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  1. 31941
    “…Although the antitumor activity of (225)Ac-PSMA is well-documented, this treatment is nowadays only used as salvage therapy because the high incidence of xerostomia limits the therapeutic window. Thus, methods to reduce salivary toxicity and models able to describe xerostomia incidence are needed. …”
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    Online Artículo Texto
    Targeted Alpha Therapy in mCRPC (Metastatic Castration-Resistant Prostate Cancer) Patients: Predictive Dosimetry and Toxicity Modeling of (225)Ac-PSMA (Prostate-Specific Membrane Antigen)
  2. 31942
    por Imwong, Mallika, Dhorda, Mehul, Myo Tun, Kyaw, Thu, Aung Myint, Phyo, Aung Pyae, Proux, Stephane, Suwannasin, Kanokon, Kunasol, Chanon, Srisutham, Suttipat, Duanguppama, Jureeporn, Vongpromek, Ranitha, Promnarate, Cholrawee, Saejeng, Aungkana, Khantikul, Nardlada, Sugaram, Rungniran, Thanapongpichat, Supinya, Sawangjaroen, Nongyao, Sutawong, Kreepol, Han, Kay Thwe, Htut, Ye, Linn, Khin, Win, Aye Aye, Hlaing, Tin M, van der Pluijm, Rob W, Mayxay, Mayfong, Pongvongsa, Tiengkham, Phommasone, Koukeo, Tripura, Rupam, Peto, Thomas J, von Seidlein, Lorenz, Nguon, Chea, Lek, Dysoley, Chan, Xin Hui S, Rekol, Huy, Leang, Rithea, Huch, Cheah, Kwiatkowski, Dominic P, Miotto, Olivo, Ashley, Elizabeth A, Kyaw, Myat Phone, Pukrittayakamee, Sasithon, Day, Nicholas P J, Dondorp, Arjen M, Smithuis, Frank M, Nosten, Francois H, White, Nicholas J
    Publicado 2020
    “…In Myanmar a long pfkelch Phe446Ile haplotype has spread widely but, by contrast with the eastern Greater Mekong subregion, there is no indication of artemisinin combination therapy (ACT) partner drug resistance from genotyping known markers, and no evidence of spread of ACT resistant P falciparum from the east to the west. There is still a window of opportunity to prevent global spread of ACT resistance. …”
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    Molecular epidemiology of resistance to antimalarial drugs in the Greater Mekong subregion: an observational study
  3. 31943
    “…A composite treatment outcome (cTO) was used, defining success as viral load (VL) <200 copies/mL and failure as at least one of: VL ≥200 copies/mL, unknown VL in the time window, any changes of antiretroviral therapy (ART) regimen, AIDS, or death. …”
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    Virologic and immunologic outcomes of treatment with integrase inhibitors in a real-world setting: The RESPOND cohort consortium
  4. 31944
    “…METHODS: To identify potential IMI cases, we captured 2,363 positive fungal laboratory results, including cultures, histopathology, and galactomannan tests, within a 60-day window at three large Atlanta hospitals during April 2018–March 2019. …”
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    912. Beyond the Usual Suspects in Invasive Mold Infections: Public Health Surveillance Identifies Clinical Diversity
  5. 31945
    “…CONCLUSION: We note decreased transmission of influenza and RSV during a time window where widespread movement restrictions and social distancing were imposed to control COVID-19. …”
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    Online Artículo Texto
    484. The Impact of SARS-CoV-2 on Reproduction Rates of Seasonal Influenza and RSV
  6. 31946
    “…We extracted preoperative and intraoperative baseline factors and time-window of postoperative drainage fluid amylase and C-reactive protein-to-albumin ratio relevant to clinically relevant pancreatic fistula by performing univariate and multivariate analyses, developing a time-relevant logistic model with the evaluation of its discrimination ability. …”
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    Dynamic prediction for clinically relevant pancreatic fistula: a novel prediction model for laparoscopic pancreaticoduodenectomy
  7. 31947
    “…Exogenous administration of IL-1RA during this putative therapeutic window was able to suppress the hepatic APR, as evidenced by a reduction in CXCL1 and SAA-2 expression as well as a significant decrease in neutrophil infiltration in both the liver and the injured spinal cord itself. …”
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    Acute IL-1RA treatment suppresses the peripheral and central inflammatory response to spinal cord injury
  8. 31948
    “…METHODS: The present study analyzed resting-state functional magnetic resonance imaging data from 62 SCD patients, 75 MCI patients, and 70 healthy controls (HCs). We used the sliding-window and clustering method to identify two types of recurrent brain states from both dFC and dynamic regional spontaneous activity, as measured by dynamic fractional amplitude of low-frequency fluctuations (dfALFF). …”
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    Recurrent and concurrent patterns of regional BOLD dynamics and functional connectivity dynamics in cognitive decline
  9. 31949
    “…Our findings open a new window to the study of early tau pathology, with potential implications in early diagnosis and the design of therapeutic strategies. …”
