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5401“…Despite significant progress in recent clinical trials for hemophilia, new immunotoxicities to AAV and transgene are emerging in humans that require better animal models to assess and overcome these responses. …”
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5402por Kieslinger, Matthias, Swoboda, Alexander, Kramer, Nina, Pratscher, Barbara, Wolfesberger, Birgitt, Burgener, Iwan A.“…The incidence by which different types of cancers occur in companion animals as well as mechanisms of disease are unique between humans and companion animals, where one can learn from each other. …”
Publicado 2019
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5404por Rioja-Lang, Fiona C., Connor, Melanie, Bacon, Heather J., Lawrence, Alistair B., Dwyer, Cathy M.“…Prioritization of animal welfare issues can help identify which areas most require research funding and raise awareness of best practices. …”
Publicado 2020
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5405
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5406
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5407
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5408por FUNATO, Hiromasa“…Forward genetics is a powerful approach to understand the molecular basis of animal behaviors. Fruit flies were the first animal to which this genetic approach was applied systematically and have provided major discoveries on behaviors including sexual, learning, circadian, and sleep-like behaviors. …”
Publicado 2020
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5409por Alkaff, Syed Abdullah, Radhakrishnan, Krishna, Nedumaran, Anu Maashaa, Liao, Ping, Czarny, Bertrand“…This review supports the existing literature by systematizing presently available data and accounting for the differences in drugs of choice, carrier types, animal models, intervention strategies and outcome parameters.…”
Publicado 2020
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5410por Jalgaonkar, Sharmila V., Joshi, Shirish S., Gajbhiye, Snehalata V., Singh, Kritarth Naman M., Sayyed, Mohsin P.“…MATERIALS AND METHODS: A questionnaire-based survey was conducted in 30 postgraduate pharmacology students who had used the animal simulation software and had completed at least five isolated tissue experiments. …”
Publicado 2019
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5411por Montenegro, Omar, Illescas, Soledad, González, José Carlos, Padilla, David, Villarejo, Pedro, Baladrón, Victor, Galán, Rocio, Bejarano, Natalia, Medina-Prado, Lucia, Villaseca, Natalia, Pérez-Ortiz, José Manuel, Muñoz-Rodríguez, José Ramón, Santiago, Juan Luis, Redondo, Francisco Javier“…OBJECTIVE: The aim of the study was to develop a model of abdominal sepsis in the experimental animal. MATERIAL AND METHODS: Sprague-Dawley male rats of 5 weeks (N=39) were used. …”
Publicado 2020
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5412“…Alongside clinical achievements, experiments conducted on animal models (including primate or non-primate) have been effective in the understanding of various pathophysiological aspects of perinatal hypoxic/ischemic encephalopathy (HIE). …”
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5413“…CONCLUSIONS: This database, the first of its kind in livestock animals, will provide a useful exploratory tool to assist functional annotation of animal genomes.…”
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5414por Pent, Gabriel J, Greiner, Scott P, Munsell, John F, Tracy, Benjamin F, Fike, John H“…Lambs in silvopastures spent more time lying down than animals in the open pastures (P ≤ 0.01), while lambs in the open pastures spent more than 2 h longer each day standing (P < 0.0001). …”
Publicado 2019
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5415por Pourghadamyari, Hossein, Rezaei, Mohammad, Ipakchi-Azimi, Ali, Eisa-Beygi, Shahram, Basiri, Mohsen, Tahamtani, Yaser, Baharvand, Hossein“…Therefore, the zebrafish can be considered as an ideal animal model in muscle regeneration studies. In this study, Tol2 transposase was applied to produce Tg(mylpfa: cfp-nfsB) zebrafish model that express a fusion protein composed of cyan fluorescent protein (CFP) and nitrorudactase (NTR) under control of mylpfa promoter. …”
Publicado 2019
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5416por Bampidis, Vasileios, Azimonti, Giovanna, Bastos, Maria de Lourdes, Christensen, Henrik, Dusemund, Birgit, Kouba, Maryline, Kos Durjava, Mojca, López‐Alonso, Marta, López Puente, Secundino, Marcon, Francesca, Mayo, Baltasar, Pechová, Alena, Petkova, Mariana, Ramos, Fernando, Sanz, Yolanda, Villa, Roberto Edoardo, Woutersen, Ruud, Aquilina, Gabriele, Bories, Georges, Gropp, Jürgen, Nebbia, Carlo, Innocenti, Matteo Lorenzo“…Following a request from the European Commission, the Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) was asked to deliver a scientific opinion on the safety of butylated hydroxy anisole (BHA) for all animal species. …”
Publicado 2019
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5417por Ardizzone, Michele, Binaglia, Marco, Cottrill, Bruce, Cugier, Jean‐Pierre, Ferreira, Lucien, Gómez Ruiz, Jose Ángel, Innocenti, Matteo, Ioannidou, Sofia, López Puente, Secundino, Merten, Caroline, Nikolic, Marina, Savoini, Giovanni“…At EFSA, animal dietary exposure estimates are undertaken by several Panels/Units to assess the risk of feed contaminants, pesticide residues, genetically modified feed and feed additives. …”
Publicado 2019
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5418Publicado 2018“…EFSA was requested by the European Commission to consider the impact of glyphosate residues in feed on animal health in accordance with Article 31 of Regulation (EC) No 178/2002. …”
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5419“…Food and feed samples used to estimate human dietary and animal exposure were reported either as the individual results for T2 and/or, HT2, and/or as the sum of the two. …”
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5420por Folly, Arran J., Dorey-Robinson, Daniel, Hernández-Triana, Luis M., Phipps, L. Paul, Johnson, Nicholas“…Worldwide, arthropod-borne disease transmission represents one of the greatest threats to public and animal health. For the British Isles, an island group on the north-western coast of continental Europe consisting of the United Kingdom (UK) and the Republic of Ireland, physical separation offers a barrier to the introduction of many of the pathogens that affect animals on the rest of the continent. …”
Publicado 2020
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