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20341por Guo, Shiwei, Shi, Xiaohan, Gao, Suizhi, Hou, Qunxing, Jiang, Lisha, Li, Bo, Shen, Jing, Wang, Huan, Shen, Shuo, Zhang, GuoXiao, Pan, Yaqi, Liu, Wuchao, Xu, Xiongfei, Zheng, Kailian, Shao, Zhuo, Jing, Wei, Lin, Ling, Li, Gang, Jin, Gang“…Among these, class 1 (characterized by the Fanconi anemia pathway) achieved the best outcome, while class 2 (involved in the platinum drug resistance pathway) suffered from the worst prognosis. …”
Publicado 2021
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20342por Mansfield, Aaron S., Hong, David S., Hann, Christine L., Farago, Anna F., Beltran, Himisha, Waqar, Saiama N., Hendifar, Andrew E., Anthony, Lowell B., Taylor, Matthew H., Bryce, Alan H., Tagawa, Scott T., Lewis, Karl, Niu, Jiaxin, Chung, Christine H., Cleary, James M., Rossi, Michael, Ludwig, Carrianne, Valenzuela, Ricardo, Luo, Yan, Aggarwal, Rahul“…At the RP2D, grade 3/4 adverse events included anemia (17%), thrombocytopenia (15%), and elevated aspartate aminotransferase (8%). …”
Publicado 2021
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20343por Mattebo, Alexander, Sen, Taha, Jassinskaja, Maria, Pimková, Kristýna, Prieto González-Albo, Isabel, Alattar, Abdul Ghani, Ramakrishnan, Ramprasad, Lang, Stefan, Järås, Marcus, Hansson, Jenny, Soneji, Shamit, Singbrant, Sofie, van den Akker, Emile, Flygare, Johan“…While lack of Ypel4 did not affect steady-state TED in the bone marrow or spleen, the anemia-recovering capacity of Ypel4-null cells was diminished. …”
Publicado 2021
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20344“…The ADC value of the EG before treatment was (0.752 ± 0.021) × 10(−3) mm(2)/s, which was visibly lower than that after treatment ((1.365 ± 0.058) × 10(−3) mm(2)/s) and that in the CG ((1.856 ± 0.079)) × 10(−3) mm(2)/s), showing statistically obvious differences (P < 0.05). The incidence of anemia, oral reactions, hypertension, and gastrointestinal reaction in the EG after treatment was 61.46%, 45.35%, 47.28%, and 39.67%, respectively. …”
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20345“…Patient: Female, 57-year-old Final Diagnosis: Acquired thrombocytopenic purpura • influenza A virus infection Symptoms: Hypoxemia Medication:— Clinical Procedure: Plasma exchange Specialty: Critical Care Medicine • Hematology OBJECTIVE: Rare disease BACKGROUND: Thrombotic microangiopathy, characterized by microangiopathic hemolytic anemia, thrombocytopenia, and organ damage by microvascular thrombosis, has a high mortality rate; therefore, early diagnosis and treatment are important. …”
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20346“…The main side effects were myelosuppression, including granulocytopenia, thrombocytopenia, and anemia. Among patients with grade 1 side effects or above, 28 patients (73.68%) had myelosuppression, and 13 patients (34.21%) had gastrointestinal reactions. …”
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20347por Wennberg, Alexandra M, Ding, Mozhu, Ebeling, Marcus, Hammar, Niklas, Modig, Karin“…Compared to the largest class, the Reference class (81.7%), all other classes were associated with increased risk of both frailty and mortality. The Anemia class (5.8%), characterized by comparatively lower iron markers and higher inflammatory markers, had hazard ratio (HR) = 1.54, 95% confidence interval (CI) 1.38, 1.73 for frailty and HR = 1.76, 95% CI 1.65, 1.87 for mortality. …”
Publicado 2021
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20348por Tsagkataki, Eleni S., Flamourakis, Mathaios E., Gkionis, Ioannis G., Giakoumakis, Michail I., Delimpaltadakis, Georgios N., Kazamias, Georgios M., Giannikaki, Elpida S., Christodoulakis, Manousos S.“…CASE PRESENTATION: We present the case of a 53-year-old Caucasian male who was hospitalized for anemia. Computerized tomography of the abdomen depicted a mass between the pylorus of the stomach and the first part of the duodenum. …”
Publicado 2021
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20349por Zhu, Jianquan, Zhang, Yu, Wang, Meng, Zhang, Zhenfa, Yue, Dongsheng, Liu, Shichang, Pan, Yi, Wang, Changli“…The most common adverse events were neutropenia, anemia, and leukopenia. CONCLUSIONS: This study preliminarily indicated a favorable effect of nab-paclitaxel plus carboplatin as neoadjuvant therapy without significant adverse events for stage IIIA-N2 squamous cell carcinoma of the lung. …”
Publicado 2021
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20350“…However, complications have been reported, especially following high and long-term use, including nerve damage, spontaneous pneumo-mediastinum, myocardial infarction, and macrocytic anemia. CASE REPORT: We report a case of a 19-year-old previously healthy man with occasional recreational use of nitrous oxide of up to 10 times within recent months, who presented with severe peripheral neuropathy. …”
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20351por Vu, Khoa, Zhou, Jiani, Everhart, Alexander, Desai, Nihar, Herrin, Jeph, Jena, Anupam B., Ross, Joseph S., Shah, Nilay D., Karaca-Mandic, Pinar“…We examined de-adoption of erythropoiesis-stimulating agents (ESA) in anemia treatment among patients with chronic kidney disease (CKD) following new clinical evidence of harm and ineffectiveness (the TREAT trial) and the FDA’s revision of its safety warning. …”
Publicado 2021
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20352por Shujaa Edin, Hareth Y., AL-Haj, Nagi A., Rasedee, Abdullah, Banu Alitheen, Noorjahan, Abdul Kadir, Arifah, Wun How, Chee, Sulaiman Rahman, Heshu, AL-Shwyeh, Hussah Abdullah“…Erythropoietin (EPO) is widely used to treat anemia in patients undergoing chemotherapy for cancers. …”
Publicado 2021
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20353“…However, only a small proportion of the patients with anemia (3.9 %), hypoalbuminemia (4.1 %), and abnormal serum potassium levels (3.5 %) required clinical intervention after surgery. …”
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20354por Spedicati, Beatrice, Cocca, Massimiliano, Palmisano, Roberto, Faletra, Flavio, Barbieri, Caterina, Francescatto, Margherita, Mezzavilla, Massimo, Morgan, Anna, Pelliccione, Giulia, Gasparini, Paolo, Girotto, Giorgia“…Of particular interest is a case presenting with a FANCL biallelic LoF variant and a positive diepoxybutane test but lacking a full Fanconi anemia phenotypic spectrum. Identifying KO subjects displaying expected phenotypes suggests that the lack of correct genetic diagnoses may lead to inappropriate and delayed treatment. …”
Publicado 2021
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20355por Xu, Lan-Ping, Lu, Pei-Hua, Wu, De-Pei, Sun, Zi-Min, Liu, Qi-Fa, Han, Ming-Zhe, Zhang, Xi, Song, Yong-Ping, Song, Xian-Min, Hu, Jian-da, Huang, He, Lai, Yong-Rong, Wan, Ding-Ming, Chen, Jing, Li, Chun-Fu, Xia, Ling-Hui, Wang, Jing-Bo, Liu, Dai-Hong, Huang, Xiao-Jun“…The most common indications for allogeneic HSCT for malignant disease were acute myeloid leukemia (AML) (37%) and acute lymphoblastic leukemia (ALL) (24%), and the largest proportion of non-malignant diseases comprised aplastic anemia (AA) (13%). Multiple stem cell source composed 70% of HID and 28% of MSD, which was typical in China. …”
Publicado 2021
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20356por Nangaku, Masaomi, Kondo, Kazuoki, Ueta, Kiichiro, Kokado, Yoshimasa, Kaneko, Genki, Matsuda, Hiroki, Kawaguchi, Yutaka, Komatsu, Yasuhiro“…The findings suggest that vadadustat can be an alternative to ESA in the management of anemia in Japanese hemodialysis patients receiving ESA (ClinicalTrials.gov, NCT03439137).…”
Publicado 2021
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20357por Bezerra, Ohanna Cavalcanti de Lima, Alvarado-Arnez, Lucia Elena, Mabunda, Nédio, Salomé, Graça, de Sousa, Amina, Kehdy, Fernanda de Souza Gomes, Sales-Marques, Carolinne, Manta, Fernanda Saloum de Neves, Andrade, Rafaela Mota, Ferreira, Laís Pereira, Leal-Calvo, Thyago, Cardoso, Cynthia Chester, Nunes, Kelly, Gouveia, Mateus H., Mbulaiteve, Sam M., Yeboah, Edward D., Hsing, Ann, Latini, Ana Carla Pereira, Leturiondo, André Luiz, Rodrigues, Fabíola da Costa, Noronha, Ariani Batista, Ferreira, Cynthia de Oliveira, Talhari, Carolina, Rêgo, Jamile Leão, Castellucci, Léa Cristina de Carvalho, Tarazona-Santos, Eduardo, de Carvalho, Elizeu Fagundes, Meyer, Diogo, Pinheiro, Roberta Olmo, Jani, Ilesh V., Pacheco, Antonio Guilherme, Moraes, Milton Ozório“…Due to Plasmodium selection, mutations for PK deficiency, which leads to hemolytic anemia, are associated with resistance to malaria in sub-Saharan Africa and with susceptibility to intracellular pathogens in experimental models. …”
Publicado 2021
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20358por Zou, Jieya, Yang, Xiaojuan, Duan, Jiajun, Wang, Ji, Yang, Zhuangqing, Luo, Dan, Liu, Lihua, Chen, Junyao, Nie, Jianyun“…The Karnofsky performance status (KPS) score of the patient after 4 cycles of chemotherapy was 60 points, with severe anemia, and she could not tolerate chemotherapy. The patient was given radiotherapy to stop bleeding, and the tumor further increased in size during radiotherapy. …”
Publicado 2021
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20359“…In subgroup analysis, combination chemotherapy was associated with an improved PFS but not OS or ORR compared with TOPO alone (HR, 1.85; 95% CI, 1.52-2.24; P<0.01). The rates of G3-4 anemia, febrile neutropenia and neutropenia were similar. …”
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20360por Dabilgou, Alfred Anselme, Sondo, Apoline, Dravé, Alassane, Diallo, Ismael, Kyelem, Julie Marie Adeline, Napon, Christian, Kaboré, Jean“…Complications were significant, including local manifestations and severe anemia in 2 patients who received blood transfusion. …”
Publicado 2021
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