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  1. 23061
    “…While the reasons are unknown and require validation in large cohorts, the symptoms of leukemia including symptomatic anemia (low hematocrit) and higher WBC and blast count possibly driven by FLT3 mutations may drive patients to seek emergent clinical evaluation despite COVID pandemic barriers. …”
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  2. 23062
    por Kassebaum, Nicholas, Kyu, Hmwe Hmwe, Zoeckler, Leo, Olsen, Helen Elizabeth, Thomas, Katie, Pinho, Christine, Bhutta, Zulfiqar A., Dandona, Lalit, Ferrari, Alize, Ghiwot, Tsegaye Tewelde, Hay, Simon I., Kinfu, Yohannes, Liang, Xiaofeng, Lopez, Alan, Malta, Deborah Carvalho, Mokdad, Ali H., Naghavi, Mohsen, Patton, George C., Salomon, Joshua, Sartorius, Benn, Topor-Madry, Roman, Vollset, Stein Emil, Werdecker, Andrea, Whiteford, Harvey A., Abate, Kalkidan Hasen, Abbas, Kaja, Damtew, Solomon Abrha, Ahmed, Muktar Beshir, Akseer, Nadia, Al-Raddadi, Rajaa, Alemayohu, Mulubirhan Assefa, Altirkawi, Khalid, Abajobir, Amanuel Alemu, Amare, Azmeraw T., Antonio, Carl A. T., Arnlov, Johan, Artaman, Al, Asayesh, Hamid, Avokpaho, Euripide Frinel G. Arthur, Awasthi, Ashish, Ayala Quintanilla, Beatriz Paulina, Bacha, Umar, Betsu, Balem Demtsu, Barac, Aleksandra, Bärnighausen, Till Winfried, Baye, Estifanos, Bedi, Neeraj, Bensenor, Isabela M., Berhane, Adugnaw, Bernabe, Eduardo, Bernal, Oscar Alberto, Beyene, Addisu Shunu, Biadgilign, Sibhatu, Bikbov, Boris, Boyce, Cheryl Anne, Brazinova, Alexandra, Hailu, Gessessew Bugssa, Carter, Austin, Castañeda-Orjuela, Carlos A., Catalá-López, Ferrán, Charlson, Fiona J., Chitheer, Abdulaal A., Choi, Jee-Young Jasmine, Ciobanu, Liliana G., Crump, John, Dandona, Rakhi, Dellavalle, Robert P., Deribew, Amare, deVeber, Gabrielle, Dicker, Daniel, Ding, Eric L., Dubey, Manisha, Endries, Amanuel Yesuf, Erskine, Holly E., Faraon, Emerito Jose Aquino, Faro, Andre, Farzadfar, Farshad, Fernandes, Joao C., Fijabi, Daniel Obadare, Fitzmaurice, Christina, Fleming, Thomas D., Flor, Luisa Sorio, Foreman, Kyle J., Franklin, Richard C., Fraser, Maya S., Frostad, Joseph J., Fullman, Nancy, Gebregergs, Gebremedhin Berhe, Gebru, Alemseged Aregay, Geleijnse, Johanna M., Gibney, Katherine B., Gidey Yihdego, Mahari, Ginawi, Ibrahim Abdelmageem Mohamed, Gishu, Melkamu Dedefo, Gizachew, Tessema Assefa, Glaser, Elizabeth, Gold, Audra L., Goldberg, Ellen, Gona, Philimon, Goto, Atsushi, Gugnani, Harish Chander, Jiang, Guohong, Gupta, Rajeev, Tesfay, Fisaha Haile, Hankey, Graeme J., Havmoeller, Rasmus, Hijar, Martha, Horino, Masako, Hosgood, H. Dean, Hu, Guoqing, Jacobsen, Kathryn H., Jakovljevic, Mihajlo B., Jayaraman, Sudha P., Jha, Vivekanand, Jibat, Tariku, Johnson, Catherine O., Jonas, Jost, Kasaeian, Amir, Kawakami, Norito, Keiyoro, Peter N., Khalil, Ibrahim, Khang, Young-Ho, Khubchandani, Jagdish, Ahmad Kiadaliri, Aliasghar A., Kieling, Christian, Kim, Daniel, Kissoon, Niranjan, Knibbs, Luke D., Koyanagi, Ai, Krohn, Kristopher J., Kuate Defo, Barthelemy, Kucuk Bicer, Burcu, Kulikoff, Rachel, Kumar, G. Anil, Lal, Dharmesh Kumar, Lam, Hilton Y., Larson, Heidi