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  1. 31821
    “…MATERIALS AND METHODS: This study included (1) optimization of ICG dose and detection time-window for intracellular uptake by VX2 tumor cells; (2) in-vitro confirmation of capability of using ICG-based OI to assess efficacy of RFH-enhanced oncolytic therapy (LTX-401) for VX2 cells; and (3) in-vivo validation of the interventional OI-monitored, intratumoral RFH-enhanced oncolytic immunotherapy using rabbit models with orthotopic liver VX2 tumors. …”
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    Interventional Optical Imaging-Monitored Synergistic Effect of Radio-Frequency Hyperthermia and Oncolytic Immunotherapy
  2. 31822
    “…Zebrafish PDXs (zPDX) are nowadays emerging as a fast model allowing for multiple drugs to be tested at the same time in a clinically relevant time window. Here, we show that functional drug response profiling of zPDX from primary material obtained through the INdividualized Therapy FOr Relapsed Malignancies in Childhood (INFORM) pediatric precision oncology pipeline provides additional key information for personalized precision oncology. …”
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    Functional Therapeutic Target Validation Using Pediatric Zebrafish Xenograft Models
  3. 31823
    “…Physiological vitamin D levels for optimal immune function are considerably higher than those that can be achieved from food and sunlight exposure alone in Ireland. A window exists in which a significant number of adults could benefit from vitamin D supplementation, not least because of recent data demonstrating an association between vitamin D status and COVID-19. …”
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    Title: Understanding a Low Vitamin D State in the Context of COVID-19
  4. 31824
    “…CONCLUSION: This study contributes to limited evidence regarding the relationship between HAP exposure and blood pressure among women during pregnancy, a critical window for both mother and child's life-course health. …”
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    Online Artículo Texto
    Association between personal exposure to household air pollution and gestational blood pressure among women using solid cooking fuels in rural Tamil Nadu, India
  5. 31825
    “…Timing of opioid administration did not improve when compared to Phase I (Outside the window of efficacy: 42.1% vs. 43.8%, p = 0.903). Both patient (8.7 ± 2.4 vs. 7.7 ± 2.1; p = 0.011) and nurse (8.2 ± 2.1 vs. 7.3 ± 1.9; p = 0.021) satisfaction scores regarding pain control improved. …”
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    37 Procedural Pain Management in Burn Patients (Phase II) - A Quality Improvement Project
  6. 31826
    “…Cross-validation and hold out set testing was used, with performance over time evaluated through a rolling window approach. RESULTS: We included 8,100 patients recruited between 16th October 2010 and 10th December 2014. …”
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    The Diagnosis of Dengue in Patients Presenting With Acute Febrile Illness Using Supervised Machine Learning and Impact of Seasonality
  7. 31827
    “…OBJECTIVE: The purpose of this study was to clarify the influence of the vanishing twin (VT) on the perinatal outcomes in the surviving singleton and further identify the susceptible window. STUDY DESIGN: Retrospective cohort study. …”
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    The Influence of the Vanishing Twin on the Perinatal Outcome of Surviving Singleton in IVF Pregnancy
  8. 31828
    “…The dynamic changes of hallmark proteins at different time points after RIRI indicate that JAK-STAT signaling pathway activates rapidly but weakens later and plays a vital role in RIRI, and apoptosis is involved in RIRI with a peak value at 24 h in the process, suggesting a potential therapeutic direction and time window for treating RIRI.…”
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    Pathological Changes and Expression of JAK-STAT Signaling Pathway Hallmark Proteins in Rat Retinas at Different Time Points After Retinal Ischemia Reperfusion Injury
  9. 31829
    “…METHODS: Using ESM, 33 individuals, including 17 with CHR and 16 EP (age range: 15–24), provided information on substance use, negative affect, and psychotic symptoms 6 times a day across a 21-day data collection window. Psychotic symptoms and negative affect included multi-item variables rated on a seven-point Likert Scale. …”
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    Using Experience Sampling Methodology Data to Characterize the Substance Use of Youth With or At-Risk of Psychosis
  10. 31830
