Materias dentro de su búsqueda.
Mostrando 81 - 95 Resultados de 95 Para Buscar '"almanac"', tiempo de consulta: 0.31s Limitar resultados
  1. 81
    “…Results, illustrated using NCI60 and NCI-ALMANAC databases, demonstrate that the ensemble approaches can provide significant improvement in prediction performance as compared to individual models. …”
    Enlace del recurso
    Enlace del recurso
    Enlace del recurso
    Online Artículo Texto
    Investigation of REFINED CNN ensemble learning for anti-cancer drug sensitivity prediction
  2. 82
    “…Then, the clustering results are leveraged to discover effective multi-targeted drug combinations, which are also supported by more evidence using GDSC and ALMANAC databases. The potency and synergy levels of selective drug combinations are corroborated against monotherapy in three cell lines for acute myeloid leukaemia in vitro. …”
    Enlace del recurso
    Enlace del recurso
    Enlace del recurso
    Online Artículo Texto
    Bipartite network models to design combination therapies in acute myeloid leukaemia
  3. 83
    “…Here, we set out to examine the impact of different methodological choices on the performance of multimodal DL-based drug synergy prediction methods, including the use of different input data types, preprocessing steps and model architectures. Focusing on the NCI ALMANAC dataset, we found that feature selection based on prior biological knowledge has a positive impact—limiting gene expression data to cancer or drug response-specific genes improved performance. …”
    Enlace del recurso
    Enlace del recurso
    Enlace del recurso
    Online Artículo Texto
    A systematic evaluation of deep learning methods for the prediction of drug synergy in cancer
  4. 84
    por Wärnberg, F, Bundred, N
    Publicado 2002
    “…Several randomised controlled trials (including ALMANAC) are currently underway. British Journal of Cancer (2002) 87, 691–693. doi:10.1038/sj.bjc.6600557 www.bjcancer.com © 2002 Cancer Research UK…”
    Enlace del recurso
    Enlace del recurso
    Enlace del recurso
    Texto
    Will early detection of non-axillary sentinel nodes affect treatment decisions?
  5. 85
    “…Moreover, rs2144025 was significantly associated with ESR1 mRNA levels in the Brain eQTL Almanac and in brain regions in the Genotype-Tissue Expression project. …”
    Enlace del recurso
    Enlace del recurso
    Enlace del recurso
    Online Artículo Texto
    Intronic SNP in ESR1 encoding human estrogen receptor alpha is associated with brain ESR1 mRNA isoform expression and behavioral traits
  6. 86
    “…Then, we performed a query in Genotype-tissue Expression (GTEx), Brain eQTL Almanac (Braineac) databases and Blood expression quantitative trait loci (eQTL) browser. …”
    Enlace del recurso
    Enlace del recurso
    Enlace del recurso
    Online Artículo Texto
    IL1B polymorphism is associated with essential tremor in Chinese population
  7. 87
    “…CONCLUSIONS: The performance of SYNPRED rivals that of the existing methods that tackle the same problem, yielding unbiased results trained with one of the most comprehensive datasets available (NCI ALMANAC). The leveraging of different reference models allowed deeper insights into which of them can be more appropriately used for synergy prediction. …”
    Enlace del recurso
    Enlace del recurso
    Enlace del recurso
    Online Artículo Texto
    SYNPRED: prediction of drug combination effects in cancer using different synergy metrics and ensemble learning
  8. 88
    “…We then integrated these with baseline transcriptomics from CCLE to build robust machine learning models to predict cell line sensitivity from NCI-ALMANAC across nine cancer types, with model accuracy R(2) ~ 0.75–0.9 after feature selection using elastic-net regression. …”
    Enlace del recurso
    Enlace del recurso
    Enlace del recurso
    Online Artículo Texto
    Combined kinome inhibition states are predictive of cancer cell line sensitivity to kinase inhibitor combination therapies
  9. 89
    “…Moreover, rs910083-C was implicated as a cis-methylation quantitative trait locus (QTL) variant associated with higher DNMT3B methylation in fetal brain (N=166, P=2.3×10(−26)) and a cis-expression QTL variant associated with higher DNMT3B expression in adult cerebellum from the Genotype-Tissue Expression project (N=103, P=3.0×10(−6)) and the independent Brain eQTL Almanac (N=134, P=0.028). This novel DNMT3B cis-acting QTL variant highlights the importance of genetically influenced regulation in brain on the risks of nicotine dependence, heavy smoking, and consequent lung cancer.…”
