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259681
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259682por Rubin, Ana, Salzberg, Anna C., Imamura, Yuka, Grivitishvilli, Anzor, Tombran-Tink, Joyce“…Age, weight, and gender-matched mice and wild-type (wt) littermates were treated at 6 weeks (early treatment) or 12 weeks (late treatment) of age for the duration of 6 weeks. Animals were implanted with an osmotic mini pump delivering 0.3 ug/g/day P78-PEDF or vehicle. …”
Publicado 2016
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259683por Chaney, Shawnta Y., Mukherjee, Shradha, Giddabasappa, Anand, Rueda, Elda M., Hamilton, W. Ryan, Johnson, Jerry E., Fox, Donald A.“…To that end, we used our previously published human equivalent murine model of low-level gestational lead exposure (GLE). Children and animals with GLE exhibit increased scotopic electroretinogram a- and b-waves. …”
Publicado 2016
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259684por Jones, Andrew T., Chamcha, Venkateswarlu, Kesavardhana, Sannula, Shen, Xiaoying, Beaumont, David, Das, Raksha, Wyatt, Linda S., LaBranche, Celia C., Stanfield-Oakley, Sherry, Ferrari, Guido, Montefiori, David C., Moss, Bernard, Tomaras, Georgia D., Varadarajan, Raghavan, Amara, Rama Rao“…In this study, we show that a novel trimeric gp120 protein, cycP-gp120, generates high titers of high-avidity and broadly cross-reactive anti-V1V2 antibodies, a result not found in animals immunized with monomeric gp120. These results reveal the potential of cycP-gp120 as a vaccine candidate to induce antibodies associated with reduced risk of HIV-1 infection in humans.…”
Publicado 2018
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259685por Savadelis, Molly D., Roveto, Jennifer L., Ohmes, Cameon M., Hostetler, Joe A., Settje, Terry L., Dzimianski, Michael T., Moorhead, Andrew R.“…Blood samples were collected from all study animals prior to surgical transplantation of adult heartworms, on study days 0, 1, 3, 7, 14, 21, 28, and every 4 weeks thereafter for the duration of this study. …”
Publicado 2018
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259686por Ahmad, Aftab, Al-Abbasi, Fahad A., Sadath, Saida, Ali, Soad Shaker, Abuzinadah, Mohammed F., Alhadrami, Hani A., Mohammad Alghamdi, Anwar Ali, Aseeri, Ali H., Khan, Shah Alam, Husain, Asif“…Group I served as a normal control while Group II served as toxic control for comparison purpose. Experimental animals in Group III, IV, and V were supplemented with fresh CM, (250 mL/24 h/cage), NSO (2 mL/kg/day p. o.), and NSO + fresh CM, respectively. …”
Publicado 2018
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259687por Cotel, Marie-Caroline, Polacek, Romana, Lenartowicz, Ewelina, Natesan, Sridhar, Cooper, Jonathan, Vernon, Anthony“…After 28d treatment, animals were culled and perfused transcardially with 4% PFA. …”
Publicado 2018
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259688por Kanji, Sarah, Gorbovskaya, Ilona, Fonseka, Trehani, Yoshida, Kazunari, Marshe, Victoria, MacKenzie, Malgorzata, Bercik, Premysl, Verdu, Elena, Hahn, Margaret, Mueller, Daniel“…Although several mechanisms have been proposed, the gut microbiome (GMB) has been suggested as a potential mediator of AP-induced metabolic side effects due to its role in weight and metabolic regulation; as well as emerging evidence demonstrating a shift in the microbiome of AP-treated animals and humans. The purpose of the current study is to 1) Investigate the GMB in SCZ patients compared to healthy individuals and 2) To examine the role of GMB in SCZ and AP-induced metabolic side effects. …”
Publicado 2018
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259689por Gregersen, Maja, Clemmensen, Lars, Søndergaard, Anne, Christiani, Camilla Jerlang, Hemager, Nicoline, Ellersgaard, Ditte, Spang, Katrine Søborg, Greve, Aja, Gantriis, Ditte Lou, Knudsen, Christina Bruun, Andreassen, Anna Krogh, Veddum, Lotte, Stadsgaard, Henriette Brockdorff, Bliksted, Vibeke Fuglsang, Mors, Ole, Plessen, Kerstin J, Nordentoft, Merete, Jepsen, Jens Richardt Møllegaard, Thorup, Anne A E“…Social cognitive skills will be assessed with Frith-Happé Animated Triangles and Theory-of-Mind Storybook Frederik. …”
Publicado 2018
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259690por McGreevy, Paul D., Wilson, Bethany J., Mansfield, Caroline S., Brodbelt, Dave C., Church, David B., Dhand, Navneet, Soares Magalhães, Ricardo J., O’Neill, Dan G.“…The median longevity of non-chocolate coloured dogs (n = 139, 12.1 years, IQR 10.2–13.9, range 0.0–16.0) was longer than for chocolate coloured animals (n = 34, 10.7 years, IQR 9.0–12.4, range 3.8–15.5) (P = 0.028). …”
Publicado 2018
