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1701“…METHODOLOGY: In order to accomplish this, survey research was the writers' favored technique. 279 respondents provided self-reporting information and supervisory assessments, from which we acquired data. …”
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1702“…In this review, we will focus on three epitranscriptomic marks, namely pseudouridine (Ψ), N(6)-methyladenosine (m(6)A) and 5-methylcytosine (m(5)C). We will introduce writers, readers, and erasers of these modifications, and we will present methods for their detection. …”
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1703“…All these modifications are highly interconnected, because the writers and erasers of one mark, DNA methyltransferases (DNMTs) and ten eleven translocation enzymes (TETs) in the case of DNA methylation, are directly or indirectly targeted and regulated by other marks. …”
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1704“…Inappropriate request for health care services which are considered to be unnecessary for the patients has long been addressed by several writers. The hypothesis supplier induced demand refers to the induced demand initiated by the supplier who acts in his own economic self-interest rather than patient best interest. …”
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1705“…N6-methyladenosine (m6A) is the most prevalent internal modification of RNAs in eukaryotes. m6A regulators include m6A writers, m6A demethylases, and m6A binding proteins. …”
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1706por Li, Yanyan, Wang, Junbin, Liu, Quan, Yang, Fengmei, Chen, Lixiong, Xu, Hongjie, Jin, Weihua, Liu, Yu, Zhang, Wei, Yang, Fei, He, Zhanlong, Zhao, Yuan“…Exploring the impact of diet on the early establishment of gut microbiota in non-human primates can provide relevant clinical models for healthy infant growth and development. At present, few writers have focused on the composition and changes of the intestinal microbes of infant rhesus macaques throughout their progression from birth to formula feeding after weaning. …”
Publicado 2023
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1707“…Recent studies have demonstrated that N6-methyladenosine (m6A), the most abundant, dynamic, and reversible epigenetic RNA modification in eukaryotes, is regulated by a series of enzymes, including methyltransferases (writers), demethylases (erasers), and m6A recognition proteins (readers). …”
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1708“…In addition, brains at the early postnatal stage demonstrated substantial changes in both RNA cytosine methylation and gene expression of RNA cytosine methylation readers, writers, and erasers. Furthermore, differentially methylated transcripts were significantly enriched for genes regulating synaptic plasticity. …”
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1709por Lui, Julian C., Wagner, Jacob, Zhou, Elaine, Dong, Lijin, Barnes, Kevin M., Jee, Youn Hee, Baron, Jeffrey“…Overgrowth syndromes can be caused by pathogenic genetic variants in epigenetic writers, such as DNA and histone methyltransferases. …”
Publicado 2023
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1710“…A team of trained plain language writers worked with clinicians and subject matter experts to draft content that was deemed readable, understandable, and actionable by formal measures and drafts were further refined with additional community feedback. …”
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1711“…To examine the peristaltic motion of a Newtonian fluid through an axisymmetric tube, many writers assume that viscosity is either a constant or a radius exponential function in Stokes’ equations. …”
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1712“…Researchers from several fields can collaborate on difficult tasks with the assistance of nonhuman writers, promoting interdisciplinary research. Sadly, there are a number of significant disadvantages associated with employing nonhuman authors, including the potential for algorithmic prejudice. …”
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1713por Sologuren, Enrique“…To know about the teachers’ and students’ views on the process of training professional writers in engineering, the rhetorical model was complemented with an ethnographic phase (in the terms proposed by Swales: corroboration process with a couple of members of the community) before and after collecting the textual corpus. …”
Publicado 2023
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1714“…A number of writers, primarily in the field of psychophysiology, have suggested that breast cancer may be related to a variety of untoward psychological states and that these may be related in turn to having experienced misfortune in the social milieu. …”
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1715“…As multiple marks contributing to one outcome are generally brought about by complexes containing multiple catalytic and binding domains, it appears regulation of chromatin involves a web of writers and readers of histone modifications, chromatin remodeling activities and DNA methylation. …”
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1716“…Toward the goal of gene-specific GEM by overwriting epigenetic marks (Epigenetic Editing, EGE), instructive epigenetic marks need to be identified and their writers/erasers should then be fused to gene-specific DNA binding domains. …”
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1717por Chen, Hui, Kazemier, Hinke G, de Groote, Marloes L., Ruiters, Marcel H. J., Xu, Guo-Liang, Rots, Marianne G.“…Furthermore, this Epigenetic Editing approach is a powerful tool to investigate functions of epigenetic writers and erasers and to elucidate consequences of epigenetic marks.…”
Publicado 2014
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1718por Cowley, Stephen J.“…On this bio-cognitive view, peer-review constrains knowledge-making by writers, editors, reviewers. Authors are prompted to recursively re-aggregate symbolizations to present what are deemed acceptable knowledge claims. …”
Publicado 2015
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1719“…The activity of the epigenetic writers DNA methyltransferases (Dnmts) after olfactory reward conditioning is important for both stimulus-specific long-term memory (LTM) formation and extinction. …”
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1720“…Here, we simulate the binding of two proteins to describe how the phosphorylation of a single residue modulates the entire process. 14-3-3 protein family is considered a master regulator of phosphorylated proteins and from a modern point-of-view, protein phosphorylation is a three component system, with writers (kinases), erasers (phosphatases) and readers. …”
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