Identification of Key Small Non‐Coding MicroRNAs Controlling Pacemaker Mechanisms in the Human Sinus Node

por Petkova, Maria, Atkinson, Andrew J., Yanni, Joseph, Stuart, Luke, Aminu, Abimbola J., Ivanova, Alexandra D., Pustovit, Ksenia B., Geragthy, Connor, Feather, Amy, Li, Ning, Zhang, Yu, Oceandy, Delvac, Perde, Filip, Molenaar, Peter, D’Souza, Alicia, Fedorov, Vadim V., Dobrzynski, Halina
Publicado 2020

Reactivation of tumour suppressor in breast cancer by enhancer switching through NamiRNA network

por Liang, Ying, Lu, Qi, Li, Wei, Zhang, Dapeng, Zhang, Fanglin, Zou, Qingping, Chen, Lu, Tong, Ying, Liu, Mengxing, Wang, Shaoxuan, Li, Wenxuan, Ren, Xiaoguang, Xu, Peng, Yang, Zhicong, Dong, Shihua, Zhang, Baolong, Huang, Yanni, Li, Daqiang, Wang, Hailin, Yu, Wenqiang
Publicado 2021

Analysis of patients without and with an initial triple-negative breast cancer diagnosis in the phase 3 randomized ASCENT study of sacituzumab govitecan in metastatic triple-negati...

por O’Shaughnessy, Joyce, Brufsky, Adam, Rugo, Hope S., Tolaney, Sara M., Punie, Kevin, Sardesai, Sagar, Hamilton, Erika, Loirat, Delphine, Traina, Tiffany, Leon-Ferre, Roberto, Hurvitz, Sara A., Kalinsky, Kevin, Bardia, Aditya, Henry, Stephanie, Mayer, Ingrid, Zhu, Yanni, Phan, See, Cortés, Javier
Publicado 2022

Biodegradable nanoparticles induce cGAS/STING-dependent reprogramming of myeloid cells to promote tumor immunotherapy

por Podojil, Joseph R., Cogswell, Andrew C., Chiang, Ming-Yi, Eaton, Valerie, Ifergan, Igal, Neef, Tobias, Xu, Dan, Meghani, Khyati A., Yu, Yanni, Orbach, Sophia M., Murthy, Tushar, Boyne, Michael T., Elhofy, Adam, Shea, Lonnie D., Meeks, Joshua J., Miller, Stephen D.
Publicado 2022

Phenome-wide analysis identifies parent-of-origin effects on the human methylome associated with changes in the rate of aging

por Gao, Chenhao, Amador, Carmen, Walker, Rosie M., Campbell, Archie, Madden, Rebecca A, Adams, Mark J., Bai, Xiaomeng, Liu, Ying, Li, Miaoxin, Hayward, Caroline, Porteous, David J., Shen, Xueyi, Evans, Kathryn L., Haley, Chris S., McIntosh, Andrew M., Navarro, Pau, Zeng, Yanni
Publicado 2023

CLDN18.2 and 4-1BB bispecific antibody givastomig exerts antitumor activity through CLDN18.2-expressing tumor-directed T-cell activation

por Gao, Jing, Wang, Zhengyi, Jiang, Wenqing, Zhang, Yanni, Meng, Zhen, Niu, Yanling, Sheng, Zhen, Chen, Chan, Liu, Xuejun, Chen, Xi, Liu, Chanjuan, Jia, Keren, Zhang, Cheng, Liao, Haiyan, Jung, Jaeho, Sung, Eunsil, Chung, Hyejin, Zhang, Jingwu Z., Zhu, Andrew X., Shen, Lin
Publicado 2023

Safety and efficacy of ledipasvir‐sofosbuvir in black patients with hepatitis C virus infection: A retrospective analysis of phase 3 data

por Wilder, Julius M., Jeffers, Lennox J., Ravendhran, Natarajan, Shiffman, Mitchell L., Poulos, John, Sulkowski, Mark S., Gitlin, Norman, Workowski, Kimberly, Zhu, Yanni, Yang, Jenny C., Pang, Phillip S., McHutchison, John G., Muir, Andrew J., Howell, Charles, Kowdley, Kris, Afdhal, Nezam, Reddy, K. Rajender
Publicado 2015

