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Mostrando 921 - 940 Resultados de 1,767 Para Buscar '"Xenopus laevis"', tiempo de consulta: 2.62s Limitar resultados
  1. 921
    “…The interaction network obtained from the data was validated globally in 4 distant species (Xenopus laevis, Nematostella vectensis, Dictyostelium discoideum, Saccharomyces cerevisiae) and locally by targeted affinity-purification experiments. …”
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    Proteome-wide dataset supporting the study of ancient metazoan macromolecular complexes
  2. 922
    “…In this study we demonstrate that expressing the gene for either Arabidopsis thaliana inositol transporter AtINT2 or AtINT4 in Saccharomyces cerevisiae leads to increased arsenic accumulation and elevated sensitivity to arsenite [As(III)], and Xenopus laevis oocytes expressing AtINT2 import As(III). …”
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    Inositol transporters AtINT2 and AtINT4 regulate arsenic accumulation in Arabidopsis seeds
  3. 923
    “…Receptors were expressed heterologously in Xenopus laevis oocytes, and whole-cell electrophysiology was used to monitor channel activity. …”
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    Perturbation of Critical Prolines in Gloeobacter violaceus Ligand-gated Ion Channel (GLIC) Supports Conserved Gating Motions among Cys-loop Receptors
  4. 924
    “…However, the molecular mechanism has not yet been determined. By using Xenopus laevis egg extract, we found that SUMOylation of DNA topoisomerase IIα (TOP2A) CTD regulates the localization of the histone H3 kinase Haspin and phosphorylation of histone H3 at threonine 3 at the centromere, two steps known to be involved in the recruitment of the chromosomal passenger complex (CPC) to kinetochores in mitosis. …”
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    SUMOylation of DNA topoisomerase IIα regulates histone H3 kinase Haspin and H3 phosphorylation in mitosis
  5. 925
    “…In all vertebrates, nodal family members have specific waves of expression required for tissue specification and axis formation. In Xenopus laevis, six nodal genes are expressed before gastrulation, raising the question of whether they have specific roles or act redundantly with each other. …”
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    Nodal signalling in Xenopus: the role of Xnr5 in left/right asymmetry and heart development
  6. 926
    por Riddiford, Nick, Schlosser, Gerhard
    Publicado 2016
    “…Using RNA-Seq in Xenopus laevis we screened for presumptive direct placodal target genes of Six1 and Eya1 by overexpressing hormone-inducible constructs of Six1 and Eya1 in pre-placodal explants, and blocking protein synthesis before hormone-inducing nuclear translocation of Six1 or Eya1. …”
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    Dissecting the pre-placodal transcriptome to reveal presumptive direct targets of Six1 and Eya1 in cranial placodes
  7. 927
    “…To test whether the sequential activation of these microtubule assembly pathways, defined by centrosome maturation and nuclear envelope breakdown, plays any role in spindle assembly, we combined experiments in tissue culture cells and Xenopus laevis egg extracts with a mathematical model. …”
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    The sequential activation of the mitotic microtubule assembly pathways favors bipolar spindle formation
  8. 928
    “…Here we develop automated spindle-tracking software and apply it to characterize mitotic spindle dynamics in the Xenopus laevis embryonic epithelium. We find that metaphase spindles first undergo a sustained rotation that brings them on-axis with their final orientation. …”
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    Automated mitotic spindle tracking suggests a link between spindle dynamics, spindle orientation, and anaphase onset in epithelial cells
  9. 929
    “…Methods: We expressed recombinant NMDARs with and without the GluN2A (R586K) variant in Xenopus laevis oocytes and in primary cultured mouse neurons, and made electrophysiological recordings assessing Mg (2+) block, single-channel conductance, mean open time and current density. …”
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    Functional assessment of the NMDA receptor variant GluN2A (R586K)
  10. 930
    “…We investigated the hydrodynamic behavior of the CPC in Xenopus laevis egg cytosol using sucrose gradient sedimentation and in HeLa cells using fluorescence correlation spectroscopy. …”
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    Chromosomal passenger complex hydrodynamics suggests chaperoning of the inactive state by nucleoplasmin/nucleophosmin
  11. 931
    “…Early studies in Xenopus laevis have shown that intestinal remodeling involves complete degeneration of the larval epithelium and de novo formation of adult stem cells through dedifferentiation of some larval epithelial cells. …”
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    Direct Regulation of Histidine Ammonia-Lyase 2 Gene by Thyroid Hormone in the Developing Adult Intestinal Stem Cells
  12. 932
    “…Here, we reveal assembly rules of native GABA(A)R complexes that explain GABA(A)R subunit subcellular distributions using mice and Xenopus laevis oocytes. First, α subunits possess intrinsic signals to segregate into distinct pentamers. …”
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    Assembly rules for GABA(A) receptor complexes in the brain
  13. 933
    “…To understand the molecular mechanisms underlying this process, we isolated Xenopus laevis Brca2. We demonstrated that Brca2 protein prevents single-stranded DNA gap accumulation at replication fork junctions and behind them by promoting Rad51 binding to replicating DNA. …”
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    Smarcal1-Mediated Fork Reversal Triggers Mre11-Dependent Degradation of Nascent DNA in the Absence of Brca2 and Stable Rad51 Nucleofilaments
  14. 934
    “…Xenbase (www.xenbase.org) is an online resource for researchers utilizing Xenopus laevis and Xenopus tropicalis, and for biomedical scientists seeking access to data generated with these model systems. …”
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    Xenbase: a genomic, epigenomic and transcriptomic model organism database
  15. 935
    “…Inhibition of SNAT2 and LAT1 was confirmed by recombinant expression in Xenopus laevis oocytes. The reported reduction of tumor growth in pre-clinical models may be explained by a significant disruption of AA homeostasis.…”
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    Disruption of Amino Acid Homeostasis by Novel ASCT2 Inhibitors Involves Multiple Targets
  16. 936
    “…Analogously, we tested the use of melanophore cells from Xenopus laevis, containing compartments (melanosomes) filled with strongly absorbing melanin, as whole-cell sensors for optoacoustic imaging. …”
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    Whole-Cell Photoacoustic Sensor Based on Pigment Relocalization
  17. 937
    “…The use of Xenopus laevis as a model for vertebrate developmental biology is limited by a lack of antibodies specific for embryonic antigens. …”
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    Isolation of nanobodies against Xenopus embryonic antigens using immune and non-immune phage display libraries
  18. 938
    “…Here, we determined the channel activities of CNGC11 and CNGC12 utilizing the two-electrode voltage-clamp technique in the Xenopus laevis oocyte heterologous expression system. …”
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    Electrophysiological Studies Revealed CaM1-Mediated Regulation of the Arabidopsis Calcium Channel CNGC12
  19. 939
    “…Initially, the hasB (UDP-Glucose dehydrogenase) gene from Xenopus laevis (xlhasB) is inserted. After that, four strains are constructed harboring different hasA (HA Synthase) genes, three of humans (hshasA1, hshasA2, and hshasA3) and one with the bacteria Pasteurella multocida (pmhasA). …”
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    Heterologous Hyaluronic Acid Production in Kluyveromyces lactis
  20. 940
    “…In vitro-generated transcripts of both genes as well as the S. cerevisiae HXT7 high-affinity glucose transporter were injected into Xenopus laevis oocytes and subsequent glucose uptake rates were assayed using (14)C-labelled glucose. …”
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    Identification and characterisation of two high-affinity glucose transporters from the spoilage yeast Brettanomyces bruxellensis
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