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21901por Hong, Jung Yong, Yoon, Dok Hyun, Yoon, Sang Eun, Kim, Seok Jin, Lee, Ho Sup, Eom, Hyeon-Seok, Lee, Hye Won, Shin, Dong-Yeop, Koh, Youngil, Yoon, Sung-Soo, Jo, Jae-Cheol, Kim, Jin Seok, Kim, Soo-Jeong, Cho, Su-Hee, Lee, Won-Sik, Won, Jong-Ho, Kim, Won Seog, Suh, Cheolwon“…The most common grade 3/4 adverse events were thrombocytopenia (n = 13, 34.2%), neutropenia (n = 7, 23.7%), and anemia (n = 7, 18.4%). Our study showed relatively lower ORR and shorter PFS in patients with recurrent or refractory PTCLs treated with pralatrexate in real-world practice. …”
Publicado 2019
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21902por Lu, Ying, Chen, Dagui, Liang, Jinhui, Gao, Jianquan, Luo, Zhanxiong, Wang, Rensheng, Liu, Wenqi, Huang, Changjie, Ning, Xuejian, Liu, Meilian, Huang, Haixin“…During concurrent treatment with radiotherapy and chemotherapy, the NPF group showed better tolerance to radiotherapy and chemotherapy; neutropenia, anemia, gastrointestinal reactions, oral mucositis and radiation dermatitis in the NPF group were significantly reduced (P < 0.05). …”
Publicado 2019
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21903por Gholami, Yaser H, Josephson, Lee, Akam, Eman A, Caravan, Peter, Wilks, Moses Q, Pan, Xiang-Zuo, Maschmeyer, Richard, Kolnick, Aleksandra, El Fakhri, Georges, Normandin, Marc D, Kuncic, Zdenka, Yuan, Hushan“…PURPOSE: Using our chelate-free, heat-induced radiolabeling (HIR) method, we show that a wide range of metals, including those with radioactive isotopologues used for diagnostic imaging and radionuclide therapy, bind to the Feraheme (FH) nanoparticle (NP), a drug approved for the treatment of iron anemia. MATERIAL AND METHODS: FH NPs were heated (120°C) with nonradioactive metals, the resulting metal-FH NPs were characterized by inductively coupled plasma mass spectrometry (ICP-MS), dynamic light scattering (DLS), and r(1) and r(2) relaxivities obtained by nuclear magnetic relaxation spectrometry (NMRS). …”
Publicado 2020
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21904por Skoczen, Szymon, Stepien, Konrad, Mlynarski, Wojciech, Centkowski, Piotr, Kwiecinska, Kinga, Korostynski, Michal, Piechota, Marcin, Wyrobek, Elzbieta, Moryl-Bujakowska, Angelina, Strojny, Wojciech, Rej, Magdalena, Kowalczyk, Jerzy, Balwierz, Walentyna“…A 15-year-old male with NS was referred with suspicion of acute leukemia. Severe anemia, leukocytosis, thrombocytopenia, and elevated CRP level were demonstrated in pre-hospital laboratory tests. …”
Publicado 2020
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21905Publicado 2019“…Major toxicities induced by Cr (VI) were damages to small intestine and anemia in experimental animals. The finding observed at the lowest LOAEL was diffuse hyperplasia of mucosal epithelium in the duodenum in mice. …”
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21906por Katsurada, Naoko, Tachihara, Motoko, Hatakeyama, Yukihisa, Koyama, Kiyoko, Yumura, Masako, Kiriu, Tatsunori, Dokuni, Ryota, Hazama, Daisuke, Tokunaga, Shuntaro, Tamura, Daisuke, Nakata, Kyosuke, Yamamoto, Masatsugu, Kamiryo, Hiroshi, Kobayashi, Kazuyuki, Tanaka, Yugo, Maniwa, Yoshimasa, Nishimura, Yoshihiro“…The most common grade 3 or 4 adverse events were neutropenia (n=15, 78.9%) and anemia (n=3, 15.8%). The completion rate for the four cycles was 63.2% (95% CI, 38.4–83.7). …”
Publicado 2020
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21907por Salam, Rehana A, Das, Jai K, Ahmed, Wardah, Irfan, Omar, Sheikh, Sana Sadiq, Bhutta, Zulfiqar A“…Among primary outcomes, we are uncertain of the effect of iron supplementation with or without folic acid on anemia (daily supplementation; relative risk (RR): 1.04, 95% confidence interval (CI) 0.42, 2.57; one study; 1160 participants; low-quality evidence; weekly supplementation; RR: 1.07, 95% CI: 0.46, 2.52; one study; 1247 participants; low-quality evidence). …”
