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  1. 72481
    “…BACKGROUND: Osteosarcoma (OS) is the most common malignant bone tumor with a high incidence in children and adolescents. Frequent tumor metastasis and high postoperative recurrence are the most common challenges in OS. …”
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    CD248 promotes migration and metastasis of osteosarcoma through ITGB1-mediated FAK-paxillin pathway activation
  2. 72482
    por Ali, Heba A.
    Publicado 2023
    “…RESULTS: This single-center, retrospective study enrolled eighty hospitalized children and adolescents under the age of 18 years with coronavirus type 2 infections, who were divided according to the level of clinical severity into severe and non-severe groups. …”
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    Major determinant factors of pediatric COVID-19 severity; a single center study
  3. 72483
    “…Construct validity was supported by PARQ and CARQ scores for medications, exercise and splints showing a fair to good correlation with the Global Adherence Assessment (GAA) and selected PedsQL scales. Adolescents showed poorer adherence than children. About one third of the parents and children reported medication errors. …”
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    Adherence, helpfulness and barriers to treatment in juvenile idiopathic arthritis – data from a German Inception cohort
  4. 72484
    “…The patients were categorized as paucisymptomatic/moderate (55.6%) or severe/critical (44.5%) according to established diagnostic criteria and further stratified into the categories of infants (1–12 months), children (1–12 years), and adolescents (>12 years). We assessed SARS-CoV-2-specific RBD antibodies (Ab), neutralizing antibodies (nAb), and circulating cytokines/chemokines in the plasma, and the SARS-CoV-2-specific immune response was measured in PBMCs by gene expression and secretome analyses. …”
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    The Immunological Profile of SARS-CoV-2 Infection in Children Is Linked to Clinical Severity and Age
  5. 72485
    “…INTRODUCTION: Relapsed and refractory B-cell acute lymphoblastic leukaemia (R/R-B-ALL) is linked to a significant relapse rate after allogeneic haematopoietic cell transplantation (allo-HCT) in children, adolescents and young adults (CAYA). No standard treatment has been established to prevent relapse after allo-HCT for R/R-B-ALL, which is an unmet medical need. …”
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    Safety and efficacy of post-haematopoietic cell transplantation maintenance therapy with blinatumomab for relapsed/refractory CD19-positive B-cell acute lymphoblastic leukaemia: protocol for a phase I–II, multicentre, non-blinded, non-controlled trial (JPLSG SCT-ALL-BLIN21)
  6. 72486
    “…In the multivariate analysis, a younger age of parents (aOR: 2.40, CI: [1.50–3.83]), a higher level of fear that “a member of my family” could contract COVID-19 (aOR: 2.35, CI: [1.38–4.02]), a higher level of perceived vulnerability to COVID-19 within the family (aOR: 1.70, CI: [1.005–2.2881]), a higher level of perceived susceptibility to COVID-19 within the family (aOR: 3.07, CI: [1.80–5.23]), and a history of vaccination against COVID-19 among parents (aOR: 16.47, CI: [8.39–32.33]), CONCLUSION: Were all significantly associated with the intention of parents to have their children or adolescents vaccinated. According to the different explanatory factors of the will to have their children vaccinated, an emphasis on the health education of parents who are prone to refusal or hesitation of the vaccine, by addressing the common reasons for the refusal of the vaccine and highlight the vaccine's benefits. …”
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    P056 - Determinants of Parents’ Intention to Vaccinate Their Children Aged 12–17 Years against COVID-19 in North Kivu (DRC)
  7. 72487
    “…To assess accuracy of the reported data on midwives’ authorization to provide BEmONC services, we reviewed national regulatory documents and compared with reported country-specific data in Countdown to 2030 and the World Health Organization Maternal, Newborn, Child and Adolescent Health Policy Survey. To assess whether authorization demonstrates convergent validity with midwives’ skills, training, and performance of BEmONC signal functions, we surveyed 1257 midwives/midwifery professionals and assessed variance. …”
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    Authorization of midwives to perform basic emergency obstetric and newborn care signal functions in Argentina, Ghana, and India: A multi-country validation study of a key global maternal and newborn health indicator
  8. 72488
    “…This study investigated the diet quality, nutrition imbalances and nutrition status among young children,adolescents and adults with CD who were referred to several hospitals in Lebanon. …”
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    Nutritional status, nutrient imbalances, food-related behaviors and dietary supplements use among patients with celiac disease on a gluten free diet in Lebanon: a national cross-sectional study
  9. 72489
    “…However, there are no studies examining whether SES moderates the association between these neurodevelopmental disorders (ND) and the academic achievement of children and adolescents. The present investigation examined the impact of ADHD and SLD on academic performance in 1,287 Spanish students aged 5–17 from a low-middle (LM)- and a high-income population, when adjusted for comorbidity and demographic factors that may influence educational functioning. …”
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    The impact of attention-deficit/hyperactivity disorder and specific learning disorders on academic performance in Spanish children from a low-middle- and a high-income population
