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19941por Levin, Carina, Koren, Ariel, Rebibo-Sabbah, Annie, Koifman, Naama, Brenner, Benjamin, Aharon, Anat“…RBC-EV levels correlated with patient hematocrit, reflecting degree of anemia. The procoagulant potential of the EVs evaluated by flow cytometry revealed lower levels of endothelial protein C receptor-labeled EVs in patients vs. controls, and increased tissue factor-to-tissue factor pathway inhibitor-labeled EV ratio in splenectomized patients, suggesting a hypercoagulable state. …”
Publicado 2018
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19942por Starnes, Joseph R., Chamberlain, Liz, Sutermaster, Staci, Owuor, Mercy, Okoth, Vincent, Edman, William, Moon, Troy D.“…The most common causes of death among children under five were malaria (19%), respiratory infection (13%), and anemia (11%). The under-five mortality rate was 104.8 per 1,000 live births from 1999 to 2006 and 53.0 per 1,000 after the founding of the Lwala Community Alliance in 2007. …”
Publicado 2018
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19943por Bouché, Olivier, Cesne, Axel Le, Rios, Maria, Chaigneau, Loic, Italiano, Antoine, Duffaud, Florence, Lecomte, Thierry, Arsène, Dominique, Manfredi, Sylvain, Aparicio, Thomas, Remy, Stéphane, Isambert, Nicolas, Collard, Olivier, Priou, Frank, Bertucci, François, Sambuc, Roland, Bisot-Locard, Ségolene, Bourges, Olivier, Chabaud, Sylvie, Blay, Jean-Yves“…The most common adverse events (AEs) were diarrhea (39%), asthenia (39%), eyelid or periorbital edema (32%), abdominal pain (23%), and anemia (21%). Eight of 126 serious AEs were possibly related to the treatment as assessed by investigators. …”
Publicado 2018
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19944por Nyström, Kristina, Wanrooij, Paulina H., Waldenström, Jesper, Adamek, Ludmila, Brunet, Sofia, Said, Joanna, Nilsson, Staffan, Wind-Rotolo, Megan, Hellstrand, Kristoffer, Norder, Helene, Tang, Ka-Wei, Lagging, Martin“…Reduced ITPase activity was earlier reported to protect against ribavirin-induced hemolytic anemia and to diminish relapse following ribavirin and interferon therapy for hepatitis C virus (HCV) genotype 2 or 3 infections. …”
Publicado 2018
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19945por Vera Aguilera, Jesus, Rao, Ravi D., Allred, Jacob B., Suman, Vera J., Windschitl, Harold E., Kaur, Judith S., Maples, William J., Lowe, Val J., Creagan, Edward T., Erickson, Lori A., Markovic, Svetomir“…Dose‐limiting toxicities included grade 4 myocardial ischemia (3.4%); grade 3 fatigue, mucositis, and hyperglycemia (10.3%); and anorexia and anemia (6.9%). Everolimus significantly reduced the number of Tregs in approximately half of the treated patients; however, these effects were not correlated with clinical outcomes. …”
Publicado 2018
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19946por Tomori, Yuji, Motoda, Norio, Ohashi, Ryuji, Sawaizumi, Takuya, Nanno, Mitsuhiko, Takai, Shinro“…In previously reported cases, patients have had a history of steroid use for systemic illness such as autoimmune hemolytic anemia, systemic lupus erythematosus, or renal transplantation, or have had other risk factors, such as smoking, alcoholism, or infection. …”
Publicado 2018
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19947por Vries, Minka J., van der Meijden, Paola E., Kuiper, Gerhardus J., Nelemans, Patricia J., Wetzels, Rick J., van Oerle, René G., Lancé, Marcus D., ten Cate, Hugo, Henskens, Yvonne M.“…Patients with known bleeding disorders, antithrombotic drugs, thrombocytopenia, and anemia were excluded. Preoperatively, all patients underwent elaborate hemostatic testing. …”
Publicado 2018
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19948por Penda, Calixte Ida, Moukoko, Else Carole Eboumbou, Nolla, Nicolas Policarpe, Evindi, Nadia Olivia Abomo, Ndombo, Paul Koki“…The overall prevalence of anemia, oropharyngeal candidiasis and pulmonary tuberculosis were 34.6%, 12% and 8.8%, respectively. …”
Publicado 2018
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19949“…In addition, patients treated with VEGF or VEGFR blockers had higher morbidity of hypertension and neutropenia, but lower risk of side effects of vomiting and anemia. These findings suggest that addition of antiangiogenesis reagents, especially anti-VEGFR-mAb, to the first- or second-line chemotherapy could prolong patient’s OS and PFS time in the advanced or metastatic gastric cancer.…”
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19950por Houtchens, Maria K., Edwards, Natalie C., Schneider, Gary, Stern, Kevin, Phillips, Amy L.“…After matching (n = 2,115 per group), a higher proportion of women with MS than without had claims for premature labor (31.4% vs 27.4%; p = 0.005), infection (13.3% vs 10.9%; p = 0.016), cardiovascular disease (3.0% vs 1.9%; p = 0.028), anemia/acquired coagulation disorders (2.5% vs 1.3%; p = 0.007), neurologic complications (1.6% vs 0.6%; p = 0.005), sexually transmitted diseases (0.4% vs 0.1%; p = 0.045), acquired fetal damage (27.8% vs 23.5%; p = 0.002), and congenital fetal malformations (13.2% vs 10.3%; p = 0.004). …”
