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Mostrando 221 - 240 Resultados de 120,423 Para Buscar '"apoptosis"', tiempo de consulta: 0.38s Limitar resultados
  1. 221
    “…Survival and apoptosis are of major importance in the osteoclast life cycle. …”
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    Positive and negative regulators of osteoclast apoptosis
  2. 222
    “…For the last two decades, caspases, a family of cysteine-aspartic proteases, have evolved from being considered solely as regulators of apoptosis or inflammation to having a wider range of functions. …”
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    Brainiac Caspases: Beyond the Wall of Apoptosis
  3. 223
    “…This review dissects the apoptosis pathways implicated in pediatric tumors. …”
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    Destined to Die: Apoptosis and Pediatric Cancers
  4. 224
    “…Thus, there is a need to focus on identifying potential drugs that restore apoptosis in cancer cells. Here, we discuss the major inducers of apoptosis mediated through various mechanisms and their usefulness as potential future treatment options for ovarian cancer. …”
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    Therapeutic Inducers of Apoptosis in Ovarian Cancer
  5. 225
    por Zi, Mengting, Xu, Yuekang
    Publicado 2018
    “…Here, we summarize the latest development of studies on the pathophysiological functions of cystatin C, with focus on its immune regulatory roles at both cellular and molecular levels including antigen presentation, secretion of cytokines, synthesis of nitric oxide, as well as apoptosis. Finally, we discuss the clinical implications and therapeutic potentials of what this predominantly expressed protease inhibitor can bring to us.…”
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    Involvement of cystatin C in immunity and apoptosis
  6. 226
    “…Recent neuropathological studies of experimental autoimmune encephalomyelitis have focused attention on the high number of cells in the lesions that show typical morphological features of apoptosis. Surprisingly, it has turned out that the vast majority of apoptotic cells are T lymphocytes and that they actually represent the antigen-specific T-cell population responsible for the induction of the disease. …”
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    Apoptosis in brain-specific autoimmune disease
  7. 227
    por Saikumar, Pothana, Kar, Rekha
    Publicado 2010
    “…In multicellular organisms, cell death plays an important role in development, morphogenesis, control of cell numbers, and removal of infected, mutated, or damaged cells. The term apoptosis was first coined in 1972 by Kerr et al.1 to describe the morphologic features of a type of cell death that is distinct from necrosis and is today considered to represent programmed cell death. …”
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    Apoptosis and Cell Death: Relevance to Lung
  8. 228
    por Bucur, Octavian
    Publicado 2016
    “…This brief review summarizes our current knowledge on the microRNAs that regulate apoptosis machinery and are potentially involved in the dysregulation or deregulation of apoptosis, a well known hallmark of cancer. microRNAs are critical regulators of the most important cellular processes, including apoptosis. …”
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    microRNA regulators of apoptosis in cancer
  9. 229
    por Yue, Jicheng, López, José M.
    Publicado 2020
    “…As we will see, apoptosis is plagued with multiple positive feedback loops. …”
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    Understanding MAPK Signaling Pathways in Apoptosis
  10. 230
    por Wang, Hsiuying
    Publicado 2020
    “…The microRNAs (miRNAs) play important roles in CRC treatment resistance and CRC progression and apoptosis. This review discusses the role of miRNAs in contributing to the promotion or inhibition of apoptosis in CRC and the role of miRNAs in modulating treatment resistance in CRC cells.…”
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    MicroRNAs and Apoptosis in Colorectal Cancer
  11. 231
    “…Early studies of the free-living nematode C. elegans informed us how BCL-2-regulated apoptosis in humans is regulated. However, subsequent studies showed C. elegans apoptosis has several unique features compared with human apoptosis. …”
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    Diversity in the intrinsic apoptosis pathway of nematodes
  12. 232
    “…Apoptosis plays a major role in development, tissue renewal and the progression of degenerative diseases. …”
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    Acetylcholinesterase promotes apoptosis in insect neurons
  13. 233
    por Perez-Fidalgo, J. Alejandro
    Publicado 2020
    “…In this review, the most relevant evidence of clinical studies in ovarian cancer with compounds targeting cell cycle or promoting apoptosis is summarised.…”
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    Cell proliferation inhibitors and apoptosis promoters
  14. 234
    por Ko, Il-Gyu
    Publicado 2020
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    Therapeutic Strategies Against Apoptosis and Gliosis
  15. 235
    “…Processes such as programmed cell death or apoptosis has long been known to occur during development to help sculpt organs and tissue systems. …”
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    Senescence and Apoptosis: Architects of Mammalian Development
  16. 236
    por Qin, Yiren, Wen, Duancheng
    Publicado 2021
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    Breakthrough of interspecific chimerism: blocking apoptosis
  17. 237
    “…Ca(2+) has been shown to regulate opposing functions such as autophagy, that promote cell survival; on the other hand, Ca(2+) also regulates programmed cell death processes such as apoptosis. The functional significance of the TRP/Orai channels has been elaborately studied; however, information on how they can modulate opposing functions and modulate function in excitable and non-excitable cells is limited. …”
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    Calcium Signaling Regulates Autophagy and Apoptosis
  18. 238
    por Knabe, Wolfgang, Washausen, Stefan
    Publicado 2022
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    Editorial: Apoptosis and Senescence in Vertebrate Development
  19. 239
    “…Apoptosis was a natural, non-inflammatory, energy-dependent form of programmed cell death (PCD) that can be discovered in a variety of physiological and pathological processes. …”
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    Radionuclide imaging of apoptosis for clinical application
  20. 240
    “…Here, we report the development of optogenetically controlled cell death effectors (optoCDEs), a novel class of optogenetic tools that enables light-mediated induction of three types of programmed cell death (PCD)—apoptosis, pyroptosis, and necroptosis—using Arabidopsis thaliana photosensitive protein Cryptochrome-2. …”
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    Optogenetic activators of apoptosis, necroptosis, and pyroptosis
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