“…Mechanically, we showed that histone writer EP300 and WDR5 bind to circSOD2 promoter and trigger its promoter H3K27ac and H3K4me3 modification, respectively, which further activates circSOD2 expression. …”
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“…Java APIs:  In addition to Object and APIs related to exceptions, you explore Math, StrictMath, BigDecimal, BigInteger, String, StringBuffer/StringBuilder, Boolean, Character, Byte, Short, Integer, Long, Float, Double, Number, the Threads API, System, Runtime, Process, the Collections Framework, the Concurrency Utilities, Date, Formatter, Random, Scanner, the ZIP and JAR APIs, File, RandomAccessFile, stream classes, and writer/reader classes, InetAddress, SocketOptions, Socket, ServerSocket, DatagramSocket, MulticastSocket, URL, URLConnection, URLEncoder, URLDecoder, NetWorkInterface, InterfaceAddress, CookieHandler, CookieManager, CookieStore, CookiePolicy, Buffer, ByteBuffer, CharBuffer, DoubleBuffer,FloatBuffer, IntBuffer, LongBuffer, ShortBuffer, MappedByteBuffer, Channel, WritableByteChannel, ReadableByteChannel,ScatteringByteChannel, GatheringByteChannel, FileChannel, the Regular Expressions API, JDBC, and more. …”
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“…M6A related genes were selected from previous literatures, including "Writer" protein (METTL3, METTL5, METTL14, METTL16, ZC3H13, RBM15, WTAP, KIAA1429), "Reader" protein YTHDF1, YTHDF2, YTHDF3, YTHDC1, YTHDC2, HNRNPC, IGF2BP1, IGF2BP2, IGF2BP3), and "Eraser" protein (FTO, ALKBH5). …”
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“…This research analyzes what type of medicinal theory that the main writer Heo Joon employed in his real treatments, as well as how he diagnosed and treated diseases. …”
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“…But this holds true only when the inulin serum-water medium as modified by the writer is used. 13. A certain configuration of the colonies, designated by the term "ring-form," when present is diagnostic of the pneumococcus. 14. …”
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“…In the larvæ of salamanders these lesions find a definite expression in the permanent paralysis of almost the entire muscular system. In the writer's opinion, MacCallum's hypothesis that the tetany toxin has a special affinity for Ca, thereby diminishing the Ca content of the organism, cannot be disproved at present. …”
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“…The task ahead is cut out for each one of us: physician, patient, caregiver, biomedical researcher, writer/journalist, science administrator, policy maker, ethicist, man of religion, practitioner of alternate/complementary medicine, citizen of a world community, etc. …”
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“…We applied a topic modeling method to discover the themes in these Lynch syndrome–related tweets and conducted sentiment analysis on each layperson’s tweet to gauge the writer’s attitude (ie, positive, negative, and neutral) toward Lynch syndrome. …”
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“…Lindholm, MD, American Board of Internal Medicine (Individual(s) Involved: Self): Member of Auxiliary R&D Infectious Disease Item-Writer Task Force. No financial support received. …”
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“…METHODS: Global m(6)A levels and expressions of m(6)A writers, erasers and readers were evaluated by RNA methylation assay, dot blot, immunoblotting, immunohistochemistry and ELISA in human LUAD, mouse models and cell lines. …”
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“…However, the roles of both ac(4)C and its ‘writer’ protein N-acetyltransferase 10 (NAT10) played in the disease especially colorectal cancer (CRC) are unclear. …”
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“…Some proportion of cases, especially in young persons, will be found suitable for accurate determination of the question of whether all or most cases of severe diabetes are inevitably progressive and hopeless, and the writer looks forward to publishing such a series. …”
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“…Certain observations of the writer confirm this point. The experience of Alexander, Becke, and Holmes who exposed sensitized guinea pigs to sprays of dilute egg white with the result that 80 per cent of the animals developed symptoms of anaphylaxis, further strengthens the contention that certain of the membranes are readily permeable for the proteins of egg. …”
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“…Whether the R variants fall into sharply defined phases as pointed out by Leslie and Gardner, remains to be confirmed. Lawson and the writer have never noted their "Phase II" and Toomey (21) is in agreement with us that sharply defined, mutually exclusive subvarieties of R variants probably do not exist. …”
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“…Lindholm, MD, American Board of Internal Medicine (Individual(s) Involved: Self): Member of Auxiliary R&D Infectious Disease Item-Writer Task Force. No financial support received. …”
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“…Lindholm, MD, American Board of Internal Medicine (Individual(s) Involved: Self): Member of Auxiliary R&D Infectious Disease Item-Writer Task Force. No financial support received. …”
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“…In TAA-CCAs, G9a, an epigenetic pro-tumorigenic writer, was also increased. We show that EGFR signaling and mutant KRAS(G12D) can both activate IL6 production in CCA cells. …”
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“…He furthermore explains the fact that the subcutaneous L(+) dose remains the same whether the mixture is injected at once or after twenty-four hours, by assuming that in the subcutis of the guinea-pig there is a catalytic acceleration of the union of toxin and antitoxin. In view of the writer's results it seems that not only immediately, but four to five days after the preparation of the mixture of toxin and antitoxin, there are still toxic substances available for the production of immunity in the body of the guinea-pig, when the dose of toxin in the mixture is far below the L(0) or neutral level. …”
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“…RESEARCH METHODS: Following completion of the course, residents were encouraged to fill out a survey developed by the writer of the course designed to assess their thoughts about the course, their confidence in recognizing toxidromes as well as their comfort in the medical management of the poisoned patient. …”
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