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  1. 1921
    “…While Wnt5a only evoked brief Ca(2+) transients in immature neurons present in the intermediate zone (IZ), Wnt5a-induced Ca(2+) oscillations were sustained in neurons that migrated out to the cortical plate (CP). We wondered whether this early Wnt5a-Ca(2+) signaling during neuronal polarization has a morphogenetic consequence. …”
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    Facilitation of axon outgrowth via a Wnt5a-CaMKK-CaMKIα pathway during neuronal polarization
  2. 1922
    “…BACKGROUND: Chemokine CXC ligand 13 (CXCL13) has been implicated in perivascular inflammation and pulmonary vascular remodeling in patients with idiopathic pulmonary artery hypertension (IPAH). We wondered whether CXCL13 may also play a role in chronic thromboembolic pulmonary hypertension (CTEPH) and whether serum levels of CXCL13 might serve as biomarkers in these conditions. …”
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    CXCL13 in idiopathic pulmonary arterial hypertension and chronic thromboembolic pulmonary hypertension
  3. 1923
    “…Both glioma and infiltrating M/MΦ cells express the Ca(2+)-activated K(+) channel (KCa3.1), and the inhibition of KCa3.1 activity on glioma cells reduces tumor infiltration in the healthy brain parenchyma. We wondered whether KCa3.1 inhibition could prevent the acquisition of a pro-tumor phenotype by M/MΦ cells, thus contributing to reduce glioma development. …”
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    KCa3.1 inhibition switches the phenotype of glioma-infiltrating microglia/macrophages
  4. 1924
    “…As HCMV isolates, shortly after cultivation from clinical specimens, do not release cell-free infectious viruses, we wondered whether deletion of pUL74 would also affect virus growth in this background. …”
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    The contribution of pUL74 to growth of human cytomegalovirus is masked in the presence of RL13 and UL128 expression
  5. 1925
    “…We based the interviews on fictitious biographical vignettes to elicit responses and develop an understanding of social norms. We wondered whether, in trying to change norms, we might exploit the disjunction between descriptive norms (beliefs about what others actually do) and injunctive norms (beliefs about what others think one ought to do), focusing program activities on evidence that descriptive norms are changing. …”
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    You can’t burn the house down because of one bedbug: a qualitative study of changing gender norms in the prevention of violence against women and girls in an urban informal settlement in India
  6. 1926
    “…Members of the IMPACT-ME steering group, who brought their own experiences of depression and engaging with mental health services, were keen to find ways to provide information about depression and help-seeking beyond traditional academic audiences, specifically to other young people experiencing depression and wondering where to turn: their chosen medium was film. …”
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    Facing Shadows: working with young people to coproduce a short film about depression
  7. 1927
    por Wang, Duojin, Wu, Jing
    Publicado 2019
    “…In addition, we are also wondering how acceptable the respondents are on this matter. …”
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    Reprocessing and reuse of single-use medical devices in China: a pilot survey
  8. 1928
    “…Regulation of ERα signaling via its phosphorylation by growth factors is well recognized, and we wondered whether they could also trigger ERα methylation (mERα). …”
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    The arginine methyltransferase PRMT1 regulates IGF-1 signaling in breast cancer
  9. 1929
    “…The ventral midline thalamus (reuniens and rhomboid nuclei, ReRh) takes part in this transfer as its lesion disrupts systemic consolidation of spatial and contextual fear memories. Here, we wondered whether ReRh lesions would also affect the systemic consolidation of another type of memory, namely an olfaction-based social memory. …”
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    Ventral midline thalamus is not necessary for systemic consolidation of a social memory in the rat
  10. 1930
    “…Meteorological parameters and occurrences of cracking (CR), russeting (RS), and sun scald (SS) symptoms were monitored in a pomegranate cv. “Wonderful” orchard planted in a W–E orientation, during a 3-year study. …”
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    Physiological Disorders and Fruit Quality Attributes in Pomegranate: Effects of Meteorological Parameters, Canopy Position and Acetylsalicylic Acid Foliar Sprays
  11. 1931
    “…Co-evolution with the host immune system has provided SpA with an Fc-antibody binding site, and a Fab-binding site responsible for non-immune superantigen interactions via germline-encoded surfaces expressed on many human BCRs. We wondered whether the recurrent exposures to S. aureus commonly experienced by adults, result in the accumulation of memory B-cell responses to other determinants on SpA. …”
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    Diversity of Functionally Distinct Clonal Sets of Human Conventional Memory B Cells That Bind Staphylococcal Protein A
  12. 1932
    “…Participants differed in how they would handle the legal aspects of both cases, including whether and how to best follow mandated reporting policies. Providers wondered if they should report the husband in case study 1, the criteria for reporting, and where to report. …”
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    Clinical Care of Victims of Interpersonal Violence and Rape in Tanzania: A Qualitative Investigation
  13. 1933
    “…Because JNK is a key mediator of p53-induced apoptosis, we wondered if JNK/p53 pathway influences the effects of PF against apoptosis in mouse model of PD. …”
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    Paeoniflorin ameliorates cognitive impairment in Parkinson’s disease via JNK/p53 signaling
  14. 1934
    “…CONCLUSIONS: In France, a high-income country where prenatal follow-up is free, HPs were concerned that the CCT programme would change their relationship with patients and wondered if it was the best use of funding. However, women who received a cash incentive said they did not feel stigmatised and indicated that these payments helped them prepare for their baby’s birth. …”
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    Women and health professionals’ perspectives on a conditional cash transfer programme to improve pregnancy follow-up: a qualitative analysis of the NAITRE randomised controlled study
  15. 1935
    “…BACKGROUND: The administration of modified immune cells (MIC) before kidney transplantation led to specific immunosuppression against the allogeneic donor and a significant increase in regulatory B lymphocytes. We wondered how this approach affected the continued clinical course of these patients. …”
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    Five-year follow-up of a phase I trial of donor-derived modified immune cell infusion in kidney transplantation
  16. 1936
    por Deady, Joan
    Publicado 2004
    “…Recently released study results have left clinicians wondering if HRT should be used at all, and, if so, with whom and under what circumstances. …”
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    Clinical Monograph: Hormone Replacement Therapy
  17. 1937
    “…Considering associative memory deficits may presage preclinical AD, we wondered if one of the earliest changes might be in associative memory and whether younger women with BSO had changes similar to those observed in SM. …”
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    Women’s Brain Health: Midlife Ovarian Removal Affects Associative Memory
  18. 1938
    “…BACKGROUND: Integrins are closely related to mechanical conduction and play a crucial role in the osteogenesis of human mesenchymal stem cells. Here we wondered whether tensile stress could influence cell differentiation through integrin αVβ3. …”
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    Regulation of the integrin αVβ3- actin filaments axis in early osteogenic differentiation of human mesenchymal stem cells under cyclic tensile stress
  19. 1939
    “…Since alcohol intake by adult women consistently increases their breast cancer risk, we wondered whether maternal alcohol consumption during pregnancy increases female offspring's mammary tumorigenesis. …”
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    In utero alcohol exposure increases mammary tumorigenesis in rats
  20. 1940
    “…Recent studies have also shown that epigenetic silencing of microRNAs with tumor suppressor features by CpG island hypermethylation is a common hallmark of human tumors. Thus, we wondered whether there were other ncRNAs undergoing aberrant DNA methylation-associated silencing in transformed cells. …”
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    CpG island hypermethylation-associated silencing of non-coding RNAs transcribed from ultraconserved regions in human cancer
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