The tarantula toxin β/δ-TRTX-Pre1a highlights the importance of the S1-S2 voltage-sensor region for sodium channel subtype selectivity

por Wingerd, Joshua S., Mozar, Christine A., Ussing, Christine A., Murali, Swetha S., Chin, Yanni K.-Y., Cristofori-Armstrong, Ben, Durek, Thomas, Gilchrist, John, Vaughan, Christopher W., Bosmans, Frank, Adams, David J., Lewis, Richard J., Alewood, Paul F., Mobli, Mehdi, Christie, Macdonald J., Rash, Lachlan D.
Publicado 2017

Identifying epigenetic biomarkers of established prognostic factors and survival in a clinical cohort of individuals with oropharyngeal cancer

por Langdon, Ryan, Richmond, Rebecca, Elliott, Hannah R., Dudding, Tom, Kazmi, Nabila, Penfold, Chris, Ingarfield, Kate, Ho, Karen, Bretherick, Andrew, Haley, Chris, Zeng, Yanni, Walker, Rosie M., Pawlita, Michael, Waterboer, Tim, Gaunt, Tom, Smith, George Davey, Suderman, Matthew, Thomas, Steve, Ness, Andy, Relton, Caroline
Publicado 2020

Epigenome‐wide analyses identify DNA methylation signatures of dementia risk

por Walker, Rosie M., Bermingham, Mairead L., Vaher, Kadi, Morris, Stewart W., Clarke, Toni‐Kim, Bretherick, Andrew D., Zeng, Yanni, Amador, Carmen, Rawlik, Konrad, Pandya, Kalyani, Hayward, Caroline, Campbell, Archie, Porteous, David J., McIntosh, Andrew M., Marioni, Riccardo E., Evans, Kathryn L.
Publicado 2020

Panoramic transcriptome analysis and functional screening of long noncoding RNAs in mouse spermatogenesis

por Li, Kai, Xu, Jiayue, Luo, Yanyun, Zou, Dingfeng, Han, Ruiqin, Zhong, Shunshun, Zhao, Qing, Mang, Xinyu, Li, Mengzhen, Si, Yanmin, Lu, Yan, Li, Pengyu, Jin, Cheng, Wang, Zhipeng, Wang, Fang, Miao, Shiying, Wen, Bo, Wang, Linfang, Ma, Yanni, Yu, Jia, Song, Wei
Publicado 2021

Non-invasive biomarkers of Fontan-associated liver disease

por Emamaullee, Juliet, Khan, Sara, Weaver, Carly, Goldbeck, Cameron, Yanni, George, Kohli, Rohit, Genyk, Yuri, Zhou, Shengmei, Shillingford, Nick, Sullivan, Patrick M., Takao, Cheryl, Detterich, Jon, Kantor, Paul F., Cleveland, John D., Herrington, Cynthia, Ram Kumar, S., Starnes, Vaughn, Badran, Sarah, Patel, Neil D.
Publicado 2021

Donor genetic variants as risk factors for thrombosis after liver transplantation: A genome‐wide association study

por Li, Yanni, Nieuwenhuis, Lianne M., Voskuil, Michiel D., Gacesa, Ranko, Hu, Shixian, Jansen, Bernadien H., Venema, Werna T. U., Hepkema, Bouke G., Blokzijl, Hans, Verkade, Henkjan J., Lisman, Ton, Weersma, Rinse K., Porte, Robert J., Festen, Eleonora A. M., de Meijer, Vincent E.
Publicado 2021

Single-cell architecture and functional requirement of alternative splicing during hematopoietic stem cell formation

por Wang, Fang, Tan, Puwen, Zhang, Pengcheng, Ren, Yue, Zhou, Jie, Li, Yunqiao, Hou, Siyuan, Li, Shuaili, Zhang, Linlin, Ma, Yanni, Wang, Chaojie, Tang, Wanbo, Wang, Xiaoshuang, Huo, Yue, Hu, Yongfei, Cui, Tianyu, Niu, Chao, Wang, Dong, Liu, Bing, Lan, Yu, Yu, Jia
Publicado 2022

