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  1. 1581
    “…We then used a conditional demyelination Xenopus laevis model to assess the dose-response of siponimod on remyelination. …”
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    Increased Remyelination and Proregenerative Microglia Under Siponimod Therapy in Mechanistic Models
  2. 1582
    “…PURPOSE: Müller glia (MG) in the retina of Xenopus laevis (African clawed frog) reprogram to a transiently amplifying retinal progenitor state after an injury. …”
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    Derivation and Characterization of Murine and Amphibian Müller Glia Cell Lines
  3. 1583
    “…This study established proof-of-principle using giant, ∼250-µm-diameter cells from embryos of the frog Xenopus laevis and small, ∼35-µm-diameter neurons in culture from the mouse hippocampus. …”
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    Capillary Electrophoresis Mass Spectrometry for Scalable Single-Cell Proteomics
  4. 1584
    “…Here, we explored the effect of human TMPRSS2 on human αβγ-ENaC heterologously expressed in Xenopus laevis oocytes. We found that coexpression of TMPRSS2 stimulated ENaC-mediated whole-cell currents by approximately threefold, likely because of an increase in average channel open probability. …”
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    Transmembrane serine protease 2 (TMPRSS2) proteolytically activates the epithelial sodium channel (ENaC) by cleaving the channel’s γ-subunit
  5. 1585
    “…For each nematode species, we investigated the ability of these subunits to form either homomeric or heteromeric GluCls when expressed in Xenopus laevis oocytes and carried out detailed pharmacological characterization of the functional channels. …”
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    Pharmacological characterization of novel heteromeric GluCl subtypes from Caenorhabditis elegans and parasitic nematodes
  6. 1586
    “…EXPERIMENTAL APPROACH: Functional studies of effects by seven antipsychotic and antidepressant medications were performed in several GABA(A) receptor subtypes by two‐electrode voltage‐clamp electrophysiology using Xenopus laevis oocytes. Computational structural analysis was employed to design mutated constructs of the α5 subunit, probing a novel binding site. …”
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    Tricyclic antipsychotics and antidepressants can inhibit α5‐containing GABA(A) receptors by two distinct mechanisms
  7. 1587
    “…Ectopic expression in Xenopus laevis oocytes revealed that they mediate low-affinity nitrate transport. …”
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    Vacuolar nitrate efflux requires multiple functional redundant nitrate transporter in Arabidopsis thaliana
  8. 1588
    “…To elucidate this channel’s pharmacological properties, we used Xenopus laevis oocytes for expression and performed two-electrode voltage-clamp electrophysiology. …”
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    Nodulisporic acid produces direct activation and positive allosteric modulation of AVR-14B, a glutamate-gated chloride channel from adult Brugia malayi
  9. 1589
    “…Here, we tested the hypothesis that leptin promotes both the quality and speed of wound healing in the South African clawed frog, Xenopus laevis. First, fluorescent immunohistochemistry using a polyclonal antibody specific to Xenopus leptin showed that in juvenile dorsal skin, leptin protein is expressed in the dorsal epidermal layer, as well in blood vessel endothelial cells and sensory nerves that run along the base of the dermis. …”
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    Evolutionary conservation of leptin effects on wound healing in vertebrates: Implications for veterinary medicine
  10. 1590
    por Hone, Arik J., McIntosh, J. Michael
    Publicado 2022
    “…Here we assessed whether cholinergic ligands can enable or uncover ionic functions from homomeric α10 nAChRs. Xenopus laevis oocytes expressing human α10 subunits were exposed to a panel of ligands and examined for receptor activation using voltage-clamp electrophysiology. …”
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    Alkaloid ligands enable function of homomeric human α10 nicotinic acetylcholine receptors
  11. 1591
    “…Here, we combine different experimental models, cell-based approaches, neuronal culture assays, and rodent behavior tests with Xenopus laevis phenotypic analysis to characterize quercitrin, a natural compound, as a novel Wnt signaling potentiator. …”
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    The Flavonol Quercitrin Hinders GSK3 Activity and Potentiates the Wnt/β-Catenin Signaling Pathway
  12. 1592
    “…In this paper we investigated the mechanism of action of Maganin-2 (Mag-2), a well-known antimicrobial peptide isolated from the African clawed frog Xenopus laevis, by functional proteomic approaches. Several proteins belonging to E. coli macromolecular membrane complexes were identified as Mag-2 putative interactors. …”
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    The antimicrobial peptide Magainin-2 interacts with BamA impairing folding of E. coli membrane proteins
  13. 1593
    por Noonan, Jennifer D., Beech, Robin N.