J., Larsson, Anders, Laryea, Dennis Odai, Leung, Janni, Lim, Stephen S., Lo, Loon-Tzian, Lo, Warren D., Looker, Katharine J., Lotufo, Paulo A., Magdy Abd El Razek, Hassan, Malekzadeh, Reza, Markos Shifti, Desalegn, Mazidi, Mohsen, Meaney, Peter A., Meles, Kidanu Gebremariam, Memiah, Peter, Mendoza, Walter, Abera Mengistie, Mubarek, Mengistu, Gebremichael Welday, Mensah, George A., Miller, Ted R., Mock, Charles, Mohammadi, Alireza, Mohammed, Shafiu, Monasta, Lorenzo, Mueller, Ulrich, Nagata, Chie, Naheed, Aliya, Nguyen, Grant, Nguyen, Quyen Le, Nsoesie, Elaine, Oh, In-Hwan, Okoro, Anselm, Olusanya, Jacob Olusegun, Olusanya, Bolajoko O., Ortiz, Alberto, Paudel, Deepak, Pereira, David M., Perico, Norberto, Petzold, Max, Phillips, Michael Robert, Polanczyk, Guilherme V., Pourmalek, Farshad, Qorbani, Mostafa, Rafay, Anwar, Rahimi-Movaghar, Vafa, Rahman, Mahfuzar, Rai, Rajesh Kumar, Ram, Usha, Rankin, Zane, Remuzzi, Giuseppe, Renzaho, Andre M. N., Roba, Hirbo Shore, Rojas-Rueda, David, Ronfani, Luca, Sagar, Rajesh, Sanabria, Juan Ramon, Kedir Mohammed, Muktar Sano, Santos, Itamar S., Satpathy, Maheswar, Sawhney, Monika, Schöttker, Ben, Schwebel, David C., Scott, James G., Sepanlou, Sadaf G., Shaheen, Amira, Shaikh, Masood Ali, She, June, Shiri, Rahman, Shiue, Ivy, Sigfusdottir, Inga Dora, Singh, Jasvinder, Silpakit, Naris, Smith, Alison, Sreeramareddy, Chandrashekhar, Stanaway, Jeffrey D., Stein, Dan J., Steiner, Caitlyn, Sufiyan, Muawiyyah Babale, Swaminathan, Soumya, Tabarés-Seisdedos, Rafael, Tabb, Karen M., Tadese, Fentaw, Tavakkoli, Mohammad, Taye, Bineyam, Teeple, Stephanie, Tegegne, Teketo Kassaw, Temam Shifa, Girma, Terkawi, Abdullah Sulieman, Thomas, Bernadette, Thomson, Alan J., Tobe-Gai, Ruoyan, Tonelli, Marcello, Tran, Bach Xuan, Troeger, Christopher, Ukwaja, Kingsley N., Uthman, Olalekan, Vasankari, Tommi, Venketasubramanian, Narayanaswamy, Vlassov, Vasiliy Victorovich, Weiderpass, Elisabete, Weintraub, Robert, Gebrehiwot, Solomon Weldemariam, Westerman, Ronny, Williams, Hywel C., Wolfe, Charles D. A., Woodbrook, Rachel, Yano, Yuichiro, Yonemoto, Naohiro, Yoon, Seok-Jun, Younis, Mustafa Z., Yu, Chuanhua, Zaki, Maysaa El Sayed, Zegeye, Elias Asfaw, Zuhlke, Liesl Joanna, Murray, Christopher J. L., Vos, Theo
    Publicado 2017
    “…Other than infectious conditions, many top causes of disability are associated with long-term sequelae of conditions present at birth (eg, neonatal disorders, congenital birth defects, and hemoglobinopathies) and complications of a variety of infections and nutritional deficiencies. Anemia, developmental intellectual disability, hearing loss, epilepsy, and vision loss are important contributors to childhood disability that can arise from multiple causes. …”
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  3. 23063
  4. 23064
  5. 23065
  6. 23066
