“…There is no evidence that removal of the animals from their native environment to the laboratory either increases or decreases the rate of metamorphosis. …”
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“…The result of this study proves that some species of amœbæ from liver abscesses and the human intestine can be cultivated upon various autolyzed tissues of man and some of the lower animals without a symbiotic microorganism. Their cultivation from liver abscesses upon such bacteria-free autolyzed tissue indicates that their multiplication in these lesions depends upon some product or products in the process of dissociation of the liver cells. …”
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“…The rates of disappearance were irregular in different animals and bore no direct relation to the initial titers. …”
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“…In comparison, similar material from cases of epidemic influenza do, however, cause particular changes in the blood and lungs of these animals, cultures of the lungs often yielding Bacterium pneumosintes. …”
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“…They suggest that the prompt rise of antibodies in reinfected animals may play a rôle in the immunity to tuberculosis. …”
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“…To determine, by RT–PCR, the time course of glial fibrillary acidic protein (GFAP), vascular endothelial growth factor (VEGF), and monocyte chemotactic protein-1 (MCP-1) gene expression, we delivered ten laser burns (50 µm, 400 mW, 0.05 s) to each retina in 10–12-week-old mice (group III’, n=10) and 1-year-old mice (group IV’, n=10). Animals from Groups III’ and IV’ had the same age than those from Groups III and IV, but they received ten laser impacts in each eye and served for the molecular analysis. …”
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“…Further, 15 buffaloes, each of control and treatment group, were injected parentrally (deep i/m) with 5 ml of micro-minerals (each ml containing Se, Zn, Cu and Mn at 5, 40, 15 and 10 mg, respectively), twice 2 months before and on the day of calving, keeping rest of the animals (control, n=30 and treatment, n=25) as controls. …”
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“…LDV might be a primary example for the effectiveness of a permanent clonal CTL deletion in adult animals under natural conditions of infection. The presumed modes of transmission of LDV in nature and the events associated with its infection of mice are strikingly similar to those observed during the acute and asymptomatic phases of infection with human immunodeficiency virus (HIV) [24, 29, 74, 78]. …”
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“…A total of 567 cows at the time of calving were enrolled, but for the final analyses only 521 animals were considered. The cows were randomly assigned on a daily basis into 1 of 3 groups: (1) control group (n = 177), (2) application of 20 IU of oxytocin i.m. …”
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“…Part IBiomaterials ScienceBiomaterials Science and EngineeringLearning ObjectivesMaterials Science and EngineeringMultilevels of Structure and Categorization of MaterialsFour Categories of MaterialsDefinitions of Biomaterials, Biomedical Materials, and Biological MaterialsBiocompatibilityChapter HighlightsActivitiesSimple Questions in ClassProblems and ExercisesBibliographyToxicity and CorrosionLearning ObjectivesElements in the BodyBiological Roles and Toxicities of Trace ElementsSelection of Metallic Elements in Medical-Grade AlloysCorrosion of MetalsEnvironment inside the BodyMinimization of Toxicity of Metal ImplantsChapter HighlightsLaboratory Practice 1Simple Questions in ClassProblems and ExercisesAdvanced Topic: Biological Roles of Alloying ElementsBibliographyMechanical Properties of BiomaterialsLearning ObjectivesRole of Implant BiomaterialsMechanical Properties of General ImportanceHardnessElasticity: Resilience and StrechabilityMechanical Properties Terms Used in the Medical CommunityFailureEssential Mechanical Properties of Orthopedic Implant BiomaterialsChapter HighlightsActivitiesSimple Questions in ClassProblems and ExercisesBibliographyMetallic Biomaterials in Orthopedic ImplantsLearning ObjectivesDevelopment of Metallic BiomaterialsStainless SteelsCobalt-Based AlloysTitanium AlloysComparison of Stainless Steels, Cobalt, and Titanium AlloysSummary and RemarksChapter HighlightsActivitiesSimple Questions in ClassProblems and ExercisesBibliographyMetallic Biomaterials: Miscellaneous OthersLearning ObjectivesDental MaterialsNiTi Shape-Memory AlloysOther Clinically Applied Metallic MaterialsNew Metallic Materials: Magnesium AlloysChapter HighlightsLaboratory Practice 2Simple Questions in ClassProblems and ExercisesBibliographyBioinert CeramicsLearning ObjectivesOverview of BioceramicsInert Bioceramics: Al2O3Inert Bioceramics: ZrO2Two Types of JointsSummary and Remarks on Al2O3 and ZrO2Dental CeramicsChapter HighlightsActivitiesSimple Questions in ClassProblems and ExercisesAdvanced Topic: Total Joint ReplacementBibliographyBioactive and Bioresorbable CeramicsLearning ObjectivesOverview of Surface Bioactive and Bulk Degradable CeramicsCalcium Phosphates and HydroxyapatiteBioactive GlassesBioactive Glass-CeramicsBone-Bonding MechanismsBiodegradable CeramicsChapter HighlightsLaboratory Practice 3Simple Questions in ClassProblems and ExercisesAdvanced Topic: Bioceramic Scaffolds for Bone Tissue EngineeringBibliographyPolymeric Biomaterials: FundamentalsLearning ObjectivesBasic