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  1. 72161
    “…INTERPRETATION: These results provide evidence for the utility of a circulating metabolomics panel to identify children and adolescents at risk for future cardiovascular disease, to whom preventive measures and follow-up could be indicated.…”
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    Towards early risk biomarkers: serum metabolic signature in childhood predicts cardio-metabolic risk in adulthood
  2. 72162
    “…The sensitivity analysis included removal of outliers, separating adults and adolescents and the metaXL sensitivity analysis (studies are excluded if outside the pooled proportion confidence interval of the base case). …”
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    Treatment-seeking behaviour among people with opioid use disorder in the high-income countries: A systematic review and meta-analysis
  3. 72163
    “…The WHO estimates that around 20% of the world's children and adolescents have a mental health condition, a rate that is almost double compared to the general population. …”
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    Digital Mental Health for Young People: A Scoping Review of Ethical Promises and Challenges
  4. 72164
    “…CONCLUSION: This study highlights that the COVID-19 pandemic might have led to an increased rate of new-onset T1DM, T2DM, and DKA in children and adolescents compared to a similar time frame in the prior 2 years. …”
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    SARS-CoV-2 infection in hospitalized children with type 1 and type 2 diabetes
  5. 72165
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    Developmental Relations Between Internalising Problems and ADHD in Childhood: a Symptom Level Perspective
  6. 72166
    “…Reductions were largest among men and people living in the most deprived neighbourhoods, while an increase in all-episode self-harm was observed for adolescents aged 10–17. INTERPRETATION: Reductions in primary care-recorded self-harm persisted to May 2021, though they were less marked than in April 2020 during the first national lockdown. …”
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    Temporal trends in primary care-recorded self-harm during and beyond the first year of the COVID-19 pandemic: Time series analysis of electronic healthcare records for 2.8 million patients in the Greater Manchester Care Record
  7. 72167
    “…Here we studied effects of genetic stress susceptibility, approximated by the polygenic risk score (PRS) for post-traumatic-stress-disorder (PTSD), on preadolescent suicidality in participants from the Adolescent Brain Cognitive Development (ABCD) Study®. …”
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    Contributions of PTSD polygenic risk and environmental stress to suicidality in preadolescents
  8. 72168
    “…BACKGROUND/AIM: We aimed to determine the presence of subclinical atherosclerosis using carotid intima-media thickness (CIMT) and biochemical parameters in children and adolescents with congenital adrenal hyperplasia (CAH). …”
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    The relationship of carotid intima-media thickness with anthropometric and metabolic parameters in patients with classic congenital adrenal hyperplasia
  9. 72169
    “…CONCLUSIONS: School enjoyment is a potentially modifiable risk factor that may affect educational attainment of adolescents with depressive or externalising symptoms.…”
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    The role of school enjoyment and connectedness in the association between depressive and externalising symptoms and academic attainment: Findings from a UK prospective cohort study
  10. 72170
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    Neural Responses to Fluoxetine in Youths with Disruptive Behavior and Trauma Exposure: A Pilot Study
  11. 72171
    “…Thus, the current study examined the convergent validity of a repeated Illinois Agility (RIA) protocol with the repeated T-agility protocol, and the repeatability of the RIA protocol in adolescent Rugby League players. Furthermore, aerobic capacity and anaerobic and COD performance were assessed to determine whether these physical qualities were important contributors to the RIA protocol. …”
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    Convergent validity and reliability of a novel repeated agility protocol in junior rugby league players
  12. 72172
    “…All centers were multidisciplinary and included adolescents and young adults (transitional) primarily recruited through healthcare services. …”
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    ITAlian partnership for psychosis prevention (ITAPP): Improving the mental health of young people
  13. 72173
    por Lei, Ting, Qian, Hu, Lei, Pengfei, Hu, Yihe
    Publicado 2021
    “…Osteosarcoma has been the most common malignant bone tumor in children and adolescents, while the 5‐y survival of osteosarcoma patients gained no significant improvement over the past decades. …”
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    Ferroptosis‐related gene signature associates with immunity and predicts prognosis accurately in patients with osteosarcoma
  14. 72174
    por Hviid, Anders, Laksafoss, Anna
    Publicado 2021
    “…We evaluated the association between a human papillomavirus vaccine, a non-live vaccine primarily administered to pre-adolescent females, and non-targeted infectious disease in a high-income country. …”
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    Quadrivalent human papillomavirus vaccination and non-targeted infectious disease hospitalisation: Population-based self-controlled case series analysis
  15. 72175
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    Sex and the streets: the open secret of sexual abuse among Pakistan’s two million street children
  16. 72176
    “…Dose simulations demonstrated a 77%–83% probability of attaining a trough target of 1 mg/L with a dose of 300 mg every 12 h for two doses then 300 mg once daily (OD) in children aged 6–11 years; and 86%–88% with a dose of 400 mg every 12 h for two doses then 400 mg OD in adolescents aged 12–17 years. This dose scheme also yielded a 90% probability of achieving an AUC of 30 mg·h/L. …”
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    Clinical pharmacokinetics and dose recommendations for posaconazole gastroresistant tablets in children with cystic fibrosis
  17. 72177
    “…BACKGROUND: In the BREATHE trial weekly azithromycin decreased the rate of acute respiratory exacerbations (AREs) compared to placebo among children and adolescents with HIV-associated chronic lung disease (CLD) taking antiretroviral therapy (ART). …”
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    Effect of azithromycin on incidence of acute respiratory exacerbations in children with HIV taking antiretroviral therapy and co-morbid chronic lung disease: a secondary analysis of the BREATHE trial
  18. 72178
    por Mukherjee, Sayanti, Wei, Zhiyuan
    Publicado 2021
    “…Our results also indicate that non-Hispanics, native Hawaiian or Pacific islanders, and adolescents aged 15-29 years, residing in the large metropolitan areas, are more vulnerable to suicides compared to those living in the medium/small metropolitan areas. …”
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    Suicide disparities across metropolitan areas in the US: A comparative assessment of socio-environmental factors using a data-driven predictive approach
  19. 72179
    “…Data from 40 participants (obese children and adolescents) having the plasma metabolites data related to the changes in BMI z-scores after 6-month lifestyle intervention were analyzed. …”
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    Changes in Plasma Choline and the Betaine-to-Choline Ratio in Response to 6-Month Lifestyle Intervention Are Associated with the Changes of Lipid Profiles and Intestinal Microbiota: The ICAAN Study
  20. 72180
    “…BACKGROUND: Stigma and limited mental health literacy impede adolescents getting the help they need for depressive symptoms. …”
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    Feasibility of a serious game coupled with a contact-based session led by lived experience workers for depression prevention in high-school students
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