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  1. 1741
    “…Pathogenicity of all previously unreported missense variants was further supported by electrophysiological studies in Xenopus laevis oocytes. We compare CLCN4-related disorder with conditions related to dysfunction of other members of the CLC family.…”
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    De novo and inherited mutations in the X-linked gene CLCN4 are associated with syndromic intellectual disability and behavior and seizure disorders in males and females
  2. 1742
    “…Human AQP1 wild type, AQP1 mutant channels with alanines substituted for two arginines (R159A+R160A), and mutants with proline substituted for single residues threonine (T157P), aspartate (D158P), arginine (R159P, R160P), or glycine (G165P) were expressed in Xenopus laevis oocytes. Conductance responses were analyzed by two-electrode voltage clamp. …”
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    Identification of Loop D Domain Amino Acids in the Human Aquaporin-1 Channel Involved in Activation of the Ionic Conductance and Inhibition by AqB011
  3. 1743
    “…Using two-electrode voltage clamp on Xenopus laevis oocytes injected with GsCLC-c2 cRNA, we found that GsCLC-c2 transports both Cl(−) and NO(3)(−) with slightly different affinity, and the affinity toward Cl(−) was pH-independent. …”
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    Identification and functional characterization of the chloride channel gene, GsCLC-c2 from wild soybean
  4. 1744
    “…Direct experimental data on the interaction with defined receptor subtypes were obtained by heterologous expression of various human nAChR subtypes in Xenopus laevis oocytes and measurement of the transmembrane currents evoked by exposure to putative ligands. …”
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    Acute effects of the imidacloprid metabolite desnitro-imidacloprid on human nACh receptors relevant for neuronal signaling
  5. 1745
    “…Co- immunoprecipitation (Co-IP)/Mass Spectrometry (MS) analysis identified SmRho1 partner proteins and we used two heterologous expression systems (Y2H assay and Xenopus laevis oocytes) to study interactions between SmHDAC8 and SmRho1 isoforms. …”
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    Histone deacetylase 8 interacts with the GTPase SmRho1 in Schistosoma mansoni
  6. 1746
    por Lukas, Paul, Ziermann, Janine M.
    Publicado 2022
    “…The comparison of its chondrocranium (cartilaginous neuro- & viscerocranium) development with other basal anurans (Xenopus laevis, Bombina orientalis) will help establishing the ancestral pattern of chondrification sequences in anurans and will serve as basis for further studies to reconstruct ancestral conditions in amphibians, tetrapods, and vertebrates. …”
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    Sequence of chondrocranial development in basal anurans—Let’s make a cranium
  7. 1747
    “…The function of the two transporters was investigated by heterologous expression in Xenopus laevis oocytes and two‐electrode voltage‐clamp recordings of transport and presteady‐state currents. …”
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    Functional characterization of Atlantic salmon (Salmo salar L.) PepT2 transporters
  8. 1748
    “…Phylogenetic and tissue expression analyses allowed for the identification of SseEF1A1 and SseEF1A2 as the Senegalese sole counterparts of mammalian eEF1A1 and eEF1A2, respectively, and of Sse42Sp50 as the ortholog of Xenopus laevis and teleost 42Sp50 gene. The other two elongation factors, SseEF1A3 and SseEF1A4, represent novel genes that are mainly expressed in gills and skin. …”
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    Molecular characterization and expression analysis of five different elongation factor 1 alpha genes in the flatfish Senegalese sole (Solea senegalensis Kaup): Differential gene expression and thyroid hormones dependence during metamorphosis
  9. 1749
    “…The following double and triple mutants of GLRA1 cDNA (encoding human glycine receptor alpha 1 subunit) were injected into Xenopus laevis oocytes: I229C/A288C, I229C/A288C/C290S, A288C/Y406C, A288C/W407C, A288C/I409C, and A288C/Y410C along with the corresponding single mutants and wild-type GLRA1. …”
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    Inter- and Intra-Subunit Butanol/Isoflurane Sites of Action in the Human Glycine Receptor
  10. 1750
    “…The capacity of LRRK2 to regulate WNT/PCP signaling in vivo was tested in Xenopus laevis’ early development. RESULTS: Our proteomic analysis identified that LRRK2 interacts with proteins involved in WNT/PCP signaling such as the PDZ domain-containing protein GIPC1 and Integrin-linked kinase (ILK) in dopaminergic cells in vitro and in the mouse ventral midbrain in vivo. …”
