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“…In the context of the contact farm animals had with human, the impact of genetic forces including admixture, mutation, recombination rate, selection, and effective population size on LD is discussed. …”
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“…For this reason, a well-established preclinical model of pancreatic cancer must be established to allow further exploration of the occurrence, development, invasion, and metastasis mechanism of pancreatic cancer, as well as to facilitate research into new therapeutic targets. A large number of animal models of pancreatic cancer are currently available, including a cancer cell line-based xenograft, a patient-derived xenograft, several mouse models (including transgenic mice), and organoid models. …”
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“…It is essential to understand the advantages and disadvantages of each animal model in terms of the accuracy and effectiveness of the experiment. …”
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“…By means of a mathematical model, it was concluded that when vaccination is applied on 95% of animals even for 3 years, bluetongue cannot be eradicated and is able to re‐emerge. …”
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“…Food and feed samples used to estimate human and animal dietary exposure were analysed for the 12 main C. purpurea EAs: ergometrine, ergosine, ergocornine, ergotamine, ergocristine, ergocryptine (α‐ and β‐isomers) and their corresponding –inine (S)‐epimers. …”
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“…Animal movement comes in a variety of ‘types’ including small foraging movements, larger one-way dispersive movements, seasonally-predictable round-trip migratory movements, and erratic nomadic movements. …”
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“…Although to date there is no animal model for INOCA, animal models of CMD, one of the hallmarks of INOCA, offer excellent test models for enhancing our understanding of the pathophysiology of CMD and for investigating novel therapies. …”
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“…Thus, we concluded that PAHs have a toxicity for aquatic animals, indicating that we should emphasize the prevention of aquatic PAH pollution.…”
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“…Aside to the infection in animals, zoonotic significance of the animal rotaviruses has to be further unearthed. …”
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“…By observing that the frontal facial image of both humans and animals, is the one having the minimum rank of all different poses, a model which is able to jointly recover the frontalized version of the face as well as the facial landmarks is devised. …”
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“…Providing protective immunity to neonatal animals in early life is associated with numerous challenges regarding vaccine safety and efficacy. …”
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“…For scientific and regulatory requirements, such new vaccines must first be evaluated at the preclinical level, and there is a continuing quest for the ideal animal model with which to perform such studies. The main advantages and limitations of murine models, those most commonly used for human vaccine research, and of large animal models are reviewed and discussed.…”
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“…The ingestion of plastics appears to be widespread throughout the animal kingdom with risks to individuals, ecosystems and human health. …”
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“…The use of high bio-containment facilities, such as the CSIRO Australian Animal Health Laboratory, plays a key role studying these dangerous pathogens and facilitates the development of countermeasures. …”
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“…It is being increasingly accepted that bats are potential reservoirs of a large number of known and unknown viruses, many of which could spillover into animal and human populations. However, our knowledge into basic bat biology and immunology is very limited and we have little understanding of major factors contributing to the risk of bat virus spillover events. …”
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