Publicado 2019
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21908por Wang, Yudong, Janku, Filip, Piha-Paul, Sarina, Hess, Kenneth, Broaddus, Russell, Liu, Lidong, Shi, Naiyi, Overman, Michael, Kopetz, Scott, Subbiah, Vivek, Naing, Aung, Hong, David, Tsimberidou, Apostolia M., Karp, Daniel, Yao, James, Fu, Siqing“…Common treatment-related adverse events in NCT02042989 included anemia, thrombocytopenia, fatigue, nausea, vomiting, and diarrhea. …”
Publicado 2020
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21909por Scrutinio, Domenico, Battista, Petronilla, Guida, Pietro, Lanzillo, Bernardo, Tortelli, Rosanna“…Comorbidity, including diabetes, anemia, coronary artery disease, atrial fibrillation, and chronic obstructive pulmonary disease, significantly increased mortality risk by 49–88%. …”
Publicado 2020
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21910“…RESULTS: We found that greater age (AOR = 1.02, 95% CI: 1.01,1.05), fair or poor adherence (AOR = 2.77, 95% CI: 1.40, 5.50 and AOR = 4.72, 95% CI: 1.92, 11.6), and the presence of OIs (AOR = 1.70, 95% CI: 1.12, 2.52), anemia (AOR = 1.81, 95% CI: 1.07, 3.07), or eating problems (AOR = 3.40, 95% CI: 2.27, 5.10), were all independently and positively associated with under nutrition. …”
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21911por Lei, Pu-Run, Liao, Jing-Wen, Ruan, Ying, Yang, Xiao-Feng, Hu, Kun-Peng, Liu, Jian-Pei, Chen, Tu-Feng“…RESULTS: Univariate analysis of the baseline characteristics revealed that younger age (odds ratio [OR]: 0.378; 95% confidence interval [CI]: 0.218–0.657) and pre-operative oral antibiotic use (OR: 0.465; 95% CI: 0.255–0.850) were protective factors, while pre-operative anemia (OR: 4.591; 95% CI: 2.567–8.211), neoadjuvant chemotherapy history (OR: 2.398; 95% CI: 1.094–5.256), and longer surgical duration (OR: 2.393; 95% CI: 1.349–4.246; P = 0.002) were identified as risk factors for SSI. …”
Publicado 2020
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21912por Feng, Fanchao, Huang, Jingyi, Wang, Zhichao, Zhang, Jiarui, Han, Di, Wu, Qi, He, Hailang, Zhou, Xianmei“…The meta-analysis showed that XAPI adjunctive to platinum-based chemotherapy had better outcomes in objective tumor response rate (ORR) (RR: 1.27, 95% CI, 1.14–1.40); improved Karnofsky performance scores (KPS) (RR: 1.70, 95% CI, 1.48–1.95); reduction in occurrence of grade 3/4 leukopenia (RR: 0.49, 95% CI, 0.38–0.64), anemia (RR: 0.63, 95% CI, 0.46–0.87) and thrombocytopenia (RR: 0.53, 95% CI, 0.38–0.73), nausea and vomiting (RR: 0.57, 95% CI, 0.36–0.90); and enhanced immune function (CD8(+) [MD: 4.96, 95% CI, 1.16–8.76] and CD4(+)/CD8(+) [MD: 2.58, 95% CI, 1.69–3.47]). …”
Publicado 2020
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21913por Kishikawa, Takayuki, Kasai, Takashi, Okada, Masahiko, Nakachi, Ichiro, Soda, Sayo, Arai, Ryo, Takigami, Ayako, Sata, Masafumi“…Adverse events of grade ≥ 3 were reported in 15 patients (26.8%); the most common were anemia (n = 3) and cutaneous toxicity (n = 3). Grade 4 neutropenia was observed in one patient; any‐grade pneumonitis was observed in six patients (10.7%), including one with grade 3 pneumonitis. …”
Publicado 2020
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21914por González-Fernández, Doris, Pons, Emérita del Carmen, Rueda, Delfina, Sinisterra, Odalis Teresa, Murillo, Enrique, Scott, Marilyn E., Koski, Kristine G.“…Methods: Environmental and dietary factors, intake of iron and a multiple-nutrient supplement (MNS), markers of inflammation, protein, anemia, folate, vitamins B(12), A and D status, and urogenital, skin, oral and intestinal nematode infections were measured in indigenous pregnant Panamanian women. …”