The Gut Microbiome Dynamically Associates with Host Glucose Metabolism throughout Pregnancy: Longitudinal Findings from a Matched Case‐Control Study of Gestational Diabetes Mellitu...

por Sun, Zhonghan, Pan, Xiong‐Fei, Li, Xiao, Jiang, Limiao, Hu, Ping, Wang, Yi, Ye, Yi, Wu, Ping, Zhao, Bin, Xu, Jianguo, Kong, Mengmeng, Pu, Yanni, Zhao, Manying, Hu, Jianying, Wang, Jinfeng, Chen, Guo‐Chong, Yuan, Changzheng, Yu, Yongfu, Gao, Xiang, Zhao, Fangqing, Pan, An, Zheng, Yan
Publicado 2023

A Combined Pathway and Regional Heritability Analysis Indicates NETRIN1 Pathway Is Associated With Major Depressive Disorder

por Zeng, Yanni, Navarro, Pau, Fernandez-Pujals, Ana M., Hall, Lynsey S., Clarke, Toni-Kim, Thomson, Pippa A., Smith, Blair H., Hocking, Lynne J., Padmanabhan, Sandosh, Hayward, Caroline, MacIntyre, Donald J., Wray, Naomi R., Deary, Ian J., Porteous, David J., Haley, Chris S., McIntosh, Andrew M.
Publicado 2017

Prevalence of phase variable epigenetic invertons among host-associated bacteria

por Huang, Xueting, Wang, Juanjuan, Li, Jing, Liu, Yanni, Liu, Xue, Li, Zeyao, Kurniyati, Kurni, Deng, Yijie, Wang, Guilin, Ralph, Joseph D, De Ste Croix, Megan, Escobar-Gonzalez, Sara, Roberts, Richard J, Veening, Jan-Willem, Lan, Xun, Oggioni, Marco R, Li, Chunhao, Zhang, Jing-Ren
Publicado 2020

PTCH1 mutation promotes antitumor immunity and the response to immune checkpoint inhibitors in colorectal cancer patients

por Wang, Yanni, Chen, Huan, Jiao, Xi, Wu, Lihong, Yang, Ying, Zhang, Jiao, Wu, Lijia, Liu, Chang, Zhuo, Na, Li, Shuang, Gong, Jifang, Li, Jian, Zhang, Xiaotian, Wang, Xicheng, Peng, Zhi, Qi, Changsong, Wang, Zhenghang, Li, Jie, Li, Yan, Lu, Zhihao, Zhang, Henghui, Shen, Lin
Publicado 2021

Sacituzumab govitecan as second-line treatment for metastatic triple-negative breast cancer—phase 3 ASCENT study subanalysis

por Carey, Lisa A., Loirat, Delphine, Punie, Kevin, Bardia, Aditya, Diéras, Véronique, Dalenc, Florence, Diamond, Jennifer R., Fontaine, Christel, Wang, Grace, Rugo, Hope S., Hurvitz, Sara A., Kalinsky, Kevin, O’Shaughnessy, Joyce, Loibl, Sibylle, Gianni, Luca, Piccart, Martine, Zhu, Yanni, Delaney, Rosemary, Phan, See, Cortés, Javier
Publicado 2022

Expression-based subtypes define pathologic response to neoadjuvant immune-checkpoint inhibitors in muscle-invasive bladder cancer

por Robertson, A. Gordon, Meghani, Khyati, Cooley, Lauren Folgosa, McLaughlin, Kimberly A., Fall, Leigh Ann, Yu, Yanni, Castro, Mauro A. A., Groeneveld, Clarice S., de Reyniès, Aurélien, Nazarov, Vadim I., Tsvetkov, Vasily O., Choy, Bonnie, Raggi, Daniele, Marandino, Laura, Montorsi, Francesco, Powles, Thomas, Necchi, Andrea, Meeks, Joshua J.
Publicado 2023