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  1. 821
    “…The unprecedented proliferation of recent large-scale and multi-omics databases of cancers has given us many new insights into genomic and epigenomic deregulation in cancer discovery in general. However, we wonder whether or not there exists a systematic connection between copy number aberrations (CNA) and methylation (MET)? …”
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    Multi-Omics Analysis Detects Novel Prognostic Subgroups of Breast Cancer
  2. 822
    “…Graphene, a wonder material, has made far-reaching developments in many different fields such as materials science, electronics, condensed physics, quantum physics, energy systems, etc. …”
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    Applications of Graphene and Graphene Oxide in Smart Drug/Gene Delivery: Is the World Still Flat?
  3. 823
    “…Because of this rapid increase in infected people scientists wonder whether SARS-CoV-2 was already highly circulating in Lombardy before such date. …”
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    Routine blood tests as an active surveillance to monitor COVID-19 prevalence. A retrospective study
  4. 824
    “…Opioid death rate (as a surrogate for prescription and illicit opioid use) was extracted from the CDCs Wonder online data through the Vital Statistics Cooperative Program. …”
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    Opioid use as a potential risk factor for pancreatic cancer in the United States: An analysis of state and national level databases
  5. 825
    “…These observations lead us to wonder whether MDSCs might not only exert an anti‐inflammatory effect but might also have direct influence on oligodendrocyte precursor cells (OPCs) and remyelination. …”
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    Myeloid‐derived suppressor cells support remyelination in a murine model of multiple sclerosis by promoting oligodendrocyte precursor cell survival, proliferation, and differentiation
  6. 826
    “…After the local government carried out furnace and stove reform work, lung cancer rate including incidence and mortality among residents remains high. We herein wonder if there are specific mechanisms at protein level for the development of non‐small‐cell lung cancer (NSCLC) in this area. …”
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    Dysregulation of ferroptosis may involve in the development of non‐small‐cell lung cancer in Xuanwei area
  7. 827
    “…The DFGs are here understood as generators of a more dialogic environment for girls in general and we wonder if and how It is extended to the context of girls with disabilities. …”
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    Dialogic Feminist Gathering and the Prevention of Gender Violence in Girls With Intellectual Disabilities
  8. 828
    “…CONCLUSION: It makes us wonder about other conditions of the patients. There is no standard COMP parameter to differentiate OA patients from colorectal cancer patients, but it considers the increase is higher in colorectal cancer patients. …”
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    Incidental Finding of Elevated Serum Cartilage Oligomeric Matrix Protein (sCOMP) in Knee Osteoarthritis Patient with Undiagnosed Colon Cancer: A Case Report
  9. 829
    “…Recent systematic reviews have found home-based rehabilitation to be as good as outpatient rehabilitation in terms of pain and physical function. We therefore wonder if physical rehabilitation “works” at all when compared to no physical rehabilitation after THA and TKA – “no rehabilitation” defined as no prescribed therapeutic rehabilitation exercises. …”
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    Physical rehabilitation versus no physical rehabilitation after total hip and knee arthroplasties: Protocol for a pragmatic, randomized, controlled, superiority trial (The DRAW1 trial)
  10. 830
    “…Because the number of patients with respiratory outcomes is high and there are few facilities available, we wonder if a spa setting could represent a valid out-of-hospital alternative. …”
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    Spa therapy interventions for post respiratory rehabilitation in COVID-19 subjects: does the review of recent evidence suggest a role?
  11. 831
    “…Based on these findings, it is possible to wonder if this kind of multisensory training would be an interesting therapy to not only improve communication but also help with posture and balance, cognitive abilities, and social participation. …”
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    Use of Music Therapy as an Audiological Rehabilitation Tool in the Elderly Population: A Mini-Review
  12. 832
    “…However, the mechanisms underlying their migration have not been fully understood. We wonder whether the voltage-gated proton channel HVCN1 in microglia/macrophages in the brain plays a role in their migration. …”
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    Neutralization of Hv1/HVCN1 With Antibody Enhances Microglia/Macrophages Myelin Clearance by Promoting Their Migration in the Brain
  13. 833
    “…Bearing clearly in the mind that pediatric and adult ACC patients represent different settings, we wonder whether there could be some areas of intervention overlapping to constitute a continuum of disease across ages. …”
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    Different management of adrenocortical carcinoma in children compared to adults: is it time to share guidelines?
  14. 834
    “…Its weakness is a failure to resolve a clinical quandary: patients appear for care individually, each may differ in important ways from an RCT cohort, and the physician will wonder each time if following EBM will provide best guidance for this unique patient. …”
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    Medicine-Based Evidence in Congenital Heart Disease: How Artificial Intelligence Can Guide Treatment Decisions for Individual Patients
  15. 835
    “…STUDY DESIGN AND METHODS: Lung cancer mortality data were extracted for males and females for each of the years 2000–2017 from the World Health Organization (WHO) Mortality and the Centers for Disease Control and Prevention (CDC) WONDER databases. Lung cancer mortality trends were compared using Joinpoint regression analysis, and male-to-female mortality ratios were calculated. …”
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    Lung cancer mortality in Europe and the USA between 2000 and 2017: an observational analysis
  16. 836
    “…Radix Ophiopogon Japonicus has long been used as traditional Chinese medicine to treat pulmonary disease, and Ophiopogonin B (OP-B) as a bioactive component of it has also been verified to inhibit cell proliferation of various non-small cell lung cancer (NSCLC) cells in vivo and in vitro. Therefore, we wonder whether OP-B is also effective to drug resistant lung cancer cells. …”
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    Ophiopogonin B alleviates cisplatin resistance of lung cancer cells by inducing Caspase-1/GSDMD dependent pyroptosis
  17. 837
    “…First, it strives to identify individuals that are unwilling to adhere to the vaccination process, more strongly question the effectiveness and necessity of the COVID-19 vaccine, and wonder about potential covert reasons for its administration. …”
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    Belonging to Socially Excluded Groups as a Predictor of Vaccine Hesitancy and Rejection
  18. 838
    “…East Kolkata Wetlands (EKW) a nature’s wonder where waste water fed natural aquaculture beltis is active for more than 70 years now and is efficiently operating as a natural waste management system. …”
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    Assessment of the bioaccumulation pattern of Pb, Cd, Cr and Hg in edible fishes of East kolkata Wetlands, India
  19. 839
    “…In uncertain and dynamic times, organisations wonder what skills make employees successful when working from home and which measures support employees. …”
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    Work from Home Success: Agile work characteristics and the Mediating Effect of supportive HRM
  20. 840
    “…Their experiences vary from feeling challenged and wonder how to get started, to feeling confident and taking initiatives that lead to ward-based improvements. …”
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    Role perception of infection control link nurses; a multi-centre qualitative study
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