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259691por Alharthi, Abdulrahman S., Batistel, Fernanda, Abdelmegeid, Mohamed K., Lascano, Gustavo, Parys, Claudia, Helmbrecht, Ariane, Trevisi, Erminio, Loor, Juan J.Enlace del recurso
Publicado 2018
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259692por da Silva, Helio Rodrigues, Mamani, Javier Bustamante, Nucci, Mariana Penteado, Nucci, Leopoldo Penteado, Kondo, Andrea Tiemi, Fantacini, Daianne Maciely Carvalho, de Souza, Lucas Eduardo Botelho, Picanço-Castro, Virginia, Covas, Dimas Tadeu, Kutner, José Mauro, de Oliveira, Fernando Anselmo, Hamerschlak, Nelson, Gamarra, Lionel Fernel“…Evaluation of the BLI, NIRF, and MRI signals in vivo and ex vivo after labeled hBM-MSC(Luc) were implanted into animals showed differences between different MNP concentrations and signals associated with different techniques (MRI and NIRF; 5 and 20 µg Fe/mL; P < 0.05) in the sham groups at 4 h as well as a time effect (4 h and 6 d; P < 0.001) and differences between the sham and stroke groups in all images signals (P < 0.001). …”
Publicado 2019
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259693por Russell, Ginny, Kapp, Steven K., Elliott, Daisy, Elphick, Chris, Gwernan-Jones, Ruth, Owens, Christabel“…Participants also described specific qualities relating to social interaction, such as honesty, loyalty, and empathy for animals or for other autistic people. In thematic analysis we found that traits associated with autism could be experienced either as advantageous or disadvantageous dependent on moderating influences. …”
Publicado 2019
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259694por Bueno, Ana, More, Candy, Ramalho, Fernando, Moreira, Ayrton, De Castro, Margaret, Rauber Antonini, Sonir“…Once the TuV reached 100 mm(3), we randomized the animals for EB1089 (n=5; 0.8mcg/kg BW) or vehicle [Control group (CG) n=5; 80% propylene glycol-20% PBS] treatment (sc injection; 5 days/week during 5 weeks). …”
Publicado 2019
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259695“…HCPs experienced the OneTouch Verio Reflect glucose meter and the OneTouch Reveal mobile app online from their own office computers using interactive demonstrations via webpages and multiple animations. After providing demographic and clinical practice insights, HCPs responded to statements about the utility of the system. …”
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259696por Raman, Arjun S., Gehrig, Jeanette L., Venkatesh, Siddarth, Chang, Hao-Wei, Hibberd, Matthew C., Subramanian, Sathish, Kang, Gagandeep, Bessong, Pascal O., Lima, Aldo A.M., Kosek, Margaret N., Petri, William A., Rodionov, Dmitry A., Arzamasov, Aleksandr A., Leyn, Semen A., Osterman, Andrei L., Huq, Sayeeda, Mostafa, Ishita, Islam, Munirul, Mahfuz, Mustafa, Haque, Rashidul, Ahmed, Tahmeed, Barratt, Michael J., Gordon, Jeffrey I.“…A consortium of cultured ecogroup taxa, introduced into gnotobiotic piglets, reenacted changes in their relative abundances that were observed in human communities as the animals transitioned from exclusive milk feeding to a fully weaned state consuming a prototypic Bangladeshi diet. …”
Publicado 2019
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259697por Kirkpatrick, Greg, Jones, Courtney, Fosmire, Susan, Porter, Christopher, DiPaola, Jorge“…In continuing our studies, we have generated a transgenic mouse endogenously expressing the ETV6 P214L mutation by CRISPR/Cas9 editing, and these mice appear to have a thrombocytopenic phenotype similar to that observed in patients carrying the ETV6 P214L mutation. These animals will be the focus of our continued investigation of the mechanism by which ETV6 germline mutation results in a predisposition to leukemia. …”
Publicado 2018
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259698por McBride, Matthew, Amezcua, Rocio, Cassar, Glen, O’Sullivan, Terri, Friendship, RobertEnlace del recurso
Publicado 2019
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259699por Manful, Charles F., Vidal, Natalia P., Pham, Thu H., Nadeem, Muhammad, Wheeler, Evan, Hamilton, Melissa C., Doody, Karen M., Thomas, Raymond H.“…Cervids such as moose (Alces alces) are popular as superior sources of low-fat lean meat with balanced omega 6:3 essential fatty acids compared to traditional farm raised or domesticated meat animals due to the forage they consume as a normal part of their diet [2,4,5]. …”
Publicado 2019
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259700por Di Grigoli, Antonino, Bonanno, Adriana, Rabie Ashkezary, Mansour, Laddomada, Barbara, Alabiso, Marco, Vitale, Francesca, Mazza, Francesca, Maniaci, Giuseppe, Ruisi, Paolo, Di Miceli, GiuseppeEnlace del recurso
Publicado 2019
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