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  1. 1601
    “…Its consortium organized a “Writers' Conference” in The Hague, The Netherlands at Europol's Headquarters where a group of 40 experts, consisting of transplant professionals, law enforcement officials, and policy makers, formulated recommendations to improve nonlegislative responses. …”
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    The Hague Recommendations: Improving Nonlegislative Responses to Trafficking in Human Beings for the Purpose of Organ Removal
  2. 1602
    “…DNA methyltransferases (Dnmts) - epigenetic writers catalyzing the transfer of methyl-groups to cytosine (DNA methylation) – regulate different aspects of memory formation in many animal species. …”
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    DNA methylation mediates neural processing after odor learning in the honeybee
  3. 1603
    “…ADP-ribosylation is a posttranslational modification that exists in monomeric and polymeric forms. Whereas the writers (e.g. ARTD1/PARP1) and erasers (e.g. PARG, ARH3) of poly-ADP-ribosylation (PARylation) are relatively well described, the enzymes involved in mono-ADP-ribosylation (MARylation) have been less well investigated. …”
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    Proteomic analyses identify ARH3 as a serine mono-ADP-ribosylhydrolase
  4. 1604
    “…With the development of antibody-based sequencing technologies and the findings of m6A-related “writers”, “erasers”, and “readers”, the relationships between m6A and mRNA metabolism are emerging. …”
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    N6-methyladenosine links RNA metabolism to cancer progression
  5. 1605
    “…A number of chromatin signatures, such as histone modifications, DNA methylation, chromatin accessibilities, and interactions, have been profiled at the genome level and analyzed in various murine and human thermogenic fat cell systems. Moreover, writers and erasers, as well as readers of the epigenome are also investigated using genomic tools in thermogenic adipocytes. …”
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    Epigenomic Control of Thermogenic Adipocyte Differentiation and Function
  6. 1606
    “…The resultant m(6)A “writers” allow functional comparison of single site methylation in different mRNA regions. …”
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    Programmable RNA N(6)-methyladenosine editing by CRISPR-Cas9 conjugates
  7. 1607
    “…N(6)-methyladenosine (m(6)A) is the most abundant eukaryote mRNA modification, modulated by regulators known as epigenetic writers, erasers and readers, which are known to serve crucial roles in mRNA metabolism. …”
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    Dysregulation of N(6)-methyladenosine regulators predicts poor patient survival in mantle cell lymphoma
  8. 1608
    “…All three families of epigenetic proteins—readers, writers, and erasers—are druggable targets that can be addressed through small-molecule inhibitors. …”
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    The timeline of epigenetic drug discovery: from reality to dreams
  9. 1609
    “…This variation in the RNA modification status can be the result of altered modifier expression (writers, readers or erasers), but also due to components of the machineries (C/D or H/ACA boxes) or alterations of proteins involved in modifier expression. …”
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    Disruption of the RNA modifications that target the ribosome translation machinery in human cancer
  10. 1610
    por Hammond, Philip
    Publicado 2020
    “…This article is a book review of Beyond Confrontation: Globalists, Nationalists and Their Discontents by Phil Mullan. Like other writers, Mullan warns of the danger of rising global tensions, but what marks out his contribution is a demystifying historical analysis which identifies the underlying sources of conflict and offers an optimistic and forward-looking vision. …”
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    Phil Mullan, Beyond Confrontation: Globalists, Nationalists and Their Discontents: Emerald Publishing, 2020, 256p, $27.99, ISBN: 978-1-83982-563-7 (paperback), ISBN: 978-1-83982-560-6 (online), ISBN: 978-1-83982-562-0 (epub)
  11. 1611
    “…Mutation or deletion of these epigenetic writers often renders cells unable to epigenetically “switch on” critical gene sets that are required to exit the GC reaction, differentiate, repair DNA, and other essential cellular functions. …”
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    Genetic and epigenetic determinants of diffuse large B-cell lymphoma
  12. 1612
    “…By combining pharmacological modulation of EMT, synthetic genetic tracing, and CRISPR interference screens, we uncovered a minority of kinases and several chromatin remodelers, writers, and readers governing homeostatic EMT in lung cancer cells. …”
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    Functional antagonism of chromatin modulators regulates epithelial-mesenchymal transition
  13. 1613
    “…Throughout the history of languages, poets and writers have used linguistic tools to enhance euphony in their creations. …”
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    Sooo Sweeet! Presence of Long Vowels in Brand Names Lead to Expectations of Sweetness
  14. 1614
    “…In this review, we first examine and summarize the molecular and cellular functions of m(6)A methylation and its readers, writers, and erasers in the cardiovascular system. …”
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    RNA Modification by m(6)A Methylation in Cardiovascular Disease
  15. 1615
    “…In the last few decades, growing numbers of RNA modifications have been identified not only in abundant ribosomal (rRNA) and transfer RNA (tRNA) but also in messenger RNA (mRNA). In addition, many writers, erasers and readers that dynamically regulate the chemical marks have also been characterized. …”
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    Regulatory roles of RNA modifications in breast cancer
  16. 1616
    “…N(6)-methyladenosine (m(6)A) is a prevalent internal modification in eukaryotic RNAs regulated by the so-called “writers”, “erasers”, and “readers”. m(6)A has been demonstrated to exert critical molecular functions in modulating RNA maturation, localization, translation and metabolism, thus playing an essential role in cellular, developmental, and disease processes. …”
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    Crosstalk between N6-methyladenosine modification and circular RNAs: current understanding and future directions
  17. 1617
    por Zhang, Nan, Zuo, Yuxin, Peng, Yu, Zuo, Lielian
    Publicado 2021
    “…These proteins are subdivided into writers (METTL3, METTL14, WTAP), erasers (ALKBH5, FTO), and readers (YTHDF1/2/3) according to their functions in m6A modification. …”
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    Function of N6-Methyladenosine Modification in Tumors
  18. 1618
    “…Deletion of the 5hmC writers Tet1, Tet2, and Tet3 from postmitotic PCs prevents loss of 5mC and 5hmC in regulatory domains and gene bodies, and hinders transcriptional and epigenetic developmental transitions. …”
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    5-Hydroxymethylcytosine-mediated active demethylation is required for mammalian neuronal differentiation and function
  19. 1619
    “…Here, we review the general role of m6A, highlighting recent advances related to the three major types enzymes that determine the level of m6A modification (i.e., writers, erasers, and readers) and the regulatory mechanism by which m6A influences multiple stages of RNA metabolism. …”
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    Dynamic regulation and functions of mRNA m6A modification
  20. 1620
    “…Here, we review the latest progresses in the biological roles of m(5)C modifications and how it is regulated by corresponding “writers”, “readers” and “erasers” proteins, as well as the potential molecular mechanism in tumorigenesis and cancer immunotherapy.…”
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    Biological roles of RNA m(5)C modification and its implications in Cancer immunotherapy
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