    Publicado 2022
    “…Neurotransmission is an important target for anthelmintic drugs, where receptor characteristics and response can be examined through reconstitution ex vivo in Xenopus laevis oocytes. The homomeric ACR-16 nicotine sensitive acetylcholine receptors (N-AChRs) of several helminth species have been characterized in this way. …”
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    Reconstitution of an N-AChR from Brugia malayi, an evolved change in acetylcholine receptor accessory protein requirements in filarial parasites
  14. 1594
    “…Finally, we present the results of an experimental test of one of the model's predictions in early Xenopus laevis embryos: thioridazine (a dopamine antagonist that may reduce sensory precision in biological systems) induced developmental (anatomical) defects as predicted. …”
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    Active inference, morphogenesis, and computational psychiatry
  15. 1595
    “…Geometry and exchange coupling (singlet–triplet energy gap: 2J) of photoinduced secondary CS states composed of flavin adenine dinucleotide radical anion (FAD(−•)) and radical cation W(B)(H)(+•) in the cryptochrome DASH from Xenopus laevis were clarified by time-resolved electron paramagnetic resonance. …”
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    Orientations and water dynamics of photoinduced secondary charge-separated states for magnetoreception by cryptochrome
  16. 1596
    “…In the present study, we tested an 8‐day assay to evaluate the toxicity of two organophosphates, diazinon and chlorpyrifos, on Xenopus laevis, that is, on biochemical, morphological, and life‐history traits related to locomotion capacities. …”
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    The Amphibian Short‐Term Assay: Evaluation of a New Ecotoxicological Method for Amphibians Using Two Organophosphate Pesticides Commonly Found in Nature—Assessment of Biochemical, Morphological, and Life‐History Traits
  17. 1597
    “…The Zn-finger was first reported as a repeated Zn-binding motif, comprising conserved cysteine (Cys) and histidine (His) ligands, in Xenopus laevis oocytes as a transcription factor (TF) IIIA (or TFIIIA). …”
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    The intertwining of Zn-finger motifs and abiotic stress tolerance in plants: Current status and future prospects
  18. 1598
    “…Changing skin colour/reflectance and locomotor activity are both well-recognized temperature regulatory mechanisms, but little is known of the participating thermosensor/s. We find that Xenopus laevis tadpoles put in the cold exhibit a temperature-dependent, systemic, and rapid melanosome aggregation in melanophores, which lightens the skin. …”
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    TRPM8 thermosensation in poikilotherms mediates both skin colour and locomotor performance responses to cold temperature
  19. 1599
    “…Two odorant receptors (BdorOR7a-6 and BdorOR13a) are identified as key receptors for 1-octen-3-ol perception by qPCR analysis, heterologous expression in Xenopus laevis oocytes and HEK 293 cells followed by in vitro binding assays, as well as CRISPR/Cas9 genome editing in B. dorsalis. …”
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    Two odorant receptors regulate 1-octen-3-ol induced oviposition behavior in the oriental fruit fly
  20. 1600
    “…Biophysical analysis of the wheat Lr67sus and Lr67res protein variants was performed using Xenopus laevis oocytes as a heterologous expression system. …”
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    Expression of the wheat multipathogen resistance hexose transporter Lr67res is associated with anion fluxes
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