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  1. 7361
    “…We will further examine the heterogeneity of treatment effects based on hypotheses specified a priori. In addition, we will conduct a mixed-methods process evaluation to assess reach, effectiveness, adoption, implementation, and maintenance of our direct admission intervention. …”
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    Comparative effectiveness of direct admission and admission through emergency departments for children: a randomized stepped wedge study protocol
  2. 7362
    “…We reduced the cut-off value for an abnormal FIT result from 20 or more to 10 or more μg hemoglobin/g feces a priori. All patients with abnormal FIT results were offered no-cost diagnostic colonoscopy. …”
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    Lower Abnormal Fecal Immunochemical Test Cut-Off Values Improve Detection of Colorectal Cancer in System-Level Screens
  3. 7363
    “…At enrollment, participants provided key demographic data including whether they were HCWs with direct patient contact. ILI was defined a priori as 1) having cough or sore throat plus 2) feeling feverish/having chills or having body aches/fatigue. …”
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    1715. Influenza-like Illness (ILI) Experience Among Healthcare Workers in Military Treatment Facilities: An Offshoot of the Pragmatic Assessment of Influenza Vaccine Effectiveness in the DoD (PAIVED) Study
  4. 7364
    “…All articles were screened by two independent reviewers using a priori criteria. Methodological quality and risk of bias were evaluated using a critical appraisal tool. …”
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    The prevalence of cardiac autonomic neuropathy in prediabetes: a systematic review
  5. 7365
    “…However, their safety, effectiveness, and cost-effectiveness are still a matter of debate. This a priori statistical analysis plan describes the methodology of the analysis for the STAR trial that assesses the (cost-)effectiveness of TESI during the acute stage of sciatica (< 8 weeks). …”
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    STeroids Against Radiculopathy (STAR) trial: a statistical analysis plan
  6. 7366
    “…Candidate predictors that were specified a priori were considered for inclusion in the model on the basis of previous prognostic scores and emerging literature describing routinely measured biomarkers associated with COVID-19 prognosis. …”
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    Development and validation of the ISARIC 4C Deterioration model for adults hospitalised with COVID-19: a prospective cohort study
  7. 7367
    “…In a multivariable logistic regression analysis, the risk-adjusted odds of survival to hospital discharge increased over time (biweekly change, adjusted odds ratio [aOR] 1.22, 95% CI 1.04–1.40, P = 0.02). Additionally, an a priori-defined explanatory model showed that after adjusting for both hospital occupancy and percent hospital capacity by COVID-19-positive individuals and persons under investigation (PUI), the temporal trend in risk-adjusted patient survival to hospital discharge remained the same (biweekly change, aOR 1.18, 95% CI 1.00–1.38, P = 0.04). …”
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    Surge effects and survival to hospital discharge in critical care patients with COVID-19 during the early pandemic: a cohort study
  8. 7368
    “…We used a construct approach, with a priori hypotheses regarding the expected direction and magnitude of PR changes between T1 and T2. …”
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    A quality indicator set for rehabilitation services for people with rheumatic and musculoskeletal diseases demonstrates adequate responsiveness in a pre–post evaluation
  9. 7369
    “…MATERIALS AND METHODS: The proposed selection procedure consists of several steps. A priori, we only include features that were found to be reproducible in a multicenter setting. …”
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    Plausibility and redundancy analysis to select FDG‐PET textural features in non‐small cell lung cancer
  10. 7370
    “…Interviews were transcribed and a priori CCM elements were coded using a directed content analysis approach at times 1 and 2. …”
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    Collaborative chronic care model implementation within outpatient behavioral health care teams: qualitative results from a multisite trial using implementation facilitation
  11. 7371
    “…Treatment effect estimates were generated using Cox proportional hazard models for each indication, in each database, and only for pairwise comparisons that met a priori study diagnostics. If estimates were homogeneous (I(2) < 40%), a meta-analysis across databases was performed and pooled hazard ratios reported. …”
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    Comparative Risk Assessment of Severe Uterine Bleeding Following Exposure to Direct Oral Anticoagulants: A Network Study Across Four Observational Databases in the USA
  12. 7372
    “…EXPOSURES: Age and sex were treated as a priori confounders while assessing correlates of ASD status according to (1) race/ethnicity, (2) social disadvantage, (3) first language spoken, (4) Education, Health and Care Plan or ASD Special Educational Needs and Disability support status, and (5) mediation analysis to assess how social disadvantage and language might affect ASD status. …”
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    Association of Race/Ethnicity and Social Disadvantage With Autism Prevalence in 7 Million School Children in England
  13. 7373
    “…Apps were evaluated for extent and quality of maternal health information and inclusivity of people of color using an a priori coding scheme. App usability was evaluated using the Mobile Application Rating Scale (MARS) score. …”
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    Comprehensively addressing postpartum maternal health: a content and image review of commercially available mobile health apps
  14. 7374
    “…The 3L and 5L were assessed for aspects of data quality including missing data, floor and ceiling effects, response consistency, and based on a priori hypotheses, associations with the Oswestry Disability Index (ODI), Pain-Visual Analogue Scales and Hopkins Symptom Checklist (HSCL-25). …”
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    Evaluation of the EQ-5D-3L and 5L versions in low back pain patients
  15. 7375
    “…This original study trial was registered a priori, on August 8, 2007. The current study hypothesis arose before inspection of the data. …”
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    Clinical risk factors associated with radiographic osteoarthritis progression among people with knee pain: a longitudinal study
  16. 7376
    “…Satisfaction was defined a priori as achieving a score above the 33rd percentile. …”
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    Evaluating the impact of social deprivation on Press Ganey® Outpatient Medical Practice Survey Scores
  17. 7377
    “…RESULTS: We coded deductively findings from 23 original studies using an a priori framework and subsequently conducted thematic analysis. …”
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    Adolescent condom use in Southern Africa: narrative systematic review and conceptual model of multilevel barriers and facilitators
  18. 7378
    “…The brain tumor immune microenvironment (TIME) continuously evolves during glioma progression, but a comprehensive characterization of the glioma-centric immune cell repertoire beyond a priori cell states is uncharted. In this study, we performed single-cell RNA-sequencing (scRNA-seq) and single cell- Assay for Transposase-Accessible Chromatin using sequencing (sc-ATAC-seq) on ~100,000 tumor-associated immune cells from seventeen isocitrate dehydrogenase (IDH) mutation classified primary and recurrent human gliomas and non-glioma brains (NGBs). …”
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    OTME-23. Single-cell transcriptomic and epigenomic immune landscape of isocitrate dehydrogenase stratified human gliomas
  19. 7379
    “…We developed a theory of change a priori for how we expect data use interventions to influence data use. …”
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    A realist systematic review of evidence from low- and middle-income countries of interventions to improve immunization data use
  20. 7380
    “…In radiomics, novel data-driven processes extract numerous visually imperceptible statistical features from the imaging data with no a priori assumptions on their correlation with biological processes. …”
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    Incorporating radiomics into clinical trials: expert consensus endorsed by the European Society of Radiology on considerations for data-driven compared to biologically driven quantitative biomarkers
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