Publicado 2020
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21915por Lara, Luis F., Silva, Rogelio, Thakkar, Shyam, Stanich, Peter P., Mai, Daniel, Samarasena, Jason B.“…METHODS: Patients with a previous diagnosis of small-bowel angiodysplasia (SBA) and ongoing bleeding with melena, hematochezia, or iron-deficiency anemia were eligible for treatment. A small-bowel radiofrequency ablation (SBRFA) catheter was passed through the enteroscope instrument channel. …”
Publicado 2020
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21916por Gedefaw, Getnet, Demis, Asmamaw, Alemnew, Birhan, Wondmieneh, Adam, Getie, Addisu, Waltengus, Fikadu“…The common neonatal complications following Caesarean section included low APGAR score, perinatal asphyxia, neonatal sepsis, meconium aspiration syndrome, early neonatal death, stillbirth, and prematurity whereas febrile morbidity, surgical site infection, maternal mortality, severe anemia, and postpartum hemorrhage were the most common maternal complications following Caesarean section. …”
Publicado 2020
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21917por Alebel, Animut, Kibret, Getiye Dejenu, Petrucka, Pammla, Tesema, Cheru, Moges, Nurilign Abebe, Wagnew, Fasil, Asmare, Getnet, Kumera, Gemechu, Bitew, Zebenay Workneh, Ketema, Daniel Bekele, Tiruneh, Tesfahun, Melkamu, Mamaru Wubale, Hibstie, Yitbarek Tenaw, Temesgen, Belisty, Eshetie, Setegn“…This study also revealed that undernutrition is more common among HIV-positive adults with advanced disease stage, anemia, diarrhea, CD4 count less than 200 cells/mm(3), and living in rural areas. …”
Publicado 2020
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21918“…Furthermore, hypertension was found to be the most common comorbidity among patients (87.2%, n = 129), followed by anemia (48.6%, n = 72), diabetes (47.3%, n = 70), dyslipidemia (19.6%, n = 29), and peptic ulcer (19.6%, n = 29). …”
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21919por Piha-Paul, Sarina A, Hann, Christine L, French, Christopher A, Cousin, Sophie, Braña, Irene, Cassier, Phillippe A, Moreno, Victor, de Bono, Johann S, Harward, Sara Duckworth, Ferron-Brady, Geraldine, Barbash, Olena, Wyce, Anastasia, Wu, Yuehui, Horner, Thierry, Annan, Meg, Parr, Nigel J, Prinjha, Rabinder K, Carpenter, Christopher L, Hilton, John, Hong, David S, Haas, Naomi B, Markowski, Mark C, Dhar, Arindam, O’Dwyer, Peter J, Shapiro, Geoffrey I“…The most frequent treatment-related adverse events of any grade were thrombocytopenia (51%) and gastrointestinal events, including nausea, vomiting, diarrhea, decreased appetite, and dysgeusia (22%–42%), anemia (22%), and fatigue (20%). Molibresib demonstrated an acceptable safety profile up to 100 mg; 80 mg once daily was selected as the recommended phase II dose. …”
Publicado 2019
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21920por Yamaya, Mutsuo, Usami, Osamu, Nakayama, Shoichi, Tode, Naoki, Yamada, Aya, Ito, Shunsuke, Omata, Fumiya, Momma, Haruki, Funakubo, Masakatsu, Ichinose, Masakazu“…In the univariate analysis, the risk factors for exacerbation were age; long-term oxygen therapy; low FVC, FEV(1), FEV(1)/FVC and %FEV(1); high COPD severity ranking and mMRC score; severe emphysema; hypoproteinemia (<6.5 g/dL); hypoalbuminemia (<3.5 g/dL); leukocytosis; lymphocytopenia; and anemia. In the multivariate analysis, the risk factors were hypoalbuminemia, hypoproteinemia and low FEV(1). …”
Publicado 2020
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