    por Tan, IB, Chang, Ellen T., Chen, Chien-Jen, Hsu, Wan-Lun, Chien, Yin-Chu, Hildesheim, Allan, McKay, James D., Gaborieau, Valerie, Kaderi, Mohamed Arifin Bin, Purnomosari, Dewajani, Voegele, Catherine, LeCalvez-Kelm, Florence, Byrnes, Graham, Brennan, Paul, Devi, Beena, Li, L., Zhang, Y., Fan, Y., Sun, K., Du, Z., Sun, H., Chan, A. T., Tsao, S. W., Zeng, Y. X., Tao, Q., Busson, Pierre, Lhuillier, Claire, Morales, Olivier, Mrizak, Dhafer, Gelin, Aurore, Kapetanakis, Nikiforos, Delhem, Nadira, Mansouri, Sheila, Cao, Jennifer, Vaidya, Anup, Frappier, Lori, Wai, Lo Kwok, Chen, Sui-Hong, Du, Jin-lin, Ji, Ming-Fang, Huang, Qi-Hong, Liu, Qing, Cao, Su-Mei, Doolan, Denise L., Coghill, Anna, Mulvenna, Jason, Proietti, Carla, Lekieffre, Lea, Bethony, Jeffrey, Hildesheim, and Allan, Fles, Renske, Indrasari, Sagung Rai, Herdini, Camelia, Martini, Santi, Isfandiari, Atoillah, Rhomdoni, Achmad, Adham, Marlinda, Mayangsari, Ika, van Werkhoven, Erik, Wildeman, Maarten, Hariwiyanto, Bambang, Hermani, Bambang, Kentjono, Widodo Ario, Haryana, Sofia Mubarika, Schmidt, Marjanka, Tan, IB, O’Sullivan, Brian, Ozyar, Enis, Lee, Anne W. M., Zeng, Mu-Sheng, Gao, Xiaojiang, Tang, Minzhong, Martin, Pat, Zeng, Yi, Carrington, Mary, Coghill, Anna E., Bu, Wei, Nguyen, Hanh, Hsu, Wan-Lun, Yu, Kelly J., Lou, Pei-Jen, Wang, Cheng-Ping, Chen, Chien-Jen, Hildesheim, Allan, Cohen, Jeffrey I., King, Ann D., Chien, Yin-Chu, Hsu, Wan-Lun, Yu, Kelly J., Chen, Tseng-Cheng, Lin, Ching-Yuan, Tsou, Yung-An, Leu, Yi-Shing, Laio, Li-Jen, Chang, Yen-Liang, Wang, Cheng-Ping, Hua, Chun-Hun, Wu, Ming-Shiang, Hsiao, Chu-Hsing Kate, Lee, Jehn-Chuan, Tsai, Ming-Hsui, Cheng, Skye Hung-Chun, Lou, Pei-Jen, Hildesheim, Allan, Chen, Chien-Jen, Hsu, Wan-Lun, Yu, Kelly J., Chien, Yin-Chu, Chen, Tseng-Cheng, Lin, Ching-Yuan, Tsou, Yung-An, Leu, Yi-Shing, Liao, Li-Jen, Chang, Yen-Liang, Yang, Tsung-Lin, Hua, Chun-Hun, Wu, Ming-Shiang, Hsiao, Chu-Hsing Kate, Lee, Jehn-Chuan, Tsai, Ming-Hsui, Cheng, Skye Hung-Chun, Ko, Jenq-Yuh, Hildesheim, Allan, Chen, Chien-Jen, Ko, Josephine Mun Yee, Dai, Wei, Kwong, Dora, Ng, Wai Tong, Lee, Anne, Ngan, Roger Kai Cheong, Yau, Chun Chung, Tung, Stewart, Lung, Maria Li, Ji, Mingfang, Sheng, Wei, Ng, Mun Hon, Cheng, Weimin, Yu, Xia, Wu, Biaohua, Wei, Kuangrong, Zhan, Jun, Zeng, Yi Xin, Cao, Su Mei, Xia, Ningshao, Yuan, Yong, Cui, Qian, Xu, Miao, Bei, Jin-Xin, Zeng, Yi-Xin, Şahin, B, Dizman, A, Esassolak, M, İkizler, A Saran, Yıldırım, HC, Çaloğlu, M, Atalar, B, Akman, F, Demiroz, C, Atasoy, BM, Canyilmaz, E, Igdem, S, Ugurluer, G, Kütük, T, Akmansoy, M, Ozyar, E, Sommat, Kiattisa, Wang, Fu Qiang, Kwok, Li-Lian, Tan, Terence, Fong, Kam Weng, Soong, Yoke Lim, Cheah, Shie Lee, Wee, Joseph, Casanova, M, Özyar, E, Patte, C, Orbach, D, Ferrari, A, Cristine, VF, Errihani, H, Pan, J, Zhang, L, Liji, S, Grzegorzewski, K, Gore, L, Varan, A, Hutajulu, Susanna Hilda, Khuzairi, Guntara, Herdini, Camelia, Kusumo, Henry, Hardianti, Mardiah Suci, Taroeno-Hariadi, Kartika Widayati, Purwanto, Ibnu, Kurnianda, Johan, Messick, Troy E., Malecka, Kimberly, Tolvinski, Lois, Soldan, Samantha, Deakyne, Julianna, Song, Hui, van den Heuvel, Antonio, Gu, Baiwei, Cassel, Joel, McDonnell, Mark, Smith, Garry R., Velvadapu, Venkata, Bian, Haiyan, Zhang, Yan, Carlsen, Marianne, Chen, Shuai, Donald, Alastair, Lemmen, Christian, Reitz, Allen B., Lieberman, Paul M., Chan, King Chi, Chan, Lai Sheung, Lo, Kwok Wai, Yip, Timothy Tak Chun, Ngan, Roger Kai Cheong, Kahn, Michael, Lung, Maria Li, Mak, Nai