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Psicoterapia centrada en el cliente
6
Orientación psicológica
2
Psicoterapia
2
Estudio y enseñanza
1
Flute and piano music, Arranged
1
Folk songs, Spanish
1
Grabados
1
Historia natural
1
Instrumental settings
1
Matroides
1
Psicología humanista
1
Psicoterapeutas
1
Psicoterapia familiar
1
Scores and parts
1
Tierra
1
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1“…The title compound [systematic name: 3-(3,4-dihydroxyphenyl)-5-hydroxy-7-methoxy-4H-chromen-4-one monohydrate], C(16)H(12)O(6)·H(2)O, is a monohydrate of a natural product santal isolated from Wyethia mollis. In the santal molecule, the dihedral angle between the benzoquinone and dihydroxyphenyl fragments is 53.9 (1)° and an intramolecular O—H⋯O hydrogen bond occurs. …”
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2por Weber, Helga, Leal, Pamela, Stein, Stefan, Kunkel, Hana, García, Patricia, Bizama, Carolina, Espinoza, Jaime A., Riquelme, Ismael, Nervi, Bruno, Araya, Juan C., Grez, Manuel, Roa, Juan C.“…We evaluated the in vitro and in vivo antitumor efficacy of mTOR inhibitors, rapamycin and WYE-354. In vitro assays showed WYE-354 significantly reduced cell viability, migration and invasion and phospho-P70S6K expression in GBC cells. …”
Publicado 2015
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3“…We set out to evaluate the novel compound, [(125)I]WYE-230949, as a potential radionuclide imaging agent for the histamine H(3) receptor in brain. [(125)I]WYE-230949 had a high in vitro affinity for the rat histamine H(3) receptor (K(d) of 6.9 nM). …”
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4por Ibrahim, Sara M., Bakhashab, Sherin, Ilyas, Asad M., Pushparaj, Peter N., Karim, Sajjad, Khan, Jalaluddin A., Abuzenadah, Adel M., Chaudhary, Adeel G., Al-Qahtani, Muhammed H., Ahmed, Farid“…Furthermore, WYE-354 stimulated the ATPase activity of ABCB1, which was consistent with in silico predictions using a human ABCB1 mouse homology model, indicating that WYE-354 is a potent substrate of ABCB1. …”
Publicado 2019
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7por Wang, Jingqiu, Yang, Dong-Hua, Yang, Yuqi, Wang, Jing-Quan, Cai, Chao-Yun, Lei, Zi-Ning, Teng, Qiu-Xu, Wu, Zhuo-Xun, Zhao, Linguo, Chen, Zhe-Sheng“…We demonstrated that WYE-354 is a substrate of ABCB1, that the overexpression of the ABCB1 transporter decreases the efficacy of WYE-354, and that the resistant WYE-354 can be reversed by an ABCB1 inhibitor at a pharmacological achievable concentration. …”
Publicado 2020
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9por Pan, Xiao-dong, Gu, Dong-hua, Mao, Jia-Hui, Zhu, Hua, Chen, Xinfeng, Zheng, Bing, Shan, Yuxi“…We here tested the potential anti-RCC activity by a novel mTOR kinase inhibitor WYE-687in vitro and in vivo.WYE-687 was cytotoxic and anti-proliferative to established RCC cell lines (786-O and A498) and primary human RCC cells. …”
Publicado 2017
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