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861por Li, Yu, Zhang, Yankang, Zhang, Ting, Ping, Xiaodan, Wang, Dongmei, Chen, Yanru, Yu, Jian, Liu, Caizhi, Liu, Ziqi, Zheng, Yuhan, Yang, Yongfeng, Ruan, Chengchao, Li, Dali, Du, Zhenyu, Wang, Jiqiu, Xu, Lingyan, Ma, Xinran“…Genetic ablation of m(6)A writer Mettl3 in fat tissues reveals that Mettl3 deficiency in mature beige adipocytes leads to suppressed glycolytic capability and thermogenesis, as well as reduced preadipocytes proliferation via glycolytic product lactate. …”
Publicado 2023
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862por Yardibi, Fatma, Chen, Chaomei, Fırat, Mehmet Ziya, Karacaören, Burak, Süzen, Esra“…VanRaden (2008) is the most cited work and has an essential place in the field. The most prolific writer is Ignacy Misztal. While the most productive country in breeding value studies is the United States, the People's Republic of China is an influential country that has experienced a strong citation burst in the last 3 years. …”
Publicado 2023
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863por Zinsser, Hans“…In this they differ from indifferent suspensions, like kaolin, which fix alexin and its fractions indiscriminately, fixing the end-piece without dependence upon previous adsorption of the mid-piece. The writer believes this to be of theoretical importance since it seems to show, in the first place, that the fixation of alexin by precipitates is not merely a mechanical adsorption, and in that it renders more likely the supposition that the so called precipitin is actually a protein sensitizer by which a foreign protein is rendered amenable to the proteolytic action of the alexin. …”
Publicado 1913
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864por Park, Edwards A.“…Extirpation of the thymus in the guinea pig produced no changes in the writer's experiments. 7. The study of the serial sections of the cervical tissues of the guinea pig indicates that Ruben's statements regarding the parathyroid derived from the fourth pharyngeal pouch in the guinea pig are correct,—that it is much smaller than parathyroid III, may be rudimentary, and is sometimes absent at least on one side. 8. …”
Publicado 1917
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865por Rosene, Hilda F.“…A micropotometric device previously described by the writer was used to determine quantitatively the velocity of water influx in cubic microns per square micron of hair surface per minute of comparatively older and younger root hairs of radish seedlings in a humid atmosphere at 29° ± 1°C. when the micropotometers were filled with Hoagland solution at pH 6.8. …”
Publicado 1950
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866por Autieri, Carmine, Kumar, P. Anil, Walecki, Dirk, Webers, Samira, Gubbins, Mark A., Wende, Heiko, Sanyal, Biplab“…Materials with high volume magnetization are perpetually needed for the generation of sufficiently large magnetic fields by writer pole of magnetic hard disks, especially for achieving increased areal density in storage media. …”
Publicado 2016
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867por Okuhara, Tsuyoshi, Ishikawa, Hirono, Okada, Masahumi, Kato, Mio, Kiuchi, Takahiro“…The included websites were classified as “anti”, “pro”, or “neutral” depending on the claims, and “health professional” or “non-health professional” depending on the writers. Readability was determined using a validated measure of Japanese readability. …”
Publicado 2016
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868“…Introduction: The successful “Divergent” sci-fi trilogy by writer Veronica Roth portrays a dystopian and post-apocalyptic society where the population is divided into five groups called “Factions,” each with a specific social role and associated to a specific set of psychological traits. …”
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869por Benito, E, Ramachandran, B, Schroeder, H, Schmidt, G, Urbanke, H, Burkhardt, S, Capece, V, Dean, C, Fischer, A“…The histone acetylation landscape is shaped by chromatin writer and eraser proteins, while readers link chromatin state to cellular function. …”
Publicado 2017
