Mostrando 41 - 60 Resultados de 120,423 Para Buscar '"apoptosis"', tiempo de consulta: 0.42s Limitar resultados
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    “…It has several binding partners and has been implicated in various functions ranging from stress response, control of cell proliferation, and inhibition/prevention of apoptosis. The activity of this protein involves different structural and functional mechanisms, and minor alterations in its expression level may lead to serious biological consequences, including neurodegeneration. …”
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    por Stoian, M, State, N, Stoica, V, Radulian, G
    Publicado 2014
    “…Abstract Apoptosis is an inborn process that has been preserved during evolution; it allows the cells to systematically inactivate, destroy and dispose of their own components thus leading to their death. …”
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  5. 45
    “…For identification of apoptosis, immunohistochemistry with terminal deoxynucleotidyl transferase (TdT)-mediated dUTP-biotin nick end-labeling was performed, in addition, apoptosis was confirmed morphologically by confocal laser scanning microscopy with propidium iodide. …”
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  6. 46
    “…Hepatocyte apoptosis plays important roles in both the removal of external microorganisms and the occurrence and development of liver diseases. …”
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  7. 47
    “…Aging is associated with high morbidity and a poor prognosis in patients with various liver diseases, including nonalcoholic fatty liver disease, hepatitis C and liver cancer, as well as with surgeries such as partial hepatectomy and liver transplantation. In addition, apoptosis increases with liver aging. Because apoptosis is involved in regeneration, fibrosis and cancer prevention during liver aging, and restoration of the appropriate level of apoptosis can alleviate the adverse effects of liver aging, it is important to understand the mechanisms underlying this process. …”
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    “…Targeting delayed/inhibited apoptosis is a major approach in cancer treatment and a highly active area of research. …”
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  11. 51
    por Voss, Anne K., Strasser, Andreas
    Publicado 2020
    “…In recent years, the essentials of developmental apoptosis have emerged. We hypothesize that apoptosis is predominantly required to balance cell proliferation. …”
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  12. 52
    “…To resist viral infection, host organisms clear infected cells and viruses via apoptosis. However, throughout their long-term competition with host cells, enteroviruses have evolved a series of mechanisms to regulate the balance of apoptosis in order to replicate and proliferate. …”
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    “…Therefore, it is very important to study the apoptosis of eosinophils and their survival factors to understand how to develop new drugs based on the modulation of eosinophil apoptosis for the treatment of asthma and allergic diseases. …”
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  14. 54
    “…Apoptosis and clearance of dead cells is highly evolutionarily conserved from nematode to humans, which is crucial to the growth and development of multicellular organism. …”
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    “…Paradoxically, high-grade cancers are generally associated with high constitutive levels of apoptosis. In cancer, cell-autonomous apoptosis constitutes a common tumour suppressor mechanism, a property which is exploited in cancer therapy. …”
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  16. 56
    por Sorice, Maurizio
    Publicado 2022
    “…Autophagy and apoptosis represent two fundamental pathophysiological mechanisms of cell fate regulation. …”
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