“…We focused our work on AppY, a transcriptional regulator encoded on the DLP12 prophage. …”
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“…Using whole‐genome sequencing of wild‐caught samples and a lab cross, we identify AmhY, a male specific duplication of the gene Amh, as the candidate master sex determination gene. …”
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“…We report here that the sequence of the transcript is tandemly repeated on nine chromosomes (1, 2, 7, 9, 10, 16, 17, 22, and Y). A detailed analysis of its genomic localization and annotation in the T2T-CHM13 assembly revealed that the sequence belonged to HSAT2 (HS2) but not to the HS3 family of tandemly repeated DNA. …”
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“…Genome-based traits were categorized into the Y-A-S trait-based framework for high growth yield, resource acquisition, and stress tolerance. …”
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“…CONTENIDO: La cuantificación en sangre de hormona paratiroidea (PTH) presenta una importante variabilidad analítica debido a la heterogeneidad de sus formas circulantes y a la configuración antigénica de los diferentes métodos disponibles. …”
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“…In 90th of XX Russian psychiatrist Y. A. Alexandrovsky expressed opinion of presence the group of so-called social-stress disorders (SSD) that was determined like psychogenic-actual for most people in definite social, economic and political situation. …”
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“…This result in addition to arid conditions in Patagonia prevailing since 16 m.y.a made us think that Patagonian beetle pond-dwellers are basally adapted to aridity. …”
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“…Indeed, both BDNF signaling and the adenosinergic system are altered in Mecp2-null mice (Mecp2(−/y)), a representative model of severe manifestation of RTT. …”
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“…To assess the effect of α-TM and TD on the percentage of cellular viability in Olfactory Ensheathing Cells (OECs), a peculiar glial cell type of the olfactory system used as normal cells, and in SH-SY5Y, a neuroblastoma cancer cell line, an MTT test was performed. …”
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“…A., Sánchez, D. P., Negulyaev, Y. A., Patel, R. H., Anand, P., Korchev, Y. E., Bennett, D. …”
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“…Moreover, ASIP-treated cells showed reduced proliferation and a melanoblast-like appearance, seen also in melanocyte lines from yellow (A(y)/a and Mc1r(e)/ Mc1r(e)) mice. However ASIP-YY, a C-terminal fragment of ASIP, induced neither biological nor pigmentary changes. …”
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“…Introduction of this Arg at the equivalent position of SacY (A26) increased the RNA binding in vitro but also resulted in a relaxed specificity. …”
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“…The most studied comparison of aging and maximum lifespan potential (MLSP) among endotherms involves the 7-fold longevity difference between rats (MLSP 5y) and pigeons (MLSP 35y). A widely accepted theory explaining MLSP differences between species is the oxidative stress theory, which purports that reactive oxygen species (ROS) produced during mitochondrial respiration damage bio-molecules and eventually lead to the breakdown of regulatory systems and consequent death. …”
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“…Excessive drug taking also engages the activation of CRF in the medial prefrontal cortex, paralleled by deficits in executive function that may facilitate the transition to compulsive-like responding. Neuropeptide Y, a powerful anti-stress neurotransmitter, has a profile of action on compulsive-like responding for ethanol similar to a CRF(1) antagonist. …”
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“…The present study measured NO production in a human neuroblastoma (SH-SY5Y), a murine glial (BV2), a human endothelial cell line (HUVEC), and in primary cultures of human cerebral myocytes (HC-VSMCs) after experimental ischemia in vitro. …”
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“…In medaka, the master male sex-determining gene is dmrt1bY, a highly conserved downstream regulator of sex determination in vertebrates. …”
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“…The target population was females aged 14–23 y and the time horizon was 100 y. A total of eight different scenarios compared vaccination impact in terms of reduction in HPV-16/18-associated carcinomas (cervical, vulvar, vaginal, anal, penile and head and neck), HPV-6/11-related genital warts and recurrent respiratory papillomatosis, and incremental reduction in cervical cancer due to potential cross-protection. …”
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“…To overcome this problem, we developed an scFv secretion system in which scFv was fused with osmotically inducible protein Y (osmY), a bacterial secretory carrier protein, for efficient protein secretion. …”
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“…Nous rapportant le cas d'une patiente de 49 ans, notion de pose de stérilet il y a 20 ans, suivie en oncologie pour un carcinome canalaire infiltrant du sein ayant bénéficiée d'un patey puis chimiothérapie adjuvante actuellement sous hormonothérapie, qui dans le cadre du bilan d'extension, un scanner thoraco-abdomino-pelvienne a objectivé la présence d'un DIU en sous hépatique. …”
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