    “…This study aimed to fill the exploratory window on the long-term oncological safety of the video-laparoscopic versus open colorectal surgical approach in obesity. …”
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    Predictors of Long-Term Outcomes of Video-Laparoscopic Versus Open Surgery in Obese Patients with Colorectal Cancer: A Propensity Score Matching Study
  11. 31831
    por Rathod, Neelam, Chandorkar, Suneeta
    Publicado 2022
    “…Chrononutrition questionnaire assessed eating window, breakfast skipping, evening latency, evening eating, night eating, and largest meal of PWDs. …”
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    Low Glycaemic Meals Results in Greater Blood Glucose Spike in People With Diabetes Type 2 Following a Late Eating Pattern
  12. 31832
    “…A total mean of 701.48 ± 104.69 minutes spent eating window during work or school days and 646.67 ± 115.71 minutes used during free days. …”
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    What Is the Difference between the Nature Eating Rhythm and the Actual Eating Behaviors in Malaysian Adults? A Cross-Sectional Study of Circadian Misalignment
  13. 31833
    “…Pulsed ultrasound combined with microbubbles use can disrupt the blood–brain barrier (BBB) temporarily; this technique opens a temporal window to deliver large therapeutic molecules into brain tissue. …”
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    Influence of Acoustic Parameters and Sonication Schemes on Transcranial Blood–Brain Barrier Disruption Induced by Pulsed Weakly Focused Ultrasound
  14. 31834
    “…We show that the first week after hatching seems to be the critical window for ileal microbiota colonization and that a potentially stable microbiota has not yet been well established at 21 days of age. …”
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    Intestinal Immune Development Is Accompanied by Temporal Deviation in Microbiota Composition of Newly Hatched Pigeon Squabs
  15. 31835
    “…A key question remains whether early transcriptionally active microbial signature/s in COVID-19 patients can provide a window for future disease severity susceptibility and outcome? …”
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    Increased Abundance of Achromobacter xylosoxidans and Bacillus cereus in Upper Airway Transcriptionally Active Microbiome of COVID-19 Mortality Patients Indicates Role of Co-Infections in Disease Severity and Outcome
  16. 31836
    “…Facilitated axonal autophagosome retrograde transport by Sec22b knock-down and Ykt6 overexpression may reduce I/R-induced neuron injury and extend the therapeutic window of pharmacological autophagy induction for neuroprotection.…”
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    Unbalanced Regulation of Sec22b and Ykt6 Blocks Autophagosome Axonal Retrograde Flux in Neuronal Ischemia–Reperfusion Injury
  17. 31837
    “…Results of external validation in the overall time window (−/+21 days) showed area under receiver operating characteristic curves (AUC) of 0.70 when based only on MIR, 0.72 when based only on SCS, and 0.76 when based on both. …”
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    Prediction of Acute and Chronic Mastitis in Dairy Cows Based on Somatic Cell Score and Mid-Infrared Spectroscopy of Milk
  18. 31838
    “…Liquid biopsies detecting mutant cell-free DNA (cfDNA) provide a window of opportunity to attack mutant clones before they become clinically apparent. …”
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    Resistance to TKIs in EGFR-Mutated Non-Small Cell Lung Cancer: From Mechanisms to New Therapeutic Strategies
  19. 31839
    “…The overall current–voltage relationship of I(Na(T)) with or without the addition of CBZ remained unchanged; however, the strength (i.e., ∆area) in the window component of I(Na) (I(Na(W))) evoked by the short ascending ramp pulse (V(ramp)) was overly lessened in the CBZ presence. …”
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    Characterization in Inhibitory Effectiveness of Carbamazepine in Voltage-Gated Na(+) and Erg-Mediated K(+) Currents in a Mouse Neural Crest-Derived (Neuro-2a) Cell Line
  20. 31840
    “…Within these outbreaks, the serotypes O, A, SAT-2, and SAT-1 were identified in decreasing order of prevalence, respectively. When a window of 50% for the maximum temporal/space cluster size was set, a total of seven FMD clusters were identified in space and time. …”
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    Temporal and Spatial Patterns and a Space–Time Cluster Analysis of Foot-and-Mouth Disease Outbreaks in Ethiopia from 2010 to 2019
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