  10. 72490
    “…CONCLUSION: These findings could provide clues for the early identification of paediatric patients with prolonged viral shedding and could enrich the evidence for the development of prevention and control strategies, especially vaccination policies for children and adolescents.…”
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    Factors associated with negative conversion of viral RNA in hospitalized children infected with SARS-CoV-2 Omicron variant in Shanghai, China: a retrospective analysis
  11. 72491
    “…The study suggests that a more effective approach may be developed in future to target adolescent mothers, as maternal nutrition and education are age-dependent variables. …”
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    A predictive modelling approach to illustrate factors correlating with stunting among children aged 12–23 months: a cluster randomised pre-post study
  12. 72492
    “…OBJECTIVE: To determine whether 8 weeks of intranasal OXT (vs 8 weeks of placebo) promotes weight loss in children, adolescents, and young adults with hypothalamic obesity. …”
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    A Pilot Randomized Clinical Trial of Intranasal Oxytocin to Promote Weight Loss in Individuals With Hypothalamic Obesity
  13. 72493
    “…OBJECTIVES: This study examines the relationship between social engagement and loneliness in female and male autistic children and adolescents in school-based social settings. Secondary aims sought to explore the emergence of loneliness across different age groups and differences in social engagement and loneliness between genders. …”
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    Social engagement and loneliness in school-age autistic girls and boys
  14. 72494
    por Simões Cunha, Mafalda, Amaral, Rita, Pereira, Ana Margarida, Almeida, Rute, Alves-Correia, Magna, Loureiro, Cláudia Chaves, Lopes, Cristina, Carvalho, Joana, Ribeiro, Carmelita, Vidal, Carmen, Antolín-Amérigo, Dario, Pinto, Diana, Ferreira-Magalhães, Manuel, Vasconcelos, Maria João, Lozoya, Carlos, Santos, Natacha, Cardia, Francisca, Taborda-Barata, Luís, Ferreira, Rosário, Morais Silva, Pedro, Ferreira, Tania Monteiro, Câmara, Raquel, Silva, Eurico, Bordalo, Diana, Guimarães, Cristina, Calix, Maria José, da Silva, Sofia, Marques, Maria Luís, Morete, Ana, Nunes, Carlos, Vieira, Cláudia, Páscoa, Rosália, Alves, Adelaide, Marques, José Varanda, Reis, Bruno, Monteiro, Luís, Monteiro, Rosário, Cepa, Margarida, Valentim, Bruno, Coelho, Daniela Sousa, Fernandes, Sara, Meireles, Patrícia, Aguiar, Margarida Abreu, Mourão, Ana Rita, Fonseca, Joao A, Jácome, Cristina
    Publicado 2023
    “…METHODS: This is a secondary analysis of the INSPIRERS studies. A total of 614 adolescents and adults with persistent asthma (32.6±16.9 years, 64.7% female) were recruited from 30 primary care centres and 32 allergy, pulmonology and paediatric clinics. …”
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    Symptoms of anxiety and depression in patients with persistent asthma: a cross-sectional analysis of the INSPIRERS studies
  15. 72495
    “…In many cases, these factors occur earlier in life and contribute to adolescent or earlier adulthood depressive episodes, where the onset was related to adverse childhood events, maladaptive personality traits, reproductive events, or other factors. …”
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    Biological factors influencing depression in later life: role of aging processes and treatment implications
  16. 72496
    “…The reasons for this include vaccine-associated myocarditis having a higher incidence in young adults and adolescents, typically no involvement of other organs in vaccine-associated myocarditis, and based on comparisons to non-COVID viral myocarditis an inherently more benign clinical course.…”
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    Vaccination-Associated Myocarditis and Myocardial Injury
  17. 72497
    “…BACKGROUND: Adolescent girls and young women (AGYW) are at high risk of contracting HIV and exchanging sex for financial or material support heightens their risk. …”
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    Facilitators and barriers to engaging with the DREAMS initiative among young women who sell sex aged 18–24 in Zimbabwe: a qualitative study
  18. 72498
    “…While tetanus-diphtheria-acellular pertussis (Tdap) vaccines for adolescents and adults were licensed in 2005 and immunization strategies proposed, the burden of pertussis in this population remains under-recognized mainly due to atypical disease presentation, undermining efforts to optimize protection through vaccination. …”
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    Development of an algorithm for finding pertussis episodes in a population-based electronic health record database
  19. 72499
    “…Adults had more injuries related to aerial, whereas adolescents had more related to ground disciplines (χ(2) (2)=10.62, p=0.005) and non-time loss injuries (χ(2) (1)=5.45, p=0.02). …”
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    Untangling risk factors including discipline-specific exposure for injuries in preprofessional and professional circus artists in the USA
  20. 72500
    “…Due to understanding and behavioral difficulties, it might be difficult to administer motor assessment measures to children and adolescents with ASD. To evaluate motor challenges in this population, including gait and dynamic balance issues, the timed up and go test (TUG) may be a simple, easy to apply, quick, and inexpensive tool. …”
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    Reliability and agreement of the timed up and go test in children and teenagers with autism spectrum disorder
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