“…This modification is regulated by three protein groups: methyltransferases (“writers”), demethylases (“erasers”), and m(6)A-binding proteins (“readers”). m(6)A modification and related enzymes could represent an optimal strategy to deepen the epigenetic mechanism. …”
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“…Based on previous publications of the writers, a quantitative method is given for the micro estimation of precipitin in the antisera to the dye. …”
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“…Such courses often harness the insights of established artists and writers in the illumination of medical themes. Less commonly students are called upon to link their own creative work with clinical and other life experience. …”
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“…Although both scenarios are highly undesirable, one can assume the magnitude of the effect of latter. Writers of scientific medical literature have been found to be involved in plagiarism and other publication misconducts from time to time irrespective of social, economic and geographic structure. …”
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“…Summary: The rapidly increasing research activity focused on chromatin-mediated regulation of epigenetic mechanisms is generating waves of data on writers, readers and erasers of the histone code, such as protein methyltransferases, bromodomains or histone deacetylases. …”
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“…In an effort to give more background to each of the above-mentioned cases, the writers have provided some details to aid comprehension. …”
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“…Avicenna was a Persian physician who is known as the most influential medical writers in the Middle ages. Avicenna`s Canon of Medicine, the most famous books in the history of medicine, presents a clear and organized summary of all the medical knowledge of the time, including a long list of drugs. …”
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“…Readers and writers of Spanish use an orthography that is highly transparent. …”
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“…This genetic modification machinery involves various writers, readers, and erasers that have unique structures, functions, and modes of action. …”
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“…In the postwar period, the area became notorious for vice, drugs and unsanitary living conditions, yet also attracted the attention of artists, photographers and writers, who viewed it as an instance of anarchic urbanism. …”
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“…Epigenetic regulators, including readers, writers, and erasers, are recurrently dysregulated by way of chromosomal translocations, somatic mutations, or genomic amplification in AML and many of these alterations are directly implicated in AML pathogenesis. …”
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“…In this review, we introduce the characteristics of m6A regulators, including “writers” that create m6A mark, “erasers” that show demethylation activity and “readers” that decode m6A modification to govern the fate of modified transcripts. …”
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“…The study included 21 eligible trials. Two writers extracted data at the same time independently. …”
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“…In this review, we discuss the specific roles of m(6)A "writers", "erasers", and "readers" in normal physiology and how their altered expression promotes tumorigenesis. …”
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“…Spectators frequently harass female soccer players, and women’s soccer is frequently compared negatively to men’s soccer by writers who make the comparison without the backing of any data and without taking into account anthropometric and physiological differences between the sexes. …”
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“…M(6)A modification is installed by the m(6)A methyltransferases (METTL3/14, WTAP, RBM15/15B and KIAA1429, termed as “writers”), reverted by the demethylases (FTO and ALKBH5, termed as “erasers”) and recognized by m(6)A binding proteins (YTHDF1/2/3, IGF2BP1 and HNRNPA2B1, termed as “readers”). …”
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“…As a dynamic and reversible modification, m(6)A is catalyzed by “writers” (RNA methyltransferases), removed by “erasers” (demethylases), and interacts with “readers” (m(6)A-binding proteins). …”
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“…The amount of m6A is determined by methylases (writers) and demethylases (erasers). The third type of proteins, readers, selectively bind to m6A to regulate RNA stability and gene expression. …”
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“…The dynamic equilibrium of m(6)A level is regulated by m(6)A methyltransferases (“writers”), m(6)A demethylases (“erasers”) as well as m(6)A-binding proteins (“readers”). …”
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“…N6-methyladenosine (m(6)A) is the most prevalent modification of mammalian cellular RNAs. m(6)A methylation is linked to epigenetic regulation of several aspects of gene expression, including RNA stability, splicing, nuclear export, RNA folding, and translational activity. m(6)A modification is reversibly catalyzed by methyltransferases (m(6)A writers) and demethylases (m(6)A erasers), and the dynamics of m(6)A-modified RNA are regulated by m(6)A-binding proteins (m(6)A readers). …”
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