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870“…Post translational modifications (PTMs, e.g., phosphorylation, acetylation and methylation) of histone play important roles in regulating many fundamental cellular processes such as gene transcription, DNA replication and damage repair. While ‘writer’ and ‘eraser’ enzymes modify histones by catalyzing the addition and removal of histone PTMs, ‘reader’ proteins recognize these modified histones and ‘translate’ the PTMs by executing distinct cellular programs. …”
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871por Escher, Jill“…Given the urgency of the autism crisis, combined with the biological plausibility of this mostly unexplored paradigm, the writer contends that questions of nongenetic inheritance should be a priority in autism research.…”
Publicado 2018
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872por Kmietczyk, Vivien, Riechert, Eva, Kalinski, Laura, Boileau, Etienne, Malovrh, Ellen, Malone, Brandon, Gorska, Agnieszka, Hofmann, Christoph, Varma, Eshita, Jürgensen, Lonny, Kamuf-Schenk, Verena, Altmüller, Janine, Tappu, Rewati, Busch, Martin, Most, Patrick, Katus, Hugo A, Dieterich, Christoph, Völkers, Mirko“…Knockdown and overexpression of the m(6)A writer enzyme Mettl3 affected cell size and cellular remodeling both in vitro and in vivo. …”
Publicado 2019
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873“…The present article focuses on the background, scope, structure of a PADER, and its submission timelines; lists differences between PADER and PBRER; and describes the knowledge, skills, and attitudes required for a PADER writer.…”
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874por Courtney, David G., Chalem, Andrea, Bogerd, Hal P., Law, Brittany A., Kennedy, Edward M., Holley, Christopher L., Cullen, Bryan R.“…Consistent with a positive role for m(6)A and m(5)C in viral replication, we also demonstrate that overexpression of the key m(6)A reader protein YTHDF2 enhances MLV replication, while downregulation of the m(5)C writer NSUN2 inhibits MLV replication.…”
Publicado 2019
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875“…Up- and down-regulation of its “writer” or “eraser” proteins alter the global m(6)A level; however, modifying distinct m(6)A sites has remained elusive. …”
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876por Xie, Haiyun, Li, Jiangfeng, Ying, Yufan, Yan, Huaqing, Jin, Ke, Ma, Xueyou, He, Liujia, Xu, Xin, Liu, Ben, Wang, Xiao, Zheng, Xiangyi, Xie, Liping“…In this study, we demonstrated the tumour‐promoting function and specific regulatory mechanism of m(6)A axis, consisting of the core ‘writer’ protein METTL3 and the major reader protein YTHDF2. …”
Publicado 2020
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877por Mahgoub, Mohamed, Paiano, Jacob, Bruno, Melania, Wu, Wei, Pathuri, Sarath, Zhang, Xing, Ralls, Sherry, Cheng, Xiaodong, Nussenzweig, André, Macfarlan, Todd S“…In sum, our results indicate that the evolution of a dual histone methylation writer/reader (PRDM9/ZCWPW1) system in vertebrates remodeled genetic recombination hotspot selection from an ancestral static pattern near genes towards a flexible pattern controlled by the rapidly evolving DNA binding activity of PRDM9.…”
Publicado 2020
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878por Huang, Tao, Yuan, Shenli, Gao, Lei, Li, Mengjing, Yu, Xiaochen, Zhan, Jianhong, Yin, Yingying, Liu, Chao, Zhang, Chuanxin, Lu, Gang, Li, Wei, Liu, Jiang, Chen, Zi-Jiang, Liu, Hongbin“…The histone modification writer Prdm9 has been shown to deposit H3K4me3 and H3K36me3 at future double-strand break (DSB) sites during the very early stages of meiosis, but the reader of these marks remains unclear. …”
Publicado 2020
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879“…Using diffusion‐weighted imaging and graph theoretical analysis, we examined inter‐regional white matter connectivity of the whole‐brain structural network in two different forms of task‐specific focal dystonia, writer's cramp and laryngeal dystonia, compared to healthy individuals. …”
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880por Bhat, M Mohsin Alam“…This interview with writer and activist Harsh Mander was conducted on 21 and 23 April 2020 while numerous instances of hate crime, during the severe COVID-19 lockdown, were coming to light. …”
Publicado 2020
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