Ki, Liu, Fei-Fei, Khaali, Wafa, Thariat, Juliette, Fantin, Laurence, Spirito, Flavia, Khyatti, Meriem, Driss, El Khalil Ben, Olivero, Sylvain, Maryanski, Janet, Doglio, Alain, Xia, Mengxue, Xia, Yunfei, Chang, Hui, Shaw, Rachel, Rahaju, Pudji, Hardianti, Mardiah Suci, Wisesa, Sindhu, Taroeno-Harijadi, Kartika Widayati, Purwanto, Ibnu, Hariwiyanto, Bambang, Dhamiyati, Wigati, Kurnianda, Johan, Tan, Sang-Nee, Sim, Sai-Peng, Yusuf, Muhtarum, Romdhoni, Ahmad C., K, Widodo Ario, Rantam, Fedik Abdul, Sugiyanto, Aryati, Lina, Adi-Kusumo, Fajar, Hardianti, Mardiah Suci, Bintoro, SY, Oktriani, R., Herawati, C., Surono, A., Haryana, Sofia M., Zhong, L., Li, L., Ma, B. B., Chan, A. T., Tao, Q., Kalra, M., Ngo, M., Perna, S., Leen, A., Lapteva, N., Rooney, C. M., Gottschalk, S., Mustikaningtyas, Elida, Herawati, Sri, Romdhoni, Achmad C., Ji, Mingfang, Xu, Yarui, Cheng, Weimin, Ge, Shengxiang, Li, Fugui, Ng, M. H., Tan, Louise SY, Wong, Benjamin, Lim, C. M., Romdhoni, Achmad C., Rantam, Fedik A., Kentjono, Widodo Ario, Madani, Deasy Z., Akbar, Nur, Permana, Agung Dinasti, Herdini, Camelia, Indrasari, Sagung Rai, Fachiroh, Jajah, Hartati, Dwi, Rahayudjati, T. Baning, Darwis, Iswandi, Hutajulu, Susanna Hilda, Hariwiyanto, Bambang, Dhamiyati, Wigati, Purwanto, Ibnu, Taroeno-Hariadi, Kartika Widayati, Kurnianda, Johan, Wisesa, Sindhu, Hardianti, Mardiah Suci, Hutajulu, Susanna Hilda, Taroeno-Harijadi, Kartika Widayati, Purwanto, Ibnu, Herdini, Camelia, Dhamiyati, Wigati, Kurnianda, Johan, Anwar, Khoirul, Hutajulu, Susanna Hilda, Indrasari, Sagung Rai, Dwidanarti, Sri Retna, Purwanto, Ibnu, Taroeno-Hariadi, Kartika Widayati, Kurnianda, Johan, Pramana, Dominicus Wendhy, Hutajulu, Susanna Hilda, Hariwiyanto, Bambang, Dhamiyati, Wigati, Purwanto, Ibnu, Taroeno-Hariadi, Kartika Widayati, Kurnianda, Johan, Safitri, Diah Ari, Hutajulu, Susanna Hilda, Herdini, Camelia, Danarti, Sri Retna Dwi, Purwanto, Ibnu, Taroeno-Hariadi, Kartika Widayati, Kurnianda, Johan, Taroeno, Suryo A, Wisesa, Sindhu, Taroeno-Hariadi, Kartika Widayati, Purwanto, Ibnu, Hariwiyanto, Bambang, Dhamiyati, Wigati, Kurnianda, Johan, Wijaya, I., Oehadian, A., Prasetya, D., Hsu, Wan-Lun, Chien, Yin-Chu, Yu, Kelly J, Wang, Cheng-Ping, Lin, Ching-Yuan, Tsou, Yung-An, Leu, Yi-Shing, Liao, Li-Jen, Chang, Yen-Liang, Ko, Jenq-Yuh, Hua, Chun-Hun, Wu, Ming-Shiang, Hsiao, Chu-Hsing Kate, Lee, Jehn-Chuan, Tsai, Ming-Hsui, Cheng, Skye Hung-Chun, Lou, Pei-Jen, Hildesheim, Allan, Chen, Chien-Jen, Rahman, Sukri, Budiman, Bestari J., Novialdi, Rahmadona, Lestari, Dewi Yuri, Yin, C., Foussadier, A., Blein, E., Chen, C., Ammour, N. Bournet, Khiatti, M., Cao, S., Marzaini, Dewi Syafriyetti Soeis, Hartati, Dwi, Rahayujati, Baning, Herdini, Camelia, Fachiroh, Jajah, Gunawan, L., Mubarika Haryana, S., Surono, A., Herawati, C., Hartono, Michael, Fachiroh, Jajah, Intansari, Umi, Paramita, Dewi Kartikawati, Akbar, Akmal, Fachiroh, Jajah, Paramita, Dewi Kartikawati, Hermawan, Benny, Rahayudjati, T. Baning, Paramita, Dewi K., Fachiroh, Jajah, Argy, Gabriella, Fachiroh, Jajah, Paramita, Dewi Kartikawati, Hutajulu, Susanna Hilda, Sihotang, Theodora Caroline, Fachiroh, Jajah, Intansari, Umi, Paramita, Dewi Kartikawati, Wahyono, Daniel Joko, Soeharso, Purnomo, Suryandari, Dwi Anita, Lisnawati, Musa, Zanil, Hermani, Bambang, Daker, Maelinda, Tzen, Yeo Jiun, Bakar, Norhasimah, Rahman, Asma’ Saiyidatina Aishah Abdul, Ahmad, Munirah, Chia, Yeo Tiong, Beng, Alan Khoo Soo, Sasikirana, Widyandani, Wardana, Tirta, Radifar, Muhammad, Herawati, Cita, Surono, Agus, Haryana, Sofia Mubarika
    Publicado 2016
    “…Baning Rahayudjati P3 Report on loco regionally advanced nasopharyngeal cancer patients treated with induction chemotherapy followed by concurrent chemo-radiation therapy Iswandi Darwis, Susanna Hilda Hutajulu, Bambang Hariwiyanto, Wigati Dhamiyati, Ibnu Purwanto, Kartika Widayati Taroeno-Hariadi, Johan Kurnianda P4 Sex and age differences in the survival of patients with nasopharyngeal carcinoma Sindhu Wisesa, Mardiah Suci Hardianti, Susanna Hilda Hutajulu, Kartika Widayati Taroeno-Harijadi, Ibnu Purwanto, Camelia Herdini, Wigati Dhamiyati, Johan Kurnianda P5 Impact of delayed diagnosis and delayed therapy in the treatment outcome of patients with nasopharyngeal carcinoma Khoirul Anwar, Susanna Hilda Hutajulu, Sagung Rai Indrasari, Sri Retna Dwidanarti, Ibnu Purwanto, Kartika Widayati Taroeno-Hariadi, Johan Kurnianda P6 Anaysis of pretreatment anemia in nasopharyngeal cancer patients undergoing neoadjuvant therapy Dominicus Wendhy Pramana, Susanna Hilda Hutajulu, Bambang Hariwiyanto, Wigati Dhamiyati, Ibnu Purwanto, Kartika Widayati Taroeno-Hariadi, Johan Kurnianda P7 Results of treatment with neoadjuvant cisplatin-5FU in locally advanced nasopharyngeal carcinoma: a local experience Diah Ari Safitri, Susanna Hilda Hutajulu, Camelia Herdini, Sri Retna Dwi Danarti, Ibnu Purwanto, Kartika Widayati Taroeno-Hariadi, Johan Kurnianda P8 Geriatrics with nasopharyngeal cancer Suryo A Taroeno, Sindhu Wisesa, Kartika Widayati Taroeno-Hariadi, Ibnu Purwanto, Bambang Hariwiyanto, Wigati Dhamiyati, Johan Kurnianda P9 Correlation of lymphocyte to monocyte and neutrophil to lymphocyte ratio to the response of cisplatin chemoradiotheraphy in locally advance nasopharyngeal carcinoma I. …”
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  7. 23067
    “…Defects in erythropoiesis can lead to blood disorders such as congenital dyserythropoietic anemias, Diamond–Blackfan anemias, sideroblastic anemias, myelodysplastic syndrome, and porphyria. …”
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  8. 23068
    “…Children with thalassemia, adults with myelodysplastic syndromes, and patients with autoimmune hemolytic anemias, leukemias, or aplastic anemias become chronically dependent on blood transfusions. …”
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  9. 23069
    por Tanno, Toshihiko, Miller, Jeffery L.
    Publicado 2010
    “…Thus, iron usage for the hemoglobin production is a primary regulator of plasma iron supply and demand. In many anemias, additional sources of iron from diet and tissue stores are needed to meet the erythroid demand. …”
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  10. 23070
    “…Disorders of normal heme synthesis may cause human diseases, including certain anemias (X-linked sideroblastic anemias) and porphyrias. …”
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  11. 23071
    “…BACKGROUND: Compliance, palatability, gastrointestinal (GI) symptom, and treatment satisfaction patient- and observer-reported outcome (PRO, ObsRO) measures were developed/modified for patients with transfusion-dependent anemias or myelodysplastic syndrome (MDS) requiring iron chelation therapy (ICT). …”
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  12. 23072
    “…Hematologic improvement (HI) occurs in some patients with acquired anemias and transfusional iron overload receiving iron chelation therapy (ICT) but there is little information on transfusion status after stopping chelation. …”
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  13. 23073
    por Thomas, Emy Abi, Kadyan, R S
    Publicado 2008
    “…Alopecia areata (AA) frequently occur in association with other autoimmune diseases such as thyroid disorders, anemias and other skin disorders with autoimmune etiology. …”
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  14. 23074
    “…MATERIALS AND METHODS: A retrospective descriptive study was carried out analizing death certificates from 2014 to 2016, whose basic cause of death was nutritional deficiencies and anemias. Mortality rates were estimated by sex and department of residence, and distribution frequencies were built based on demographic variables. …”
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  15. 23075
    “…SARS-CoV2 can also induce or exacerbate immune-mediated cytopenias, such as autoimmune hemolytic anemias, complement-mediated anemias, and immune thrombocytopenia. …”
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  16. 23076
    “…BACKGROUND: Microangiopathic hemolytic anemias and thrombocytopenias in pregnant or postpartum women constitute an interdisciplinary diagnostic and therapeutic challenge in the evaluation of thrombotic microangiopathies (TMA), where urgent care must be considered. …”
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  17. 23077
    Publicado 1985
    “…However, unlike other genetically caused anemias, there was no reduction in the number of germ cells. …”
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  18. 23078
    “…In congenital sideroblastic anemias, instead, an altered utilization of mitochondrial iron by erythroid precursors leads to mitochondrial iron overload and an accumulation of ring sideroblasts in the bone marrow. …”
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  19. 23079
    por Wright, A., Hawkins, W. B.
    Publicado 1938
    “…In the periods of blood regeneration following such acute anemias there are no significant alterations in the values for plasma or bile cholesterol.…”
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  20. 23080
    “…This was caused by ferumoxytol, which is used to treat some anemias. Such nongadolinium-based therapeutics exhibiting unintended MRI contrast-like properties preclude assessment of enhancement kinetics in breast MRI significantly limiting diagnostic interpretation. …”
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