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    Online Artículo Texto
    Tau-proximity ligation assay reveals extensive previously undetected pathology prior to neurofibrillary tangles in preclinical Alzheimer’s disease
  10. 31950
    “…Compared to 0L:24D group, the green light stimulation shortened the hatching time without extending the hatch window or impairing hatchability. The liver of embryos incubated in the 12L:12D light condition was heavier than those of the 0L:24D group on d 21 post incubation which may be linked to the observed increase in the serum concentration of insulin-like growth factor 1 (IGF-1); primary secretion of the liver. …”
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    Monochromatic green light stimulation during incubation shortened the hatching time via pineal function in White Leghorn eggs
  11. 31951
    “…CONCLUSIONS: These findings suggest that an intervention providing social and emotional experiential learning opportunities during the developmental window of very young adolescence can be effective in transforming gender norms, beliefs and behaviors. …”
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    Adolescent, caregiver and community experiences with a gender transformative, social emotional learning intervention
  12. 31952
    “…Assessments were conducted at 8 weeks (end of initial treatment block) and 6 months (end of window for retreatment). Feasibility was assessed by enrollment rate, treatment engagement, and completion of follow-up assessments. …”
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    Chronic care treatment for smoking cessation in patients with serious mental illness: a pilot randomized trial
  13. 31953
    “…Recently, EVT has been proven effective beyond the 6-h time window in a highly selected population using CT perfusion or MR diffusion. …”
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    MR CLEAN-LATE, a multicenter randomized clinical trial of endovascular treatment of acute ischemic stroke in The Netherlands for late arrivals: study protocol for a randomized controlled trial
  14. 31954
    “…The data were inserted into Epi-data version 3.1 and then exported into SPSS window version 20 for analysis. Bivariate and multivariate analyses were employed to identify the association between independent variables and the outcome variable. …”
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    Neonatal mortality among neonates admitted to NICU of Hiwot Fana specialized university hospital, eastern Ethiopia, 2020: a cross-sectional study design
  15. 31955
    “…The findings of this study indicate that at or soon after symptom onset represents the optimum time to test for SARS-CoV-2 in the URT, with median Ct values suggesting the useful testing window extends until around 15 days post-symptom onset. …”
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    Online Artículo Texto
    SARS-CoV-2 viral load dynamics and real-time RT-PCR cycle threshold interpretation in symptomatic non-hospitalised individuals in New Zealand: a multicentre cross sectional observational study
  16. 31956
    “…Measuring carotid artery velocity time integral (CAVTI) is easier, does not depend on adequate cardiac window, and requires less skill and expertise than LVOTVTI. …”
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    Efficacy of Left Ventricular Outflow Tract and Carotid Artery Velocity Time Integral as Predictors of Fluid Responsiveness in Patients with Sepsis and Septic Shock
  17. 31957
    “…The HDF maps were identified per 4-s window and an automated pattern recognition algorithm was used to find recurring HDF spatial patterns. …”
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    Online Artículo Texto
    Automatic Extraction of Recurrent Patterns of High Dominant Frequency Mapping During Human Persistent Atrial Fibrillation
  18. 31958
    “…This takes place during the mid-secretory phase of woman’s menstrual cycle and is a result of a delicate interplay between numerous hormones, cytokines and other factors. Outside of this window, the endometrium is refractory to an implanting blastocyst. …”
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    MAML1: a coregulator that alters endometrial epithelial cell adhesive capacity
  19. 31959
    “…CONCLUSIONS: Troponin and BNP were highly associated with urgent echocardiographic findings and may be used in triaging algorithms for determining in which patients TTE can be safely delayed until after their peak infectious window has passed.…”
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    Determining Which Hospitalized Coronavirus Disease 2019 Patients Require Urgent Echocardiography
  20. 31960
    “…Endocrine disruptors (EDs) interfere with hormonal signalling and, given that multiple developmental processes are hormone-driven, the prenatal period is a window of increased sensitivity. Maternal smoking is a real-life model of in utero exposure to a complex mixture of EDs. …”
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    Disruption of Estrogenic and Androgenic Bioactivities in Human Fetuses Exposed to Maternal Smoking
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