“…We provide several lines of evidence that mRNA methylation of the adenine at this position, in combination with modified expression of m(6)A writers, acts to increase expression of CYP4C64 and resistance. …”
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“…Similar to chromatin-based epigenetic mechanisms, writers, readers, and erasers regulate both the presence and interpretation of these modifications, thereby adding further nuance to the control of gene expression. …”
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“…The platform should be readily transferable to further epitranscriptomic writers and erasers to manipulate epitranscriptomic marks in a programmable way with high molecular precision.…”
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“…N6-methyladenosine (m(6)A) methylation is one of the most common modifications of RNA in eukaryotic cells, and is mainly regulated by m(6)A methyltransferases (writers), m(6)A demethylases (erasers), and m(6)A binding proteins (readers). …”
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“…In this review, we give a general overview of the 12 main protein acylations (formylation, acetylation, propionylation, butyrylation, malonylation, succinylation, glutarylation, palmitoylation, myristoylation, benzoylation, crotonylation, and 2-hydroxyisobutyrylation), including their substrates (histones and nonhistone proteins), regulatory enzymes (writers, readers, and erasers), biological functions (transcriptional regulation, metabolic regulation, subcellular targeting, protein–membrane interactions, protein stability, and folding), and related diseases (cancer, diabetes, heart disease, neurodegenerative disease, and viral infection), to present a complete picture of protein acylations and highlight their functional significance in future research.…”
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“…N6-methyladenosine modification (m6A) fine-tunes RNA fate in a variety of ways, thus regulating multiple fundamental biological processes. m6A writers bind to chromatin and interact with RNA polymerase II (RNAPII) during transcription. …”
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“…The corpus-based quantitative analyses found that academic writers’ geo-academic location was a robust predictor of authors’ overall use of interest markers and some frame elements associated with the Interest frame. …”
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“…RNA modification and splicing are regulated by RNA methylation regulators called ‘writers’ (methyltransferases), ‘erasers’ (demethylases) and ‘readers’ (modified RNA-binding proteins). …”
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“…In this review, we first briefly summarize the latest advances in RNA m(6)A biology by focusing on writers, readers, and erasers of m(6)A modification, and describe the development of high-throughput methods for RNA m(6)A mapping. …”
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“…Classic works by Bolzano, Riemann, Hamilton, Dedekind, and Poincare are reproduced in reliable translations and many selections from writers such as Gauss, Cantor, Kronecker and Zermelo are here translated for the first time. …”
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“…This book is the result of various efforts to study the way in which these themes have reached literature and have become an object of reflection or aesthetic inquiry for many Latin American writers. Violence. Aesthetic representations is a book in search of first definitions, which explores the different discursive modalities -from poetry to drama, passing through the memoirs or the testimony genre; it proposes methodologies of analysis and invites us to reread a literary corpus that has portrayed these quests for freedom, pacification and civility, with the purpose of beginning to articulate a response to the problems that still define the territories of Mexico and Latin America.…”
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“…Encouraged by more mainstream publications by Caroline Furness Jansen (2008) and Kathleen Haddon (1930), over the course of the 20th century the string figure would become a model through which largely western writers and artists have explored both the anxieties and dreams of ideal, embodied and networked communication technologies. …”
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“…The analysis offered in this article demonstrates the integral importance of religion to Hakluyt's geographic work while simultaneously locating him within a wide continental network of theologians and writers to reassess the impact and reach of his ministerial role.…”
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“…Divergent N(6)-methyladenosine (m(6)A) modifications are dynamic and reversible posttranscriptional RNA modifications that are mediated by m(6)A regulators or m(6)A RNA methylation regulators, i.e., methyltransferases (“writers”), demethylases (“erasers”), and m(6)A-binding proteins (“readers”). …”
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“…The most widely affected RNA modification is m(6)A, whose writers, readers, and erasers all have regulatory effects on RNA localization, splicing, translation, and degradation. …”
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“…To achieve this, the article draws on ideas from some key Queer theorical writers, existing studies of queer aging and illustrates theoretical points with qualitative data collected from two LGBTQ+ projects to illustrate. …”
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“…Comparisons are made with the results of other writers. These compressional forces caused the poles of a severed anaphase spindle to move toward each other and the center of the cell. …”
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“…To date, successful efforts have been limited to chromatin modifying enzymes, or so-called epigenetic “writers” and “erasers”. Potent inhibitors of histone binding modules have not yet been described. …”
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“…Histone acetylation, one of the first and best studied histone post-translational modifications (PTMs), as well as the factors involved in its deposition (writers), binding (readers) and removal (erasers), have been shown to act at the heart of regulatory circuits controlling essential cellular functions. …”
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“…The results show that developing writers’ ability to make online revisions in creative writing tasks is related to both the quality of the final written product and to individual literacy skills. …”
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