“…We calculated incidence of first HZ episode by dividing the number of cases by the total number of person-years (p-y). A case was a censoring event. We used Poisson regression to compare HZ incidence by race before and after 2007. …”
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“…The 10-y ASCVD risk was estimated using the Pooled Cohort Equations (PCE) for 2976 subjects, aged 40–70 y; a risk score ≥7.5% was defined as ‘elevated’ ASCVD risk. …”
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“…Eligibility criteria were reporting empirical data from at least 2 full-mouth dental caries examinations in a closed cohort during a follow-up of at least 3 y, a first examination after 1974, a second examination before the age of 22 y, caries assessed as dentine caries (d(3)/D(3)), and caries reported in dmfs/DMFS (decayed, missing, and filled surfaces), dmft/DMFT (decayed, missing, and filled teeth), or caries-free participants. …”
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“…METHOD: Fifteen in-depth interviews were conducted with private obstetricians and hospital administrators from eight districts of Madhya Pradesh who had participated in the JShY. A Framework approach was used to analyze the data. …”
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“…In the present study, we conjugated (90)Y, a high-energy beta-particle-emitting radionuclide, to our αGPC3 antibody to develop a novel antibody-directed radiotherapeutic approach for HCC. …”
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“…Ya se trate de una localización ocular de algunas enfermedades dermatológicas, como las dermatosis infecciosas, o de auténticos síndromes oculocutáneos, la exploración clínica especializada, y a veces repetida, suele orientar el tratamiento. …”
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“…The HRQoL was measured by the EQ-5D-Y, a five-dimensional descriptive system for children and youth. …”
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“…RESULTS: All isolates analysed for k13 propeller allele were observed as wild-type in samples collected post implementation of ACT in Pakistan. C580Y, A675V, Y493H and R539T variants associated with reduced susceptibility to artemisinin-based combination therapy (ACT) were not found. …”
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“…Using sagittal magnetic resonance imaging scans of the knee, points on the articular cartilage of the posterolateral tibial plateau were selected and curve-fitted to a power function (y = a × x(n)). For coefficient a and coefficient n, both variables modulated the shape of the curve, where a larger magnitude represented an increase in slope steepness. …”
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“…Here we propose a rapid and accessible protocol based on Sanger sequencing of a single PCR fragment that is able to identify and discriminate all SARS-CoV-2 variants of concern (VOCs) identified so far, according to each characteristic mutational profile at the Spike-RBD region (K417N/T, E484K, N501Y, A570D). Twelve COVID-19 samples from Brazilian patients were evaluated for both WGS and Sanger sequencing: three P.2, two P.1, six B.1.1 and one B.1.1.117 lineage. …”
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“…RESULTS: We identified that SARS-CoV-2 genomes from four patients diagnosed in our institute harboured a new set of amino acid substitutions including L18F, L452R, N501Y, A653V, H655Y, D796Y, G1219V ± Q677H. These spike N501Y genomes are the first of Nextstrain clade 19B. …”
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“…Based on the partial sequencing of SGTF samples 93.5% (n = 29/31) showed the characteristic N501Y, A570D, P681H, and T716I mutations found in the B.1.1.7 variant. …”
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“…RESULTS: The patients had a median age of 1.80 years at diagnosis (range, 1.4 m–13.42 years), and were followed up for 9.17 months in median (range, 4 d–11.14 y). A total of 16 patients achieved complete remission (CR), and 7 survived without reoccurrence till December 2019. …”
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“…In the mutational analysis, we found 639 mutations in the spike protein sequence of SARS-CoV-2 and identified/highlighted 20 common mutations L5F, T22I, T29I, H49Y, L54F, V90F, S98F, S221L, S254F, V367F, A520S, T572I, D614G, H655Y, P809S, A879S, D936Y, A1020S, A1078S, and H1101Y. Further, we have analyzed the crystal structure of the 2019-nCoV chimeric receptor-binding complex with ACE2 (PDB ID: 6VW1) as a major target protein. …”
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“…Response surface regression indicated linear effects on albumen and yolk percentages (P < 0.01) increasing and decreasing, respectively, as AA levels augmented; consequently, AA had a negative linear effect on Y:A ratio (P = 0.004) with quadratic effects (P < 0.01) of age (R(2) = 0.92). …”
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“…Two signature spike mutations of concern are E484K, which has a crucial role in the loss of neutralizing activity of antibodies, and N501Y, a driver of rapid worldwide transmission of the B.1.1.7 lineage. …”
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“…Los objetivos secundarios fueron: mejora de los parámetros respiratorios, reducción de las complicaciones, de la duración de la ventilación mecánica, de la estancia en unidad de cuidados intensivos y hospitalaria, así como de la mortalidad en unidad de cuidados intensivos, hospitalaria y a los 90 días. También se analizaron los factores relacionados con la reintubación. …”
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“…Combining this new assembly with pool-sequencing of male and female genomes, we identified id2bbY, a duplicated copy of the inhibitor of DNA binding 2b (id2b) gene on the Y chromosome as candidate male sex-determining gene. …”
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“…We show how the computer simulation and the successful solution of the crisis serves as a vehicle for a broader discussion about what kind of future we want, a future where the conquest of space offers new opportunities, e.g. for solving the environmental crisis. While normally in Y/A speculative fiction, technology is almost exclusively depicted as ostensibly serving human needs, in Pandemic it is thanks to technology, and the younger generation’s particular skills, that the disease is conquered. …”
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“…INTRODUCTION: Il n’y a aucune preuve sur le rôle de la prise antérieure des corticostéroïdes inhalés (CSI) dans l’évolution de la COVID-19. …”
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