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    A proteomic analysis of LRRK2 binding partners reveals interactions with multiple signaling components of the WNT/PCP pathway
  11. 1751
    “…To resolve this issue, we coexpressed P2X4 and P2X7 receptor subunits labeled with green (EGFP) and red (TagRFP) fluorescent proteins in Xenopus laevis oocytes and investigated a putative physical interaction between the fusion proteins by Förster resonance energy transfer (FRET). …”
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    Interaction of Purinergic P2X4 and P2X7 Receptor Subunits
  12. 1752
    por Özugur, Suzan, Kunz, Lars, Straka, Hans
    Publicado 2020
    “…RESULTS: We used isolated preparations of Xenopus laevis tadpoles to perform a quantitative analysis of O(2) levels in the brain under in vivo-like conditions. …”
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    Relationship between oxygen consumption and neuronal activity in a defined neural circuit
  13. 1753
    “…Heterozygous and homozygous Kv3.3 A671V and Kv4.3 V374A variants were evaluated in Xenopus laevis oocytes using 2-electrode voltage-clamp. …”
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    V374A KCND3 Pathogenic Variant Associated With Paroxysmal Ataxia Exacerbations
  14. 1754
    “…Electrophysiology experiments with Xenopus laevis oocytes and heterologous expression in yeast revealed that Trire2_104072 is a high-affinity l-arabinose symporter with a K(m) value in the range of [Formula: see text]  0.1–0.2 mM. …”
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    Functional characterization of a highly specific l-arabinose transporter from Trichoderma reesei
  15. 1755
    “…METHODS: Using a combination of whole-brain clearing and immunohistochemistry staining techniques we characterized DSCAM expression and the projection of ventral and dorsal retinal fibers starting from the eye, following to the optic nerve and chiasm, and into the terminal target in the optic tectum in Xenopus laevis tadpoles. We then assessed the effects of DSCAM on the establishment of retinotopic maps through spatially and temporally targeted DSCAM knockdown on retinal ganglion cells (RGCs) with axons innervating the optic tectum. …”
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    DSCAM is differentially patterned along the optic axon pathway in the developing Xenopus visual system and guides axon termination at the target
  16. 1756
    “…Wild-type and mutant c-Myc-tagged human NaPi-IIb constructs were expressed in Xenopus laevis oocytes. The transport function was investigated with a (32)Pi uptake assay. …”
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    Impaired phosphate transport in SLC34A2 variants in patients with pulmonary alveolar microlithiasis
  17. 1757
    “…Knockdown of target protein levels in Xenopus laevis oocytes indicated that the PABP4, CELF2, LSM14A/B, ELAVL1, ELAVL2, ELAVL4, and PUM1 proteins are required for Musashi target mRNA translational activation. …”
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    OR08-2 Functional Association of the Stem Cell Protein Musashi With LSM14B in Control of mRNA Translation
  18. 1758
    “…Subsequently, the open-reading frames (ORFs) encoding for mHv1 isoforms were cloned and expressed in Xenopus laevis oocytes for proton current recording using a macro-patch voltage clamp. …”
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    N-terminal region is responsible for mHv1 channel activity in MDSCs
  19. 1759
    “…Further experiments on neuronal α3β2, α4β2, and α9α10 nAChRs, expressed in Xenopus laevis oocytes, showed that similar potencies for BBIQAs1, 2, and d-TC. …”
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    Curare alkaloids from Matis Dart Poison: Comparison with d-tubocurarine in interactions with nicotinic, 5-HT(3) serotonin and GABA(A) receptors
  20. 1760
    “…As assessed by expression in Xenopus laevis oocytes and two-electrode voltage clamp measurements, zebrafish PepT1a, as PepT1b, is electrogenic, Na(+)-independent, and pH-dependent and functions as a low-affinity system, with K(0.5) values for Gly-Gln at − 60 mV of 6.92 mmol/L at pH 7.6 and 0.24 mmol/L at pH 6.5 and at − 120 mV of 3.61 mmol/L at pH 7.6 and 0.45 mmol/L at pH 6.5. …”
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    The peptide transporter 1a of the zebrafish Danio rerio, an emerging model in nutrigenomics and nutrition research: molecular characterization, functional properties, and expression analysis
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