Publicado 2018
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19951por Chu, Cindy S, Phyo, Aung Pyae, Lwin, Khin Maung, Win, Htun Htun, San, Thida, Aung, Aye Aye, Raksapraidee, Rattanaporn, Carrara, Verena I, Bancone, Germana, Watson, James, Moore, Kerryn A, Wiladphaingern, Jacher, Proux, Stéphane, Sriprawat, Kanlaya, Winterberg, Markus, Cheah, Phaik Yeong, Chue, Amy L, Tarning, Joel, Imwong, Mallika, Nosten, François, White, Nicholas J“…Recurrence rates and their effects on anemia were compared. RESULTS: Between May 2010 and October 2012, 644 patients were enrolled. …”
Publicado 2018
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19952por He, Ming‐ming, Wang, Feng, Jin, Ying, Yuan, Shu‐qiang, Ren, Chao, Luo, Hui‐yan, Wang, Zhi‐qiang, Qiu, Miao‐zhen, Wang, Zi‐xian, Zeng, Zhao‐lei, Li, Yu‐hong, Wang, Feng‐hua, Zhang, Dong‐sheng, Xu, Rui‐hua“…Grade 3 to 4 toxicities occurred in 22 patients (30.1%) as follows: leukopenia (13.7%), neutropenia (12.3%), anemia (5.5%), thrombocytopenia (1.4%), diarrhea (6.8%), vomiting (2.7%), stomatitis (1.4%), peripheral neuropathy (1.4%), and hand‐foot syndrome (1.4%). …”
Publicado 2018
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19953por Munster, Pamela, Krop, Ian E., LoRusso, Patricia, Ma, Cynthia, Siegel, Barry A., Shields, Anthony F., Molnár, István, Wickham, Thomas J., Reynolds, Joseph, Campbell, Karen, Hendriks, Bart S., Adiwijaya, Bambang S., Geretti, Elena, Moyo, Victor, Miller, Kathy D.“…Grade 3/4 AEs of special interest included neutropenia, fatigue, mucosal inflammation, anemia, thrombocytopenia, febrile neutropenia, and palmar-plantar erythrodysesthesia. …”
Publicado 2018
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19954por Savona, Michael R., Kolibaba, Kathryn, Conkling, Paul, Kingsley, Edwin C., Becerra, Carlos, Morris, John C., Rifkin, Robert M., Laille, Eric, Kellerman, Amy, Ukrainskyj, Stacey M., Dong, Qian, Skikne, Barry S.“…Most common grade 3‐4 TEAEs were neutropenia (n = 13, 42%) and anemia (n = 9, 29%). Ten patients experienced grade 4 neutropenia. …”
Publicado 2018
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19955“…PATIENT CONCERNS AND DIAGNOSIS: A 15-year-old girl presented with a history of bleeding gums and high fever, leukocytosis, anemia, and thrombocytopenia. While waiting the result of bone marrow aspirate, the HLH-associated examinations were abnormal. …”
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19956por Bajpai, Jyoti, Chandrasekharan, Arun, Simha, Vijai, Talreja, Vikas, Karpe, Ashay, Pandey, Nikihil, Singh, Ashish, Rekhi, Bharat, Vora, Tushar, Ghosh, Jaya, Banavali, Shripad, Gupta, Sudeep“…Significant grade 3 or 4 toxicities were febrile neutropenia (51%), thrombocytopenia (36%), and anemia (54%). Histologic response was an independent predictor for EFS and OS in patients who underwent surgery. …”
Publicado 2018
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19957por Park, Sang Hyuk, Jeong, Joseph, Lee, Seon-Ho, Yoo, Dong-Won, Choi, Yunsuk, Jo, Jae-Cheol, Lim, Ji-Hun“…We compared its performance with conventional flow cytometry (C-FCM) for diagnosing overt PNH and detecting minor (0.1–1%) PNH clones in aplastic anemia (AA)/low-grade myelodysplastic syndrome (MDS) patients. …”
Publicado 2019
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19958por Heudobler, Daniel, Klobuch, Sebastian, Thomas, Simone, Hahn, Joachim, Herr, Wolfgang, Reichle, Albrecht“…After cycle 1 of this combined biomodulatory therapy the patient showed hematologic recovery; besides a mild anemia (hemoglobin 11.1 g/dl) she developed a normal blood count. …”
Publicado 2018
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19959por Groenendaal-van de Meent, Dorien, den Adel, Martin, van Dijk, Jan, Barroso-Fernandez, Begona, El Galta, Rachid, Golor, Georg, Schaddelee, Marloes“…BACKGROUND AND OBJECTIVES: Roxadustat is an orally active hypoxia-inducible factor prolyl hydroxylase inhibitor for the treatment of anemia in chronic kidney disease. This study investigated the effect of multiple daily oral doses of omeprazole on the pharmacokinetics, safety, and tolerability of a single oral dose of roxadustat. …”
Publicado 2018
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19960por Özcan, Oğuzhan, Erdal, Hüseyin, İlhan, Gül, Demir, Damla, Gürpınar, Ahmet Burak, Neşelioğlu, Salim, Erel, Özcan“…Of the 54 patients, 46 had homozygous sickle cell anemia (HbSS) and 8 had sickle/β-thalassemia (HbS/β+-thalassemia). …”
Publicado 2018
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