Mostrando 259,201 - 259,220 Resultados de 259,932 Para Buscar '"animal"', tiempo de consulta: 1.22s Limitar resultados
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  14. 259214
    “…A 30-day pre-clinical study in which animals with diabetes were treated with this therapeutic approach provided the proof-of-concept that diabetes CAN BE CURED.Our technology involves a standard-of-care approach already Federal Drug Administration (FDA) approved for cancer treatment (ACT of Chimeric Antigen Receptor, CAR, T cells). …”
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  15. 259215
    “…The Endocrine Society recommends gonadotropin-releasing hormone agonist (GnRHa) therapy for eligible individuals starting at Tanner 2 to halt endogenous pubertal progression, and later testosterone or estradiol treatment. Studies in animals and cisgender adults have shown that sex hormones influence whole-body metabolism and mitochondrial function, but most of the literature has focused on sex differences and the impact of menopause in females. …”
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  16. 259216
    “…Previously, we showed that the in-vitro exposure to EDC inhibited Kiss-induced gene expression in GT1-7 and GN11 cells (donated by Pamela Mellon, UCSD), and altered expression of inflammatory markers in GT1-7 cells and hypothalami of adult male mice.In the present study, we evaluated the effects of the in-vivo exposure to BP2 and BP3 (250 µg/kg/day, orally, for 5 days) on the expression of autophagy markers in hypothalamic nuclei in C57Bl/6 adult male mice, and the in-vitro exposure to BPA, BP2 or BP3 in immortalized GnRH neurons. Animals were sacrificed, brains rapidly dissected and conserved -80°C until processed. …”
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  17. 259217
    “…Pituitary glands were collected from 5 wild type (WT) and 5 prop1 mutant (Mut) animals with 30 (P30), 40, (P40), and 60 (P60) days after birth. …”
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  18. 259218
    “…Both cell lines were injected subcutaneously into the hind flank of Wt SJV129 mice of pediatric age (4-5 weeks) and adult age (20-22 weeks). These animals were monitored for 10 weeks post injection. …”
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  19. 259219
    “…In vitro studies, in vivo studies in animals, and association studies in humans suggest that metformin, an inexpensive medication with a modest side effect profile, may help prevent or treat NMTC. …”
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  20. 259220
    “…Until now most available data are driven from studies on animals, case reports, and a few observed cases on studies.Pathophysiologyis not well understood. …”
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