“…MATERIALS AND METHODS: 10–12-week-old CX3CR1+/GFP Thy1+/YFP mice on C57Bl6 background with normal hearing were fed chow containing 1200 mg/kg PLX5622 or control chow for the duration of the study. 7-days after starting the diet, 3-channel cochlear implants were implanted ear via the round window. Serial impedance and neural response telemetry (NRT) measurements were acquired throughout the study. …”
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“…Further analysis in a larger cohort may be warranted to validate these findings and explore use of open window mapping described elsewhere. [Figure: see text] [Figure: see text]…”
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“…This preparation, known as microsurgical graft or flap, is radically denervated by definition, but also effectively delays or even impedes the return of innervation for a significant period of time, thus creating a critical and therapeutic time window. Mammary adenocarcinoma cells (HH-16.cl4) were injected into immunocompetent Sprague Dawley adult rats. …”
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“…Since it may be sometimes difficult for these patients to access vaccination, hospitalization may be a window of opportunity to evaluate and offer vaccination. …”
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“…INTRODUCTION: The retina is the “window” of the central nervous system. Previous studies discovered that retinal thickness degenerates through the pathological process of the Alzheimer’s disease (AD) continuum. …”
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“…As such, environmental chemicals interfering with the activity of RXRs and their partners may have significant deleterious effects on human health, often in developmental window, cell-type, and gene selective ways. The frog Xenopus has long served as an excellent model for studying vertebrate development including thyroid hormone action, and recent advances in genome editing have greatly enhanced its utility for investigating basic cell and organismal biology as well as human disease processes. …”
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“…The postpartum period following a preeclamptic pregnancy is a unique window of opportunity to implement lifestyle changes targeted at reducing future maternal CVD. …”
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“…IV levothyroxine and hydrocortisone were started with improvement in her symptoms. A pericardial window was performed by the thoracic surgeon for her large pericardial effusion. …”
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“…However, they merely imposed limitations on Uisaengs’ operations—this policy loophole objectively left a window for Korean medicine merchants. Moreover, against the backdrop of the growing popularity of Western medicine and restrictions on the development of traditional Korean medicine by colonial authorities, the Korean herbal medicine industry, as one of the few “national industries” dominated by and serving Koreans, showed its tenacious vitality during that time. …”
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“…The dynamics of spontaneous brain activity were assessed using dynamic changes in the amplitude of low-frequency fluctuation (ALFF) with the sliding-window method. We used voxel-wise one-way analysis of variance (ANOVA) to compare dynamic ALFF variability among the three groups. …”
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“…Serum specimens and data were collected at the initial visit and 10 days later (cf, window of 6–17 days). Study participants with evidence, either clinical or laboratory, of possible myopericarditis were referred to a blinded independent review committee for further evaluation and adjudication. …”
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“…Early identification of ‘at risk’ individuals could provide a window of opportunity for preventing or delaying future diabetes and its long term complications. …”
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“…However, there is great variability in auditory performance and it remains unclear how auditory deprivation affects CI benefits within this 10-year window. This prospective study explores how measured auditory performance relates to real-world experience and device use in a cohort of SSD-CI subjects who have between 0 and 10 years of auditory deprivation. …”
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“…The intestinal micro-organisms of ruminants will gradually stabilize with weaning and growth and no longer change easily, so young age is a critical window to regulate the intestinal micro-organisms of ruminants. …”
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“…Identification of one or more organism involved in the PJI was also associated with revision during the study window (HR = 3.56, 95% CI: 1.94, 6.47), whereas elevated CRP was associated with lower rates of revision during the study period (HR = 0.21, 95% CI: 0.09, 0.46 for CRP >10 mg/L compared to CRP ≤10 mg/L). …”
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“…Individuals were categorized into 3 groups: ≥1 PrEP claim dispensed (DISP); never had PrEP dispensed with ≥50% of claims rejected by payer (ND-R); and never had PrEP dispensed with ≥50% of claims abandoned (ND-A). A 12-month window from the index (first PrEP claim submitted) was used to assess risk of HIV infection. …”
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“…Mean treatment duration was 176 days (range 20-326 days). 211 maintenance injections were administered during the study period; 16 (7.6%) were outside of the injection window with 10 (62.5%) oral bridges administered. …”
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“…TCS was done through a temporal bone window via a phased-array ultrasound using a 2.5 MHz transducer in a depth of 14–16 cm. …”
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“…The emission spectra of TCPP with a peak in the 645–700 nm window were obtained by calculation and subtraction based on the serial signal intensity (total flux) difference between (64)CuCl(2) + TCPP and (64)CuCl(2). …”
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“…CONCLUSIONS: Our analysis has formalized essential conditions for successful early detection of serous ovarian cancer. Although the window of opportunity for early detection of these cancers lasts for several years, developing a test sufficiently sensitive and specific to take advantage of that opportunity will be a challenge. …”
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