace del recurso

“…CONCLUSION: We developed multistage prediction models and a risk screening strategy, biomarkers of which were part of routine test items and did not need extra costs. The prediction window has been advanced to 5–10 weeks, which has allowed time for aspirin intervention and other means for PE high-risk groups.…”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…DISCUSSION: We conclude that DEHP disrupted enamel development in mice by directly acting on dental cells with higher prevalence and severity in males than in females. The time window of DEHP effects on mouse tooth development led to typical alterations of structural, biochemical, and mechanical properties of enamel comparable to other EDCs, such as bisphenol A. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…All patients were recruited prior to treatment administration, at the maximum time-window following the previous dose. Interestingly, the severe/moderate patients had a similar TGT compared to the mild patients, reflecting the non-bleeding phase of our patient cohort, regardless of the initial diagnosis (i.e., the severity of the disease), treatment regime, and FVIII activity measured at the time of the TGT. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…BACKGROUND: Social media provide a window onto the circulation of ideas in everyday folk psychiatry, revealing the themes and issues discussed both by the public and by various scientific communities. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Patients tested for COVID-19 during the time window and not enrolled in HMP were included in the propensity-weighted comparison group. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Specifically, the d-fALFF was first acquired based on the sliding window method, whereas the gray matter map was computed based on voxel-based morphometry analysis. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…In various fixed time-window cohorts, the duration of PD treatment did not increase mortality risk after adjustments. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso