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21461por Qu, Ning, Chen, Lei, Liang, Shanshan, Wei, Meng, Sun, Lingshuang, He, Quan, Xue, Jinhong, Wang, Meng, Shi, Kehui, Jiang, Hongli, Liu, Hua“…A novel insight into the IBF dysfunction in CKD was provided, and it suggests a potential therapeutic use of roxadustat for the IBF dysfunction besides anemia in CKD.…”
Publicado 2022
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21462por Nabi, Aaysha T., Muttu, Jayalakshmi, Chhaparwal, Amit, Mukhopadhyay, Arka, Pattnaik, Samarjeet J., Choudhary, Pallawee“…BACKGROUND: β-Thalassemia is a chronic disease of autosomal recessive origin that is identified by the presence of a severe form of anemia. This hematological disease has been shown to directly influence a person’s physical as well as psychological well-being along with their families. …”
Publicado 2022
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21463“…BACKGROUND: Primate lentiviruses (HIV1, HIV2, and Simian immunodeficiency virus [SIV]) cause immune deficiency, encephalitis, and infectious anemia in mammals such as cattle, cat, goat, sheep, horse, and puma. …”
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21464“…They pose a high burden in pregnant women in developing countries causing maternal anemia, low birth weight, and prenatal mortality. …”
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21465por Galanis, Evanthia, Anderson, S Keith, Twohy, Erin, Butowski, Nicholas A, Hormigo, Adilia, Schiff, David, Omuro, Antonio, Jaeckle, Kurt A, Kumar, Shaji, Kaufmann, Timothy J, Geyer, Susan, Kumthekar, Priya U, Campian, Jian, Giannini, Caterina, Buckner, Jan C, Wen, Patrick Y“…An increased occurrence of grade ≥3 adverse events was seen in the combination arm, including higher incidences of anemia. Median PFS was similar in both treatment arms: 2.9 months for combination versus 3.2 months for bevacizumab monotherapy (HR = 1.16, 95% CI = 0.75–1.78, P = .51). …”
Publicado 2022
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21466por Li, Wei, Yang, Xue, Deng, Yuan, Jiang, Yina, Xu, Guiping, Li, Enxiao, Wu, Yinying, Ren, Juan, Ma, Zhenhua, Dong, Shunbin, Han, Liang, Ma, Qingyong, Wu, Zheng, Wang, Zheng“…All the patients visited dermatology first for necrolytic migratory erythema (NME) 7/7 (100%), and other presenting symptoms included diabetes mellitus (DM) 4/7 (57%), stomatitis 2/7 (28%), weight loss 4/7 (57%), anemia 4/7 (57%), diarrhea 1/7 (14%), and DVT1/7 (14%). …”
Publicado 2022
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21467por Zhong, Zhengxia, Yan, Xiaoyong, Fang, Zhengying, Dong, Yijun, Tan, Jiaxing, Xie, Jingyuan, Hu, Linhong, Zhang, Shibin, Qin, Wei“…Extrarenal features included hypertension and moderate anemia, and his parents were consanguineous (first cousins). …”
Publicado 2022
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21468por Mezzano, Julieta, Namirembe, Grace, Ausman, Lynne M., Marino-Costello, Elizabeth, Shrestha, Robin, Erhardt, Juergen, Webb, Patrick, Ghosh, Shibani“…RESULTS: After adjusting for relevant factors, we found that maternal iron status (ferritin and BIS) and anemia (hemoglobin) were not significantly associated with the assessed birth outcomes. …”
Publicado 2022
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21469por Hol, Janna A., Kuiper, Roland P., van Dijk, Freerk, Waanders, Esmé, van Peer, Sophie E., Koudijs, Marco J., Bladergroen, Reno, van Reijmersdal, Simon V., Morgado, Lionel M., Bliek, Jet, Lombardi, Maria Paola, Hopman, Saskia, Drost, Jarno, de Krijger, Ronald R., van den Heuvel-Eibrink, Marry M., Jongmans, Marjolijn C.J.“…Remaining findings included WT1-related syndromes (n = 10), Fanconi anemia (n = 1), neurofibromatosis type 1 (n = 1), and a pathogenic REST variant (n = 1). …”
Publicado 2022
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21470“…Here, we provide an extensive updated analysis of population pharmacogenomics in ten pharmacokinetic genes (CYP2D6, CYP2C19, DPYD, TPMT, NUDT15 and SLC22A1), drug targets (CFTR) and genes involved in drug hypersensitivity (HLA-A, HLA-B) or drug-induced acute hemolytic anemia (G6PD). Combined, polymorphisms in the analyzed genes affect the pharmacology, efficacy or safety of 141 different drugs and therapeutic regimens. …”
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21471“…The most common AEs of the neoadjuvant camrelizumab plus PC regimen were alopecia (51.6%), nausea and vomiting (45.2%), anemia (41.9%) and fatigue (41.9%), the majority of which occurred in patients with grade 1–2 disease. …”
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21472por Bauman, Julie E., Chen, Zhengjia, Zhang, Chao, Ohr, James P., Ferris, Robert L., McGorisk, Gerald M., Brandt, Stephen, Srivatsa, Sumathi, Chen, Amy Y., Steuer, Conor E., Shin, Dong M., Saba, Nabil F., Khuri, Fadlo R., Owonikoko, Taofeek K.“…The most frequent adverse events were anemia, stomatitis, fatigue, hyperglycemia, and hypercholesterolemia. …”
Publicado 2022
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21473por Hafizi, Redona, Imeri, Faik, Stepanovska Tanturovska, Bisera, Manaila, Roxana, Schwalm, Stephanie, Trautmann, Sandra, Wenger, Roland H., Pfeilschifter, Josef, Huwiler, Andrea“…Furthermore, these data suggest that selective inhibition of Sphk2 is an attractive new option to enhance Epo synthesis and thereby to reduce anemia development in chronic kidney disease.…”
Publicado 2022
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21474“…It has many different contributing factors, such as poor oral hygiene, smoking, anemia, bacterial plaque, poor economic status, and nutritional deficiency. …”
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21475“…Laboratory results found Normochromic Normocytic Anemia 10.4, Leukocytosis 20.200, Severe Depletion of the Immune System (404), moderate hypoalbuminemia 2.5 and moderate hyponatremia 125.9. …”
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21476“…On laboratory examination found the metabolic status Normochromic Normocytic Anemia (11,4), leukocytosis (13,600), thrombocytopenia (143,000), increased NLR (5.42), elevated transaminase enzymes (543/675), Azotemia (1,44), mild hypoalbuminemia (3,0). …”
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21477“…Laboratory findings were anemia (10.4 g/dL), leukocytosis (20,100 mm(3)), total lymphocyte count (582.9/µL), hypoalbuminemia (1.8 gr/dL), hyponatremia (132 mmol/L), elevated enzymes transaminases (SGOT 232 U/L, SGPT 88 U/L). …”
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21478por Luo, Hanqi, Cole, Chelsea, Jahan, Afrin, Peerson, Janet, Ko, Yi-An, Addo, O Yaw, Suchdev, Parminder, Young, Melissa“…METHODS: The Biomarkers Reflecting Inflammation and Nutritional Determinants of Anemia (BRINDA) project compiled 17 datasets of pregnant women (n = 14,077) from 15 countries in both high- and low-income settings. …”
Publicado 2022
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21479por Wu, Gang, Wang, Shanshan, Wang, Tingling, Han, Jiali, Yu, Anna, Feng, Changqiang, Wang, Yajing, Liu, Suzhi“…Laboratory examination revealed that all the patients did not have pernicious anemia, 4 patients had decreased vitamin B12 while 3 patients exhibited elevated homocysteine levels. …”
Publicado 2022
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21480por Giannuzzi, Giuliana, Chatron, Nicolas, Mannik, Katrin, Auwerx, Chiara, Pradervand, Sylvain, Willemin, Gilles, Hoekzema, Kendra, Nuttle, Xander, Chrast, Jacqueline, Sadler, Marie C., Porcu, Eleonora, Herault, Yann, Isidor, Bertrand, Gilbert-Dussardier, Brigitte, Eichler, Evan E., Kutalik, Zoltan, Reymond, Alexandre“…Recurrent copy-number variations (CNVs) at chromosome 16p11.2 are associated with neurodevelopmental diseases, skeletal system abnormalities, anemia, and genitourinary defects. Among the 40 protein-coding genes encompassed within the rearrangement, some have roles in leukocyte biology and immunodeficiency, like SPN and CORO1A. …”
Publicado 2022
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