    Enlace del recurso
    Enlace del recurso
    Enlace del recurso
    Online Artículo Texto
    Genome-wide association study across European and African American ancestries identifies a SNP in DNMT3B contributing to nicotine dependence
  10. 90
    “…FUNDING: This work received support from the National Cancer Institute (1R01 CA102713 (CLB), https://www.nih.gov/about-nih/what-we-do/nih-almanac/national-cancer-institute-nci; and two Pilot Project grants from the American Cancer Society's Institutional Grant Award to the University of South Carolina (IRG-13–043–01) https://www.cancer.org/ (SH; BS).…”
    Enlace del recurso
    Enlace del recurso
    Enlace del recurso
    Online Artículo Texto
    Consequences to patients, clinicians, and manufacturers when very serious adverse drug reactions are identified (1997–2019): A qualitative analysis from the Southern Network on Adverse Reactions (SONAR)
  11. 91
    por Lombard, Fabien, Bourdin, Guillaume, Pesant, Stéphane, Agostini, Sylvain, Baudena, Alberto, Boissin, Emilie, Cassar, Nicolas, Clampitt, Megan, Conan, Pascal, Da Silva, Ophélie, Dimier, Céline, Douville, Eric, Elineau, Amanda, Fin, Jonathan, Flores, J. Michel, Ghiglione, Jean-François, Hume, Benjamin C. C., Jalabert, Laetitia, John, Seth G., Kelly, Rachel L., Koren, Ilan, Lin, Yajuan, Marie, Dominique, McMinds, Ryan, Mériguet, Zoé, Metzl, Nicolas, Paz-García, David A., Pedrotti, Maria Luiza, Poulain, Julie, Pujo-Pay, Mireille, Ras, Joséphine, Reverdin, Gilles, Romac, Sarah, Rouan, Alice, Röttinger, Eric, Vardi, Assaf, Voolstra, Christian R., Moulin, Clémentine, Iwankow, Guillaume, Banaigs, Bernard, Bowler, Chris, de Vargas, Colomban, Forcioli, Didier, Furla, Paola, Galand, Pierre E., Gilson, Eric, Reynaud, Stéphanie, Sunagawa, Shinichi, Sullivan, Matthew B., Thomas, Olivier P., Troublé, Romain, Thurber, Rebecca Vega, Wincker, Patrick, Zoccola, Didier, Allemand, Denis, Planes, Serge, Boss, Emmanuel, Gorsky, Gaby
    Publicado 2023
    “…Environmental context data were obtained from taxonomic registries, gazetteers, almanacs, climatologies, operational biogeochemical models, and satellite observations. …”
    Enlace del recurso
    Enlace del recurso
    Enlace del recurso
    Online Artículo Texto
    Open science resources from the Tara Pacific expedition across coral reef and surface ocean ecosystems
  12. 92
    por Ali, Akleema, Maharajh, Hari D.
    Publicado 2003
    “…Public holidays and lunar phases were obtained through almanacs for each year; and school vacation period was determined by reference to a school academic calendar. …”
    Enlace del recurso
    Enlace del recurso
    Texto
    Time of the year and absconding from a psychiatric hospital in Trinidad
  13. 93
    “…The results showed that in grasslands with different degrees of desertification, Stellera chromosome (3.90), Thermopsis lanceolate (3.52) and Aster almanacs (3.99) had larger niche widths, which were wide-area species of plant communities in the desertification area. …”
    Enlace del recurso
    Enlace del recurso
    Enlace del recurso
    Online Artículo Texto
    Ecological Niche and Interspecific Association of Plant Communities in Alpine Desertification Grasslands: A Case Study of Qinghai Lake Basin
  14. 94
    por Zischka, K A
    Publicado 2018
    “…Beginning with the basics of positional astronomy, this guide moves on to the more complex math necessary to understand the ephemerides, tables showing the future positions of the stars and planets. These astronomical almanacs were the satellite navigation of their day. …”
    Enlace del recurso
    Enlace del recurso
    Astronavigation: a method for determining exact position by the stars
  15. 95
    “…METHODS: Data for this retrospective study was provided from Statistical Almanacs of Inpatient Services (2001-2006). Hospitals in each of the 81 provinces were grouped into two categories: public and private. …”
    Enlace del recurso
    Enlace del recurso
    Enlace del recurso
    Texto
    The change in capacity and service delivery at public and private hospitals in Turkey: A closer look at regional differences
Herramientas de búsqueda: RSS