Mostrando 221 - 240 Resultados de 2,053 Para Buscar '"Writer"', tiempo de consulta: 0.16s Limitar resultados
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    “…RNAs are post-transcriptionally modified by dedicated writer or eraser enzymes that add or remove specific modifications, respectively. …”
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  6. 226
    por Fang, Runping, Ye, Lihong, Shi, Hui
    Publicado 2021
    “…Here we briefly outline the functions of m(6)A and its regulatory proteins, including m(6)A “writers,” “readers,” and “erasers” on RNA life fate, recapitulate the latest breakthroughs in understanding m(6)A modification and its regulatory proteins, and the underlying molecular mechanisms that contribute to the carcinogenesis and the progression of breast cancer, so as to provide potential epigenetic targets for diagnosis, treatment and prognosis in breast cancer.…”
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  7. 227
    por Kingori, Patricia
    Publicado 2021
    “…It pays attention to the Kenyan writers’ protestations that their knowledge, experiences and labour are all real and that analogies with shadows reduce them and the impact of their work to something that is non-existent and not alive. …”
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  8. 228
    por Ulatowska, Hanna, Olness, Gloria
    Publicado 2021
    “…The abrupt onset of stroke and associated aphasia, and the subsequent path toward re-engagement in life with an often-chronic communicative impairment, provide a unique window into the nature and evolution of the identity of the writer. The written modality offers an opportunity for reflective formulation that is not afforded to the memoir-writers in their verbal expression. …”
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  9. 229
    “…Abnormal changes in m(6)A levels are closely related to the regulation of RNA metabolism, heat shock stress, tumor occurrence, and development. m(6)A modifications are catalyzed by the m(6)A writer complex, which contains RNA methyltransferase-like 3 (METTL3), methyltransferase-like 14 (METTL14), Wilms tumor 1-associated protein (WTAP), and other proteins with methyltransferase (MTase) capability, such as RNA-binding motif protein 15 (RBM15), KIAA1429 and zinc finger CCCH-type containing 13 (ZC3H13). …”
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  10. 230
    por Cheng, Xu, Yi, Xuanzi
    Publicado 2023
    “…However, the potential role of RNA writers in prostate cancer is unclear. Methods: Based on data from three datasets, we describe 26 RNA writers that mediate gene expression and genetic mutation in prostate cancer and assess their expression patterns in 948 prostate cancer samples. …”
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  11. 231
    “…BACKGROUND: The five major RNA methylation modifications (m6A, m1A, m6Am, m5C, and m7G) exert biological roles in tumorigenicity and immune response, mediated mainly by “writer” enzymes. Here, the prognostic values of the “writer” enzymes and the TCP1 role in drug resistance in breast cancer (BC) were explored for further therapeutic strategies. …”
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  12. 232
    “…Here we review recent advances in our understanding of the structural biology of the writers, readers, and erasers of ADP-ribosylation.…”
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  13. 233
  14. 234
    por Weisz, George M.
    Publicado 2015
    “…This paper deals with the survival and suicides of Nazi-persecuted Jewish writers and offers a possible explanation for their late self-destructive acts.…”
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  15. 235
    “…These data demonstrate that PEITC regulates chromatin binding of key epigenetic writers/erasers and PcG complexes to restrict tumor development.…”
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    “…INTRODUCTION: Writer’s cramp (WC) as a focal hand dystonia is characterized by abnormal postures of the hand during writing. …”
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  18. 238
    “…Writer's cramp (focal hand dystonia) is a sporadic focal dystonia that affects a specific part of the upper limb causing excessive co-contraction of antagonistic muscles. …”
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  19. 239
    “…DNA modifications are incorporated by specific sets of enzymes—the writers—and the modified DNA-interacting partners—the readers—are ultimately responsible for maintaining a functional epigenetic landscape. …”
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  20. 240
    “…RNA modifications are dynamically controlled by the “writers, erasers, and readers”, where RNA modifying proteins are able to add, remove, and recognize specific chemical modification groups on RNAs. …”
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