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  1. 5241
    por Tonge, D. P., Gant, T. W.
    Publicado 2016
    “…CONCLUSIONS: The data contained within will be of particular use to researchers performing miRNA-based biomarker screening in plasma and allow shortlisting of candidates a priori to expedite discovery or reduce costs as required. …”
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    What is normal? Next generation sequencing-driven analysis of the human circulating miRNAOme
  2. 5242
    “…The clinical actionability of such findings varies, necessitating standardized frameworks for a priori decision making about their analysis. Genet Med 18 5, 467–475. …”
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    A semiquantitative metric for evaluating clinical actionability of incidental or secondary findings from genome-scale sequencing
  3. 5243
    “…For all analyses, we defined statistical significance a priori with a two-tailed alpha of 0.05. Statistical analyses were conducted using the Statistical Package for the Social Sciences (SPSS) version 15. …”
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    Better view on attitudes and perceived parental reactions behind waterpipe smoking among Iranian students
  4. 5244
    “…The specific aspects of care over which they disagreed were also described, and disagreements were classified a priori as major or minor. The primary outcome was the rate of disagreement over the handed over management plan. …”
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    Surgeon agreement at the time of handover, a prospective cohort study
  5. 5245
    “…The correlation between CTS-6 and the QuickDASH was concordant with the a priori formulated construct hypothesis (r 0.69) CONCLUSIONS: The standard Spanish version of the 6-item CTS symptoms scale showed good internal consistency, test-retest reliability and construct validity for outcomes assessment in CTS. …”
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    Reliability and construct validity of the Spanish version of the 6-item CTS symptoms scale for outcomes assessment in carpal tunnel syndrome
  6. 5246
    “…Parameters deemed essential to increase confidence in the published literature were clear, specific reporting of an a priori hypothesis and definition of primary outcome measure. …”
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    Ensuring transparency and minimization of methodologic bias in preclinical pain research: PPRECISE considerations
  7. 5247
    “…Two independent experts, who were blinded to the group allocations, validate the complication for each patient using an a priori classification. The secondary outcomes are to study the total number of postoperative complications, the real length of hospital stays, and the postoperative mortality between each group. …”
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    Perioperative hemodynamic optimization using the photoplethysmography in colorectal surgery (the PANEX3 trial): study protocol for a randomized controlled trial
  8. 5248
    “…The cell surface is equipped with a spontaneous curvature function, a proxy for the cell surface-cortex couple, that is a priori unknown, which the model “learns” from the thin section transmission electron micrograph image (2D) or the “seed and growth” model image (3D). …”
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    Modeling the Excess Cell Surface Stored in a Complex Morphology of Bleb-Like Protrusions
  9. 5249
    “…Four ICA components were spatially consistent with an a priori network framework based upon published meta-analyses of imaging correlates of AVH. …”
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    Functional MRI Evaluation of Multiple Neural Networks Underlying Auditory Verbal Hallucinations in Schizophrenia Spectrum Disorders
  10. 5250
    “…We suggest that a clear, definite hypothesis should be stated a priori and a commensurate statistical approach should accompany this hypothesis.…”
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    Literature Review and Comparison of Two Statistical Methods to Evaluate the Effect of Botulinum Toxin Treatment on Gait in Children with Cerebral Palsy
  11. 5251
    “…The Generalized Mixed Yule Coalescent (GMYC) model and two versions of the Bayesian species delimitation method BPP, with or without an a priori defined guide tree (v2.2 & v3.0), were used to evaluate species limits. …”
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    Species delimitation in northern European water scavenger beetles of the genus Hydrobius (Coleoptera, Hydrophilidae)
  12. 5252
    “…Qualitative analysis will be used to categorise behaviours and management strategies, and consensus will be based on a definition established a priori. ETHICS/DISSEMINATION: This study has been approved by the Institutional Review Board (IRB) of the University of Alabama at Birmingham (UAB). …”
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    Management of problematic behaviours among individuals on long-term opioid therapy: protocol for a Delphi study
  13. 5253
    “…METHODS AND ANALYSIS: A systematic review and meta-synthesis of qualitative studies. 5 databases will be searched using key search terms for qualitative research, evidence-based practice, clinical practice guidelines, osteoarthritis, beliefs, perceptions, barriers, enablers and adherence. A priori inclusion/exclusion criteria include availability of data from primary care clinicians, reports on views regarding management of osteoarthritis, and studies using qualitative methods for both data collection and analysis. …”
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    Barriers and enablers in primary care clinicians' management of osteoarthritis: protocol for a systematic review and qualitative evidence synthesis
  14. 5254
    “…METHODS: Phase II, III and long-term extension clinical trial data (April 2013 data-cut) from the tofacitinib RA programme were reviewed. OIs defined a priori included mycobacterial and fungal infections, multidermatomal herpes zoster and other viral infections associated with immunosuppression. …”
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    Tuberculosis and other opportunistic infections in tofacitinib-treated patients with rheumatoid arthritis
  15. 5255
    “…Conditions selected a priori included hypertension, diabetes, hyperlipidemia, coronary artery disease, stroke, rheumatic heart disease, and congestive heart failure. …”
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    Quality Improvement for Cardiovascular Disease Care in Low- and Middle-Income Countries: A Systematic Review
  16. 5256
    “…Multivariate projection technique was applied to analyse major sources of variation and collinearity within the cytokines dataset without a priori selecting potential relevant molecules. RESULTS: Twenty-nine severe traumatic brain injury patients undergoing intracranial pressure monitoring were studied. …”
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    Multivariate projection method to investigate inflammation associated with secondary insults and outcome after human traumatic brain injury: a pilot study
  17. 5257
    “…Nevertheless, the targeting system only reached a tiny proportion (≤1%) of the catchment population, and other poor and vulnerable people were missed. Low a priori set objectives and implementation problems—including a focus on easily identifiable groups (elderly, orphans), unclarity about pre-defined criteria, lack of transport for identification and insufficient motivation of community health workers—are likely to explain the low coverage. …”
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    Targeting the poorest in a performance-based financing programme in northern Cameroon
  18. 5258
    “…The blood oxygen level–dependent (BOLD) signal was measured in a priori brain regions involved in reward processing, including the caudate, nucleus accumbens, amygdala, anterior insula, and orbitofrontal cortex (n = 18 had analyzable fMRI data). …”
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    Increased colonic propionate reduces anticipatory reward responses in the human striatum to high-energy foods(1)(2)(3)
  19. 5259
    “…Despite a plethora of such mathematical models the ultimate goal, i.e., the “a priori” prediction of the radiation effect, has not yet been achieved. …”
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    Novel Biological Approaches for Testing the Contributions of Single DSBs and DSB Clusters to the Biological Effects of High LET Radiation
  20. 5260
    “…However, selection of EEG features used to answer experimental questions is typically determined a priori. The utility of machine learning was investigated as a computational framework for extracting the most relevant features from EEG data empirically. …”
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    Machine learning identification of EEG features predicting working memory performance in schizophrenia and healthy adults
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