Concepts on PolymersOverview of Polymeric BiomaterialsChapter HighlightsActivitiesSimple Questions in ClassProblems and ExercisesAdvanced Topic: Polymers and Polymer Scaffolds for Soft Tissue EngineeringBibliographyBioinert PolymersLearning ObjectivesPolyolefinPoly(Ethylene Terephthalate)Acrylate PolymerFluorocarbon PolymersSiliconePolyurethaneChapter HighlightsActivitiesSimple Questions in ClassProblems and ExercisesAdvanced Topic: Properties and Applications of Polyurethane as BiomaterialsBibliographyBioresorbable PolymersLearning ObjectivesBiodegradation of PolymersPolyesters: PGA, PLA, and PCLPolyesters: PHAElastomeric Polyester: Poly(Polyol Sebacate)Polyether: Poly(Ethylene Glycol)PolyamideSurface-Erodible PolymersBiological PolymersChapter HighlightsSimple Questions in ClassProblems and ExercisesLaboratory Practice 4Advanced Topic: Natural Polymers: Resilin, Silk, and GlutenBibliographyComposite BiomaterialsLearning ObjectivesOverview of CompositesNatural Composites: BoneDental CompositesArtificial BoneChapter HighlightsLaboratory Practice 5Simple Questions in ClassProblems and ExercisesAdvanced Topic: Development of Artificial Bone: Composites and ScaffoldsBibliographyPart IIMedical ScienceMedicine and Medical ScienceLearning ObjectivesMedicine and Medical ScienceMedical Science versus Materials ScienceLearning Goals of Part IIChapter HighlightsActivityBibliographyImage LinksSimple Questions in ClassProblems and ExercisesHuman Anatomy And Diseases I: Integumentary, Skeletal, Muscular, Nervous, and Endocrine SystemsLearning ObjectivesIntegumentary SystemSkeletal SystemMuscular SystemNervous SystemEndocrine SystemChapter HighlightsActivitiesSimple Questions in ClassProblems and ExercisesAdvanced Topic: Biomaterial Challenges in Bone Tissue EngineeringBibliographyHuman Anatomy And Diseases II: Cardiovascular SystemLearning ObjectivesAnatomy and Functions of the Cardiovascular SystemCardiovascular DiseaseCardiac Performance: P-V LoopCurrent Therapies for Heart DiseaseAlternative Treatments and Application of BiomaterialsArtificial Blood VesselsChapter HighlightsActivitiesSimple Questions in ClassProblems and ExercisesBibliographyHuman Anatomy And Diseases III: Respiratory, Lymphatic, Digestive, Urinary, and Reproductive SystemsLearning ObjectivesRespiratory SystemLymphatic SystemDigestive SystemUrinary SystemReproductive SystemChapter HighlightsActivitiesSimple Questions in ClassProblems and ExercisesBibliographyCells and BiomoleculesLearning ObjectivesIntroductionCell Biochemistry and BiosynthesisCell StructureTransport across Plasma MembranesCell ProliferationCell Differentiation and Stem CellsChapter HighlightsActivitiesAdvanced Topic: Cell Therapy to Treat Cardiac DiseaseStrategies to Address Immune Rejection in CellsSummary of Cell-Based Therapies and Their LimitationsSimple Questions in ClassProblems and ExercisesBibliographyHistology and Tissue Properties I: Epithelial, Neuronal, and Muscle TissueLearning ObjectivesIntroductionEpitheliumMuscular TissueNervous TissueChapter HighlightsActivitiesAdvanced Topic: Properties of Proteins in Mammalian TissuesSimple Questions in ClassProblems and ExercisesBibliographyHistology and Tissue Properties II: Connective TissuesLearning ObjectivesOverview of Connective TissuesTypes of Connective TissueConnective Tissue Proper (Skin, Tendon, Ligament)Mechanical Properties of Structural ProteinsCartilageBoneChapter HighlightsLaboratory Practice 6Simple Questions in ClassProblems and ExercisesBibliographyImmune System and Body Responses to BiomaterialsLearning ObjectivesImmune SystemTissue Response to InjuriesBody Response to ImplantsChapter HighlightsActivitiesSimple Questions in ClassProblems and ExercisesBibliographyEvaluation of BiomaterialsLearning ObjectivesOverview of Biomaterials EvaluationStandardsToxicological EvaluationCytotoxicity TestingEvaluation in AnimalsChapter HighlightsLaboratory Practice 7Case Study: Evaluation of Heart Patch in RatsSimple Questions in ClassProblems and ExercisesBibliographyRegulation of Medical DevicesLearning ObjectivesRegulations versus StandardsMedical DevicesPreclinical TestingClinical TrialsDevelopment of Medical Devices and Possible Career OpportunitiesChapter HighlightsActivitiesSimple Questions in ClassProblems and ExercisesBibliographyIndex.…”
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“…He scored only 55 out of 100 on the Addenbrooke’s Cognitive Examination-III, with impairments across domains but with particularly poor executive function (naming only two words beginning with P in a minute, and only 10 animals over a minute, leading to a very low verbal fluency score of 4 out of 14). …”
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“…This model is reproducible, cost effective, permits analyses of the early events that lead to joint fibrosis and stiffness, can be readily employed with transgenic animals, and will allow evaluation of therapeutic interventions. …”
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“…Co-designed with parents and based on decades of parenting research, Parent Positive consists of three elements: (i) Parenting Boosters: where advice, delivered in the form of narrated animations, videos, graphics and text is provided to help parents with eight common parenting challenges; (ii) Parenting Exchange: a facilitated parent-to-parent communication and peer support platform and; (iii) Parent Resources: giving access to carefully selected high-quality, evidence-based online parenting resources. …”
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